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鳥越 俊彦 トリゴエ トシヒコ

所属部署名病理学第一講座
職名教授ホームページURLhttp://web.sapmed.ac.jp/patho1/research/report02.html
更新日 :2017/09/13

プロフィール

研究キーワード

    腫瘍免疫学 細胞生物学 病理学

研究分野

  • 腫瘍学 / 腫瘍生物学 / がん免疫療法

学位

  • 博士(医学)(札幌医科大学)

学歴

  • -
    1984年
    防衛省 防衛医科大学校(日本)

所属学協会

  • 日本癌学会
  • 日本病理学会評議員
  • 日本免疫学会評議員
  • 米国癌学会
  • 国際細胞ストレス学会
  • 日本内科学会
  • 日本宇宙生物学会
所属学協会を全て表示する
所属学協会閉じる
  • 日本癌学会
  • 日本病理学会評議員
  • 日本免疫学会評議員
  • 米国癌学会
  • 国際細胞ストレス学会
  • 日本内科学会
  • 日本宇宙生物学会

研究活動

論文

  • Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts.
    Ota D, Kanayama M, Matsui Y, Ito K, Maeda N, Kutomi G, Hirata K, Torigoe T, Sato N, Takaoka A, Chambers AF, Morimoto J, Uede T
    Journal of molecular medicine (Berlin, Germany) 2014年08月 [査読有り]
  • Specific targeting of a naturally presented osteosarcoma antigen, papillomavirus binding factor peptide, using an artificial monoclonal antibody.
    Tsukahara T, Emori M, Murata K, Hirano T, Muroi N, Kyono M, Toji S, Watanabe K, Torigoe T, Kochin V, Asanuma H, Matsumiya H, Yamashita K, Himi T, Ichimiya S, Wada T, Yamashita T, Hasegawa T, Sato N
    The Journal of biological chemistry 289 22035-22047 2014年08月 [査読有り]
  • PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.
    Kasamatsu J, Takahashi S, Azuma M, Matsumoto M, Morii-Sakai A, Imamura M, Teshima T, Takahashi A, Hirohashi Y, Torigoe T, Sato N, Seya T
    Immunobiology 2014年08月 [査読有り]
  • Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.
    Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N
    Cancer science 105 389-395 2014年04月 [査読有り]
  • Hypoxia-inducible factor (HIF)-independent expression mechanism and novel function of HIF prolyl hydroxylase-3 in renal cell carcinoma.
    Tanaka T, Torigoe T, Hirohashi Y, Sato E, Honma I, Kitamura H, Masumori N, Tsukamoto T, Sato N
    Journal of cancer research and clinical oncology 140 503-513 2014年03月 [査読有り]
  • Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
    Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
    The Journal of pathology 232 199-209 2014年01月 [査読有り]
  • Production of multiple CTL epitopes from multiple tumor-associated antigens.
    Morita R, Hirohashi Y, Nakatsugawa M, Kanaseki T, Torigoe T, Sato N
    Methods in molecular biology (Clifton, N.J.) 1139 345-355 2014年 [査読有り]
  • [The path to innovative drug development of cancer vaccine: from discovery of tumor antigens to clinical trials].
    Torigoe T, Hirohashi Y, Tsukahara T, Kanaseki T, Kochin V, Sato N
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 37 90-95 2014年 [査読有り]
  • Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication.
    Yamamoto T, Tamura Y, Kobayashi J, Kamiguchi K, Hirohashi Y, Miyazaki A, Torigoe T, Asanuma H, Hiratsuka H, Sato N
    Experimental cell research 319 2617-2626 2013年10月 [査読有り]
  • Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.
    Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N
    Biochemical and biophysical research communications 439 96-102 2013年09月 [査読有り]
論文を全て表示する
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  • Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts.
    Ota D, Kanayama M, Matsui Y, Ito K, Maeda N, Kutomi G, Hirata K, Torigoe T, Sato N, Takaoka A, Chambers AF, Morimoto J, Uede T
    Journal of molecular medicine (Berlin, Germany) 2014年08月 [査読有り]
  • Specific targeting of a naturally presented osteosarcoma antigen, papillomavirus binding factor peptide, using an artificial monoclonal antibody.
    Tsukahara T, Emori M, Murata K, Hirano T, Muroi N, Kyono M, Toji S, Watanabe K, Torigoe T, Kochin V, Asanuma H, Matsumiya H, Yamashita K, Himi T, Ichimiya S, Wada T, Yamashita T, Hasegawa T, Sato N
    The Journal of biological chemistry 289 22035-22047 2014年08月 [査読有り]
  • PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.
    Kasamatsu J, Takahashi S, Azuma M, Matsumoto M, Morii-Sakai A, Imamura M, Teshima T, Takahashi A, Hirohashi Y, Torigoe T, Sato N, Seya T
    Immunobiology 2014年08月 [査読有り]
  • Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.
    Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N
    Cancer science 105 389-395 2014年04月 [査読有り]
  • Hypoxia-inducible factor (HIF)-independent expression mechanism and novel function of HIF prolyl hydroxylase-3 in renal cell carcinoma.
    Tanaka T, Torigoe T, Hirohashi Y, Sato E, Honma I, Kitamura H, Masumori N, Tsukamoto T, Sato N
    Journal of cancer research and clinical oncology 140 503-513 2014年03月 [査読有り]
  • Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
    Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
    The Journal of pathology 232 199-209 2014年01月 [査読有り]
  • Production of multiple CTL epitopes from multiple tumor-associated antigens.
    Morita R, Hirohashi Y, Nakatsugawa M, Kanaseki T, Torigoe T, Sato N
    Methods in molecular biology (Clifton, N.J.) 1139 345-355 2014年 [査読有り]
  • [The path to innovative drug development of cancer vaccine: from discovery of tumor antigens to clinical trials].
    Torigoe T, Hirohashi Y, Tsukahara T, Kanaseki T, Kochin V, Sato N
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 37 90-95 2014年 [査読有り]
  • Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication.
    Yamamoto T, Tamura Y, Kobayashi J, Kamiguchi K, Hirohashi Y, Miyazaki A, Torigoe T, Asanuma H, Hiratsuka H, Sato N
    Experimental cell research 319 2617-2626 2013年10月 [査読有り]
  • Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.
    Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N
    Biochemical and biophysical research communications 439 96-102 2013年09月 [査読有り]
  • Human endoplasmic reticulum oxidoreductin 1-α is a novel predictor for poor prognosis of breast cancer.
    Kutomi G, Tamura Y, Tanaka T, Kajiwara T, Kukita K, Ohmura T, Shima H, Takamaru T, Satomi F, Suzuki Y, Torigoe T, Sato N, Hirata K
    Cancer science 104 1091-1096 2013年08月 [査読有り]
  • Constitutive expression and activation of stress response genes in cancer stem-like cells/tumour initiating cells: potent targets for cancer stem cell therapy.
    Torigoe T, Hirohashi Y, Yasuda K, Sato N
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 29 436-441 2013年08月 [査読有り]
  • Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells.
    Matsuzaki J, Torigoe T, Hirohashi Y, Tamura Y, Asanuma H, Nakazawa E, Saka E, Yasuda K, Takahashi S, Sato N
    Pathology international 63 391-397 2013年08月 [査読有り]
  • Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts.
    Ikeda K, Torigoe T, Matsumoto Y, Fujita T, Sato N, Yotsuyanagi T
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 21 616-623 2013年07月 [査読有り]
  • Cytotoxic T lymphocytes: the future of cancer stem cell eradication?
    Saijo H, Hirohashi Y, Torigoe T, Kochin V, Takahashi H, Sato N
    Immunotherapy 5 549-551 2013年06月 [査読有り]
  • DNA methyltransferase 1 is essential for initiation of the colon cancers.
    Morita R, Hirohashi Y, Suzuki H, Takahashi A, Tamura Y, Kanaseki T, Asanuma H, Inoda S, Kondo T, Hashino S, Hasegawa T, Tokino T, Toyota M, Asaka M, Torigoe T, Sato N
    Experimental and molecular pathology 94 322-329 2013年04月 [査読有り]
  • Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor.
    Nishida S, Hirohashi Y, Torigoe T, Inoue R, Kitamura H, Tanaka T, Takahashi A, Asanuma H, Masumori N, Tsukamoto T, Sato N
    Cancer science 104 431-436 2013年04月 [査読有り]
  • Prognostic impact of the expression of ALDH1 and SOX2 in urothelial cancer of the upper urinary tract.
    Kitamura H, Torigoe T, Hirohashi Y, Asanuma H, Inoue R, Nishida S, Tanaka T, Fukuta F, Masumori N, Sato N, Tsukamoto T
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 26 117-124 2013年01月 [査読有り]
  • Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients.
    Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K
    Cancer science 104 124-129 2013年01月 [査読有り]
  • Nuclear, but not cytoplasmic, localization of survivin as a negative prognostic factor for survival in upper urinary tract urothelial carcinoma.
    Kitamura H, Torigoe T, Hirohashi Y, Asanuma H, Inoue R, Nishida S, Tanaka T, Masumori N, Sato N, Tsukamoto T
    Virchows Archiv : an international journal of pathology 462 101-107 2013年01月 [査読有り]
  • Expression and function of FERMT genes in colon carcinoma cells.
    Kiriyama K, Hirohashi Y, Torigoe T, Kubo T, Tamura Y, Kanaseki T, Takahashi A, Nakazawa E, Saka E, Ragnarsson C, Nakatsugawa M, Inoda S, Asanuma H, Takasu H, Hasegawa T, Yasoshima T, Hirata K, Sato N
    Anticancer research 33 167-173 2013年01月 [査読有り]
  • ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis.
    Kuroda T, Hirohashi Y, Torigoe T, Yasuda K, Takahashi A, Asanuma H, Morita R, Mariya T, Asano T, Mizuuchi M, Saito T, Sato N
    PloS one 8 e65158 2013年 [査読有り]
  • Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.
    Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, Kochin V, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N
    PloS one 8 e68187 2013年 [査読有り]
  • Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.
    Takahashi A, Hirohashi Y, Torigoe T, Tamura Y, Tsukahara T, Kanaseki T, Kochin V, Saijo H, Kubo T, Nakatsugawa M, Asanuma H, Hasegawa T, Kondo T, Sato N
    PloS one 8 e69095 2013年 [査読有り]
  • Potential survival benefit of anti-apoptosis protein: survivin-derived peptide vaccine with and without interferon alpha therapy for patients with advanced or recurrent urothelial cancer--results from phase I clinical trials.
    Tanaka T, Kitamura H, Inoue R, Nishida S, Takahashi-Takaya A, Kawami S, Torigoe T, Hirohashi Y, Tsukamoto T, Sato N, Masumori N
    Clinical & developmental immunology 2013 262967 2013年 [査読有り]
  • High expression of CD109 antigen regulates the phenotype of cancer stem-like cells/cancer-initiating cells in the novel epithelioid sarcoma cell line ESX and is related to poor prognosis of soft tissue sarcoma.
    Emori M, Tsukahara T, Murase M, Kano M, Murata K, Takahashi A, Kubo T, Asanuma H, Yasuda K, Kochin V, Kaya M, Nagoya S, Nishio J, Iwasaki H, Sonoda T, Hasegawa T, Torigoe T, Wada T, Yamashita T, Sato N
    PloS one 8 e84187 2013年 [査読有り]
  • Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes.
    Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
    Cell stress & chaperones 17 757-763 2012年11月 [査読有り]
  • High expression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cell carcinomas correlates to lymph node metastasis.
    Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Kobayashi J, Sasaki T, Fujino J, Asanuma H, Tamura Y, Nakamori K, Hasegawa T, Hiratsuka H, Sato N
    Pathology international 62 684-689 2012年10月 [査読有り]
  • Cancer classification using the Immunoscore: a worldwide task force.
    Galon J, Pagès F, Marincola FM, Angell HK, Thurin M, Lugli A, Zlobec I, Berger A, Bifulco C, Botti G, Tatangelo F, Britten CM, Kreiter S, Chouchane L, Delrio P, Arndt H, Asslaber M, Maio M, Masucci GV, Mihm M, Vidal-Vanaclocha F, Allison JP, Gnjatic S, Hakansson L, Huber C, Singh-Jasuja H, Ottensmeier C, Zwierzina H, Laghi L, Grizzi F, Ohashi PS, Shaw PA, Clarke BA, Wouters BG, Kawakami Y, Hazama S, Okuno K, Wang E, O'Donnell-Tormey J, Lagorce C, Pawelec G, Nishimura MI, Hawkins R, Lapointe R, Lundqvist A, Khleif SN, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Palmqvist R, Nagtegaal ID, Wang Y, D'Arrigo C, Kopetz S, Sinicrope FA, Trinchieri G, Gajewski TF, Ascierto PA, Fox BA
    Journal of translational medicine 10 205 2012年10月 [査読有り]
  • SYT-SSX breakpoint peptide vaccines in patients with synovial sarcoma: a study from the Japanese Musculoskeletal Oncology Group.
    Kawaguchi S, Tsukahara T, Ida K, Kimura S, Murase M, Kano M, Emori M, Nagoya S, Kaya M, Torigoe T, Ueda E, Takahashi A, Ishii T, Tatezaki S, Toguchida J, Tsuchiya H, Osanai T, Sugita T, Sugiura H, Ieguchi M, Ihara K, Hamada K, Kakizaki H, Morii T, Yasuda T, Tanizawa T, Ogose A, Yabe H, Yamashita T, Sato N, Wada T
    Cancer science 103 1625-1630 2012年09月 [査読有り]
  • [Breast cancer stem cells].
    Yasuda K, Hirohashi Y, Torigoe T
    Nihon rinsho. Japanese journal of clinical medicine 70 Suppl 7 76-83 2012年09月 [査読有り]
  • Heat-shock proteins as endogenous ligands building a bridge between innate and adaptive immunity.
    Tamura Y, Torigoe T, Kukita K, Saito K, Okuya K, Kutomi G, Hirata K, Sato N
    Immunotherapy 4 841-852 2012年08月 [査読有り]
  • Gene expression profiles of prostate cancer stem cells isolated by aldehyde dehydrogenase activity assay.
    Nishida S, Hirohashi Y, Torigoe T, Kitamura H, Takahashi A, Masumori N, Tsukamoto T, Sato N
    The Journal of urology 188 294-299 2012年07月 [査読有り]
  • HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.
    Nishizawa S, Hirohashi Y, Torigoe T, Takahashi A, Tamura Y, Mori T, Kanaseki T, Kamiguchi K, Asanuma H, Morita R, Sokolovskaya A, Matsuzaki J, Yamada R, Fujii R, Kampinga HH, Kondo T, Hasegawa T, Hara I, Sato N
    Cancer research 72 2844-2854 2012年06月 [査読有り]
  • ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells.
    Matsuzaki J, Torigoe T, Hirohashi Y, Kamiguchi K, Tamura Y, Tsukahara T, Kubo T, Takahashi A, Nakazawa E, Saka E, Yasuda K, Takahashi S, Sato N
    Carcinogenesis 33 996-1003 2012年05月 [査読有り]
  • Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue: unusually high frequency of down-regulation in breast cancer tissues.
    Torigoe T, Asanuma H, Nakazawa E, Tamura Y, Hirohashi Y, Yamamoto E, Kanaseki T, Hasegawa T, Sato N
    Pathology international 62 303-308 2012年05月 [査読有り]
  • Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.
    Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Kondo T, Greene MI, Hara I, Sato N
    Experimental and molecular pathology 92 27-32 2012年02月 [査読有り]
  • Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses.
    Mizuuchi M, Hirohashi Y, Torigoe T, Kuroda T, Yasuda K, Shimizu Y, Saito T, Sato N
    Experimental and molecular pathology 92 185-190 2012年02月 [査読有り]
  • Cytotoxic T lymphocytes: Sniping cancer stem cells.
    Hirohashi Y, Torigoe T, Inoda S, Morita R, Kochin V, Sato N
    Oncoimmunology 1 123-125 2012年01月 [査読有り]
  • SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity.
    Nakatsugawa M, Takahashi A, Hirohashi Y, Torigoe T, Inoda S, Murase M, Asanuma H, Tamura Y, Morita R, Michifuri Y, Kondo T, Hasegawa T, Takahashi H, Sato N
    Laboratory investigation; a journal of technical methods and pathology 91 1796-1804 2011年12月 [査読有り]
  • Identification of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from the lung carcinoma antigen, Lengsin.
    Nakatsugawa M, Horie K, Yoshikawa T, Shimomura M, Kikuchi Y, Sakemura N, Suzuki S, Nobuoka D, Hirohashi Y, Torigoe T, Harada K, Takasu H, Sato N, Nakatsura T
    International journal of oncology 39 1041-1049 2011年10月 [査読有り]
  • Autologous CTL response against cancer stem-like cells/cancer-initiating cells of bone malignant fibrous histiocytoma.
    Kano M, Tsukahara T, Emori M, Murase M, Torigoe T, Kawaguchi S, Wada T, Yamashita T, Sato N
    Cancer science 102 1443-1447 2011年08月 [査読有り]
  • Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients.
    Kameshima H, Tsuruma T, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Ichimiya S, Kanaseki T, Iwayama Y, Sato N, Hirata K
    Cancer science 102 1181-1187 2011年06月 [査読有り]
  • Autoantibody against hypoxia-inducible factor prolyl hydroxylase-3 is a potential serological marker for renal cell carcinoma.
    Tanaka T, Kitamura H, Torigoe T, Hirohashi Y, Sato E, Masumori N, Sato N, Tsukamoto T
    Journal of cancer research and clinical oncology 137 789-794 2011年05月 [査読有り]
  • Tumor-produced secreted form of binding of immunoglobulin protein elicits antigen-specific tumor immunity.
    Tamura Y, Hirohashi Y, Kutomi G, Nakanishi K, Kamiguchi K, Torigoe T, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 186 4325-4330 2011年04月 [査読有り]
  • Prognostic significance of HLA class I expression in Ewing's sarcoma family of tumors.
    Yabe H, Tsukahara T, Kawaguchi S, Wada T, Torigoe T, Sato N, Terai C, Aoki M, Hirose S, Morioka H, Yabe H
    Journal of surgical oncology 103 380-385 2011年04月 [査読有り]
  • Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells.
    Oura J, Tamura Y, Kamiguchi K, Kutomi G, Sahara H, Torigoe T, Himi T, Sato N
    International immunology 23 223-237 2011年04月 [査読有り]
  • Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.
    Inoda S, Hirohashi Y, Torigoe T, Morita R, Takahashi A, Asanuma H, Nakatsugawa M, Nishizawa S, Tamura Y, Tsuruma T, Terui T, Kondo T, Ishitani K, Hasegawa T, Hirata K, Sato N
    The American journal of pathology 178 1805-1813 2011年04月 [査読有り]
  • The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma.
    Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N
    Experimental and molecular pathology 90 55-60 2011年02月 [査読有り]
  • Phase I clinical trial of survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer.
    Miyazaki A, Kobayashi J, Torigoe T, Hirohashi Y, Yamamoto T, Yamaguchi A, Asanuma H, Takahashi A, Michifuri Y, Nakamori K, Nagai I, Sato N, Hiratsuka H
    Cancer science 102 324-329 2011年02月 [査読有り]
  • Comparison of speedy PCR-ssp method and serological typing of HLA-A24 for Japanese cancer patients.
    Nakatsugawa M, Hirohashi Y, Torigoe T, Inoda S, Kiriyama K, Tamura Y, Sato E, Takahashi H, Sato N
    Journal of immunoassay & immunochemistry 32 93-102 2011年 [査読有り]
  • CD8+ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection.
    Yamada N, Oizumi S, Kikuchi E, Shinagawa N, Konishi-Sakakibara J, Ishimine A, Aoe K, Gemba K, Kishimoto T, Torigoe T, Nishimura M
    Cancer immunology, immunotherapy : CII 59 1543-1549 2010年10月 [査読有り]
  • Gimeracil sensitizes cells to radiation via inhibition of homologous recombination.
    Takagi M, Sakata K, Someya M, Tauchi H, Iijima K, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M, Fukushima M
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 96 259-266 2010年08月 [査読有り]
  • Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome.
    Okuya K, Tamura Y, Saito K, Kutomi G, Torigoe T, Hirata K, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 184 7092-7099 2010年06月 [査読有り]
  • Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells.
    Hirohashi Y, Torigoe T, Inoda S, Takahashi A, Morita R, Nishizawa S, Tamura Y, Suzuki H, Toyota M, Sato N
    Immunotherapy 2 201-211 2010年03月 [査読有り]
  • Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells.
    Hirohashi Y, Torigoe T, Hirai I, Tamura Y, Nakatsugawa M, Inoue Y, Kanaseki T, Kamiguchi K, Ikeda H, Sasaki A, Yamanaka N, Sato N
    Experimental and molecular pathology 88 128-132 2010年02月 [査読有り]
  • Human leukocyte antigen class I down-regulation in muscle-invasive bladder cancer: its association with clinical characteristics and survival after cystectomy.
    Homma I, Kitamura H, Torigoe T, Tanaka T, Sato E, Hirohashi Y, Masumori N, Sato N, Tsukamoto T
    Cancer science 100 2331-2334 2009年12月 [査読有り]
  • Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer.
    Honma I, Torigoe T, Hirohashi Y, Kitamura H, Sato E, Masumori N, Tamura Y, Tsukamoto T, Sato N
    Journal of translational medicine 7 103 2009年12月 [査読有り]
  • Heat shock proteins and immunity: application of hyperthermia for immunomodulation.
    Torigoe T, Tamura Y, Sato N
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 25 610-616 2009年12月 [査読有り]
  • Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer.
    Honma I, Kitamura H, Torigoe T, Takahashi A, Tanaka T, Sato E, Hirohashi Y, Masumori N, Tsukamoto T, Sato N
    Cancer immunology, immunotherapy : CII 58 1801-1807 2009年11月 [査読有り]
  • Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen-regulated protein 150-peptide complexes.
    Kutomi G, Tamura Y, Okuya K, Yamamoto T, Hirohashi Y, Kamiguchi K, Oura J, Saito K, Torigoe T, Ogawa S, Hirata K, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 183 5861-5869 2009年11月 [査読有り]
  • Novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4.
    Nakatsugawa M, Hirohashi Y, Torigoe T, Asanuma H, Takahashi A, Inoda S, Kiriyama K, Nakazawa E, Harada K, Takasu H, Tamura Y, Kamiguchi K, Shijubo N, Honda R, Nomura N, Hasegawa T, Takahashi H, Sato N
    Cancer science 100 1485-1493 2009年08月 [査読有り]
  • HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor.
    Tsukahara T, Kawaguchi S, Torigoe T, Takahashi A, Murase M, Kano M, Wada T, Kaya M, Nagoya S, Yamashita T, Sato N
    Journal of translational medicine 7 44 2009年06月 [査読有り]
  • Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma.
    Inoda S, Hirohashi Y, Torigoe T, Nakatsugawa M, Kiriyama K, Nakazawa E, Harada K, Takasu H, Tamura Y, Kamiguchi K, Asanuma H, Tsuruma T, Terui T, Ishitani K, Ohmura T, Wang Q, Greene MI, Hasegawa T, Hirata K, Sato N
    Journal of immunotherapy (Hagerstown, Md. : 1997) 32 474-485 2009年06月 [査読有り]
  • Immunosuppressive effect on T cell activation by interleukin-16- and interleukin-10-cDNA-double-transfected human squamous cell line.
    Matsumoto Y, Fujita T, Hirai I, Sahara H, Torigoe T, Ezoe K, Saito T, Cruikshank WW, Yotsuyanagi T, Sato N
    Burns : journal of the International Society for Burn Injuries 35 383-389 2009年05月 [査読有り]
  • The functioning antigens: beyond just as the immunological targets.
    Hirohashi Y, Torigoe T, Inoda S, Kobayasi J, Nakatsugawa M, Mori T, Hara I, Sato N
    Cancer science 100 798-806 2009年05月 [査読有り]
  • Mechanism of immune escape of cancer and its regulation.
    Morita R, Hirohashi Y, Torigoe T
    [Rinsho ketsueki] The Japanese journal of clinical hematology 50 375-380 2009年05月 [査読有り]
  • Molecular pathological approaches to human tumor immunology.
    Sato N, Hirohashi Y, Tsukahara T, Kikuchi T, Sahara H, Kamiguchi K, Ichimiya S, Tamura Y, Torigoe T
    Pathology international 59 205-217 2009年04月 [査読有り]
  • Polyamine compound deoxyspergualin inhibits heat shock protein-induced activation of immature dendritic cells.
    Sugawara A, Torigoe T, Tamura Y, Kamiguchi K, Nemoto K, Oguro H, Sato N
    Cell stress & chaperones 14 133-139 2009年03月 [査読有り]
  • Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma.
    Kobayashi J, Hirohashi Y, Torigoe T, Michifuri Y, Yamamoto T, Tamura Y, Kamiguchi K, Miyazaki A, Yamaguchi A, Hariu H, Hiratsuka H, Sato N
    Human immunology 70 89-95 2009年02月 [査読有り]
  • Concomitant overexpression of heat-shock protein 70 and HLA class-I in hepatitis C virus-related hepatocellular carcinoma.
    Yoshida S, Hazama S, Tokuno K, Sakamoto K, Takashima M, Tamesa T, Torigoe T, Sato N, Oka M
    Anticancer research 29 539-544 2009年02月 [査読有り]
  • Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma.
    Tsukahara T, Kimura S, Ichimiya S, Torigoe T, Kawaguchi S, Wada T, Yamashita T, Sato N
    Cancer science 100 47-53 2009年01月 [査読有り]
  • Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients.
    Kobayashi J, Torigoe T, Hirohashi Y, Idenoue S, Miyazaki A, Yamaguchi A, Hiratsuka H, Sato N
    Journal of translational medicine 7 1 2009年01月 [査読有り]
  • Gene expression profile of dorsal root ganglion in a lumbar radiculopathy model.
    Takeuchi H, Kawaguchi S, Mizuno S, Kirita T, Takebayashi T, Shimozawa K, Torigoe T, Sato N, Yamashita T
    Spine 33 2483-2488 2008年11月 [査読有り]
  • Identification of an immunogenic CTL epitope of HIFPH3 for immunotherapy of renal cell carcinoma.
    Sato E, Torigoe T, Hirohashi Y, Kitamura H, Tanaka T, Honma I, Asanuma H, Harada K, Takasu H, Masumori N, Ito N, Hasegawa T, Tsukamoto T, Sato N
    Clinical cancer research : an official journal of the American Association for Cancer Research 14 6916-6923 2008年11月 [査読有り]
  • Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation.
    Bagnall RD, Roberts RG, Mirza MM, Torigoe T, Prescott NJ, Mathew CG
    European journal of human genetics : EJHG 16 619-625 2008年05月 [査読有り]
  • Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer.
    Tsuruma T, Iwayama Y, Ohmura T, Katsuramaki T, Hata F, Furuhata T, Yamaguchi K, Kimura Y, Torigoe T, Toyota N, Yagihashi A, Hirohashi Y, Asanuma H, Shimozawa K, Okazaki M, Mizushima Y, Nomura N, Sato N, Hirata K
    Journal of translational medicine 6 24 2008年05月 [査読有り]
  • Clonal T-cell response against autologous pleomorphic malignant fibrous histiocytoma antigen presented by retrieved HLA-A*0206.
    Kimura S, Kozakai Y, Kawaguchi S, Tsukahara T, Ida K, Murase M, Matsumura T, Kaya M, Torigoe T, Wada T, Sato N, Yamashita T
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society 26 271-278 2008年02月 [査読有り]
  • Prognostic impact and immunogenicity of a novel osteosarcoma antigen, papillomavirus binding factor, in patients with osteosarcoma.
    Tsukahara T, Kawaguchi S, Torigoe T, Kimura S, Murase M, Ichimiya S, Wada T, Kaya M, Nagoya S, Ishii T, Tatezaki S, Yamashita T, Sato N
    Cancer science 99 368-375 2008年02月 [査読有り]
  • Disruption of the association of 73 kDa heat shock cognate protein with transporters associated with antigen processing (TAP) decreases TAP-dependent translocation of antigenic peptides into the endoplasmic reticulum.
    Kamiguchi K, Torigoe T, Fujiwara O, Ohshima S, Hirohashi Y, Sahara H, Hirai I, Kohgo Y, Sato N
    Microbiology and immunology 52 94-106 2008年02月 [査読有り]
  • HLA class I antigen expression is associated with a favorable prognosis in early stage non-small cell lung cancer.
    Kikuchi E, Yamazaki K, Torigoe T, Cho Y, Miyamoto M, Oizumi S, Hommura F, Dosaka-Akita H, Nishimura M
    Cancer science 98 1424-1430 2007年09月 [査読有り]
  • Down-regulation of HLA class I antigens in prostate cancer tissues and up-regulation by histone deacetylase inhibition.
    Kitamura H, Torigoe T, Asanuma H, Honma I, Sato N, Tsukamoto T
    The Journal of urology 178 692-696 2007年08月 [査読有り]
  • Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway.
    Kurotaki T, Tamura Y, Ueda G, Oura J, Kutomi G, Hirohashi Y, Sahara H, Torigoe T, Hiratsuka H, Sunakawa H, Hirata K, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 179 1803-1813 2007年08月 [査読有り]
  • Expression of livin in renal cell carcinoma and detection of anti-livin autoantibody in patients.
    Kitamura H, Honma I, Torigoe T, Hariu H, Asanuma H, Hirohashi Y, Sato E, Sato N, Tsukamoto T
    Urology 70 38-42 2007年07月 [査読有り]
  • Down-regulation of HLA class I antigen is an independent prognostic factor for clear cell renal cell carcinoma.
    Kitamura H, Honma I, Torigoe T, Asanuma H, Sato N, Tsukamoto T
    The Journal of urology 177 1269-72; discussion 1272 2007年04月 [査読有り]
  • Plasma neuropeptides in patients undergoing lumbar discectomy.
    Takeuchi H, Kawaguchi S, Ohwada O, Kobayashi H, Hayakawa M, Takebayashi T, Torigoe T, Sato N, Yamashita T
    Spine 32 E79-84 2007年01月 [査読有り]
  • Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5.
    Tsukahara T, Kawaguchi S, Torigoe T, Asanuma H, Nakazawa E, Shimozawa K, Nabeta Y, Kimura S, Kaya M, Nagoya S, Wada T, Yamashita T, Sato N
    Cancer science 97 1374-1380 2006年12月 [査読有り]
  • Effect of human leukocyte antigen class I expression of tumor cells on outcome of intravesical instillation of bacillus calmette-guerin immunotherapy for bladder cancer.
    Kitamura H, Torigoe T, Honma I, Sato E, Asanuma H, Hirohashi Y, Sato N, Tsukamoto T
    Clinical cancer research : an official journal of the American Association for Cancer Research 12 4641-4644 2006年08月 [査読有り]
  • Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: implications for specific immunotherapy.
    Kitamura H, Torigoe T, Honma I, Asanuma H, Nakazawa E, Shimozawa K, Hirohashi Y, Sato E, Sato N, Tsukamoto T
    Urology 67 955-959 2006年05月 [査読有り]
  • Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma.
    Komori H, Nakatsura T, Senju S, Yoshitake Y, Motomura Y, Ikuta Y, Fukuma D, Yokomine K, Harao M, Beppu T, Matsui M, Torigoe T, Sato N, Baba H, Nishimura Y
    Clinical cancer research : an official journal of the American Association for Cancer Research 12 2689-2697 2006年05月 [査読有り]
  • HLA-restricted specific tumor cytolysis by autologous T-lymphocytes infiltrating metastatic bone malignant fibrous histiocytoma of lymph node.
    Tsukahara T, Kawaguchi S, Ida K, Kimura S, Tamura Y, Ikeda T, Torigoe T, Nagoya S, Wada T, Sato N, Yamashita T
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society 24 94-101 2006年01月 [査読有り]
  • Basaloid carcinoma of the thymus: report of a case.
    Morisaki Y, Takagi K, Sano S, Furuya T, Ishikawa M, Torigoe T, Ishii Y
    Surgery today 36 68-70 2006年 [査読有り]
  • Detection of autoantibodies to survivin and livin in sera from patients with breast cancer.
    Yagihashi A, Ohmura T, Asanuma K, Kobayashi D, Tsuji N, Torigoe T, Sato N, Hirata K, Watanabe N
    Clinica chimica acta; international journal of clinical chemistry 362 125-130 2005年12月 [査読有り]
  • Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.
    Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, Sato N
    Cancer research 65 11018-11025 2005年12月 [査読有り]
  • A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis.
    Yamamoto M, Torigoe T, Kamiguchi K, Hirohashi Y, Nakanishi K, Nabeta C, Asanuma H, Tsuruma T, Sato T, Hata F, Ohmura T, Yamaguchi K, Kurotaki T, Hirata K, Sato N
    Cancer research 65 8706-8714 2005年10月 [査読有り]
  • Autoantibodies to survivin in patients with chronic hepatitis and hepatocellular carcinoma.
    Yagihashi A, Asanuma K, Kobayashi D, Tsuji N, Torigoe T, Sato N, Watanabe N
    Autoimmunity 38 445-448 2005年09月 [査読有り]
  • A quest for therapeutic antigens in bone and soft tissue sarcoma.
    Kawaguchi S, Wada T, Tsukahara T, Ida K, Torigoe T, Sato N, Yamashita T
    Journal of translational medicine 3 31 2005年08月 [査読有り]
  • Peptide-based vaccination for colorectal cancer.
    Tsuruma T, Hata F, Furuhata T, Ohmura T, Katsuramaki T, Yamaguchi K, Kimura Y, Torigoe T, Sato N, Hirata K
    Expert opinion on biological therapy 5 799-807 2005年06月 [査読有り]
  • Detection of autoantibodies to livin and survivin in Sera from lung cancer patients.
    Yagihashi A, Asanuma K, Kobayashi D, Tsuji N, Shijubo Y, Abe S, Hirohashi Y, Torigoe T, Sato N, Watanabe N
    Lung cancer (Amsterdam, Netherlands) 48 217-221 2005年05月 [査読有り]
  • Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer.
    Hariu H, Hirohashi Y, Torigoe T, Asanuma H, Hariu M, Tamura Y, Aketa K, Nabeta C, Nakanishi K, Kamiguchi K, Mano Y, Kitamura H, Kobayashi J, Tsukahara T, Shijubo N, Sato N
    Clinical cancer research : an official journal of the American Association for Cancer Research 11 1000-1009 2005年02月 [査読有り]
  • A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins.
    Idenoue S, Hirohashi Y, Torigoe T, Sato Y, Tamura Y, Hariu H, Yamamoto M, Kurotaki T, Tsuruma T, Asanuma H, Kanaseki T, Ikeda H, Kashiwagi K, Okazaki M, Sasaki K, Sato T, Ohmura T, Hata F, Yamaguchi K, Hirata K, Sato N
    Clinical cancer research : an official journal of the American Association for Cancer Research 11 1474-1482 2005年02月 [査読有り]
  • Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma.
    Kawaguchi S, Wada T, Ida K, Sato Y, Nagoya S, Tsukahara T, Kimura S, Sahara H, Ikeda H, Shimozawa K, Asanuma H, Torigoe T, Hiraga H, Ishii T, Tatezaki SI, Sato N, Yamashita T
    Journal of translational medicine 3 1 2005年01月 [査読有り]
  • A calcium binding protein, S100A4, mediates T cell dependent cytotoxicity as a transformation-associated antigen.
    Kondo N, Ichimiya S, Tamura Y, Tonooka A, Koshiba S, Torigoe T, Kamiguchi K, Takenaga K, Sato N
    Microbiology and immunology 49 49-56 2005年 [査読有り]
  • [Anti-apoptosis protein, survivin-2B-derived peptide vaccine therapy].
    Tsuruma T, Torigoe T, Hata F, Furuhata T, Sato N, Hirata K
    Gan to kagaku ryoho. Cancer & chemotherapy 31 1634-1636 2004年10月 [査読有り]
  • Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor.
    Tsukahara T, Nabeta Y, Kawaguchi S, Ikeda H, Sato Y, Shimozawa K, Ida K, Asanuma H, Hirohashi Y, Torigoe T, Hiraga H, Nagoya S, Wada T, Yamashita T, Sato N
    Cancer research 64 5442-5448 2004年08月 [査読有り]
  • Crisscross CTL induction by SYT-SSX junction peptide and its HLA-A*2402 anchor substitute.
    Ida K, Kawaguchi S, Sato Y, Tsukahara T, Nabeta Y, Sahara H, Ikeda H, Torigoe T, Ichimiya S, Kamiguchi K, Wada T, Nagoya S, Hiraga H, Kawai A, Ishii T, Araki N, Myoui A, Matsumoto S, Ozaki T, Yoshikawa H, Yamashita T, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 173 1436-1443 2004年07月 [査読有り]
  • Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer.
    Tsuruma T, Hata F, Torigoe T, Furuhata T, Idenoue S, Kurotaki T, Yamamoto M, Yagihashi A, Ohmura T, Yamaguchi K, Katsuramaki T, Yasoshima T, Sasaki K, Mizushima Y, Minamida H, Kimura H, Akiyama M, Hirohashi Y, Asanuma H, Tamura Y, Shimozawa K, Sato N, Hirata K
    Journal of translational medicine 2 19 2004年06月 [査読有り]
  • [Immunoregulatory role of the protein quality control system].
    Tamura Y, Torigoe T
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 49 1023-1026 2004年05月 [査読有り]
  • Tumor-derived heat shock protein 70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity.
    Ueda G, Tamura Y, Hirai I, Kamiguchi K, Ichimiya S, Torigoe T, Hiratsuka H, Sunakawa H, Sato N
    Cancer science 95 248-253 2004年03月 [査読有り]
  • Survivin as a predictor of cis-diamminedichloroplatinum sensitivity in gastric cancer patients.
    Nakamura M, Tsuji N, Asanuma K, Kobayashi D, Yagihashi A, Hirata K, Torigoe T, Sato N, Watanabe N
    Cancer science 95 44-51 2004年01月 [査読有り]
  • Localization and function in endoplasmic reticulum stress tolerance of ERdj3, a new member of Hsp40 family protein.
    Nakanishi K, Kamiguchi K, Torigoe T, Nabeta C, Hirohashi Y, Asanuma H, Tobioka H, Koge N, Harada O, Tamura Y, Nagano H, Yano S, Chiba S, Matsumoto H, Sato N
    Cell stress & chaperones 9 253-264 2004年 [査読有り]
  • Histone H2AX sensitizes glioma cells to genotoxic stimuli by recruiting DNA double-strand break repair proteins.
    Momota H, Ichimiya S, Kondo N, Kikuchi T, Torigoe T, Yamaki T, Houkin K, Sato N
    International journal of oncology 23 311-315 2003年08月 [査読有り]
  • Detection of anti-livin antibody in gastrointestinal cancer patients.
    Yagihashi A, Asanuma K, Tsuji N, Torigoe T, Sato N, Hirata K, Watanabe N
    Clinical chemistry 49 1206-1208 2003年07月 [査読有り]
  • [Current and future aspects of human tumor immunotherapy].
    Sato N, Ikeda H, Tamura Y, Sahara H, Torigoe T
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science 78 7-9 2003年01月 [査読有り]
  • T-cell receptor variable gamma chain gene expression in the interaction between rat gammadelta-type T cells and heat-shock protein 70-like molecule.
    Ichinohe T, Ichimiya S, Kishi A, Tamura Y, Kondo N, Ueda G, Torigoe T, Yamaguchi A, Hiratsuka H, Hirai I, Kohama GI, Sato N
    Microbiology and immunology 47 351-357 2003年 [査読有り]
  • Recognition by cellular and humoral autologous immunity in a human osteosarcoma cell line.
    Nabeta Y, Kawaguchi S, Sahara H, Ikeda H, Hirohashi Y, Goroku T, Sato Y, Tsukahara T, Torigoe T, Wada T, Kaya M, Hiraga H, Isu K, Yamawaki S, Ishii S, Yamashita T, Sato N
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 8 554-559 2003年 [査読有り]
  • Improved generation of HLA class I/peptide tetramers.
    Sato Y, Sahara H, Tsukahara T, Kondo M, Hirohashi Y, Nabeta Y, Kawaguchi S, Ikeda H, Torigoe T, Ichimiya S, Tamura Y, Wada T, Yamashita T, Goto M, Takasu H, Sato N
    Journal of immunological methods 271 177-184 2002年12月 [査読有り]
  • Detection and induction of CTLs specific for SYT-SSX-derived peptides in HLA-A24(+) patients with synovial sarcoma.
    Sato Y, Nabeta Y, Tsukahara T, Hirohashi Y, Syunsui R, Maeda A, Sahara H, Ikeda H, Torigoe T, Ichimiya S, Wada T, Yamashita T, Hiraga H, Kawai A, Ishii T, Araki N, Myoui A, Matsumoto S, Umeda T, Ishii S, Kawaguchi S, Sato N
    Journal of immunology (Baltimore, Md. : 1950) 169 1611-1618 2002年08月 [査読有り]
  • Natural antigenic peptides from squamous cell carcinoma recognized by autologous HLA-DR8-restricted CD4+ T cells.
    Kondo H, Sahara H, Miyazaki A, Nabeta Y, Hirohashi Y, Kanaseki T, Yamaguchi A, Yamada N, Hirayama K, Suzuki M, Hamuro J, Torigoe T, Takahashi N, Kohama GI, Ikeda H, Sato N
    Japanese journal of cancer research : Gann 93 917-924 2002年08月 [査読有り]
  • An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin.
    Hirohashi Y, Torigoe T, Maeda A, Nabeta Y, Kamiguchi K, Sato T, Yoda J, Ikeda H, Hirata K, Yamanaka N, Sato N
    Clinical cancer research : an official journal of the American Association for Cancer Research 8 1731-1739 2002年06月 [査読有り]
  • A gene encoding human gastric signet ring cell carcinoma antigen recognized by HLA-A31-restricted cytotoxic T lymphocytes.
    Sahara H, Nabeta Y, Torigoe T, Hirohashi Y, Ichimiya S, Wada Y, Takahashi N, Jimbow K, Yajima T, Watanabe N, Kikuchi K, Sato N
    Journal of immunotherapy (Hagerstown, Md. : 1997) 25 235-242 2002年05月 [査読有り]
  • Identification of germline mutation of PTEN gene and analysis of apoptosis resistance of the lymphocytes in a patient with Cowden disease.
    Kanaseki T, Torigoe T, Hirohashi Y, Hirai I, Himi T, Sato N
    Pathobiology : journal of immunopathology, molecular and cellular biology 70 34-39 2002年 [査読有り]

MISC

  • 分子シャペロン
    病理診断における分子生物学 22 69-74 2004年
  • 蛋白質品質管理システムによる免疫制御
    細胞における蛋白質の一生:生成・成熟・輸送・管理・分解・病態 49 1023-6 2004年
  • 腫瘍免疫標的抗原としてのアポトーシス阻止因子(IAP)
    臨床免疫 41 9999-9999 2004年
  • 札幌医大が発するヒト癌免疫の基礎研究
    札幌医科大学研究フォーラム 2004年
  • 癌の免疫エスケープメカニズム
    Annual Review 免疫2004 2003年
  • 癌転移と免疫逃避
    医学のあゆみ ”浸潤・転移の分子メカニズム” 206 256-260 2003年
  • An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin.
    Matsumoto Y, Sahara H, Fujita T, Shimozawa K, Takenouchi M, Torigoe T, Hanashima S, Yamazaki T, Takahashi S, Sugawara F, Mizushina Y, Ohta K, Takahashi N, Gasa S, Jimbow K, Sakaguchi K, Sato N
    Transplantation 74 261-267 2002年07月 [査読有り]
  • Chemokine profile of herniated intervertebral discs infiltrated with monocytes and macrophages.
    Kawaguchi S, Yamashita T, Katahira G, Yokozawa H, Torigoe T, Sato N
    Spine 27 1511-1516 2002年07月 [査読有り]
  • アルツハイマー病,プリオン病に対する免疫療法
    Annual Review 免疫2003 2002年
  • 自然流産とその免疫学的機構,関与
    Annual Review 免疫2003 2002年
MISCを全て表示する
  • 分子シャペロン
    病理診断における分子生物学 22 69-74 2004年
  • 蛋白質品質管理システムによる免疫制御
    細胞における蛋白質の一生:生成・成熟・輸送・管理・分解・病態 49 1023-6 2004年
  • 腫瘍免疫標的抗原としてのアポトーシス阻止因子(IAP)
    臨床免疫 41 9999-9999 2004年
  • 札幌医大が発するヒト癌免疫の基礎研究
    札幌医科大学研究フォーラム 2004年
  • 癌の免疫エスケープメカニズム
    Annual Review 免疫2004 2003年
  • 癌転移と免疫逃避
    医学のあゆみ ”浸潤・転移の分子メカニズム” 206 256-260 2003年
  • An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin.
    Matsumoto Y, Sahara H, Fujita T, Shimozawa K, Takenouchi M, Torigoe T, Hanashima S, Yamazaki T, Takahashi S, Sugawara F, Mizushina Y, Ohta K, Takahashi N, Gasa S, Jimbow K, Sakaguchi K, Sato N
    Transplantation 74 261-267 2002年07月 [査読有り]
  • Chemokine profile of herniated intervertebral discs infiltrated with monocytes and macrophages.
    Kawaguchi S, Yamashita T, Katahira G, Yokozawa H, Torigoe T, Sato N
    Spine 27 1511-1516 2002年07月 [査読有り]
  • アルツハイマー病,プリオン病に対する免疫療法
    Annual Review 免疫2003 2002年
  • 自然流産とその免疫学的機構,関与
    Annual Review 免疫2003 2002年
  • シグナル伝達と薬剤耐性
    臨床病理レビュー 119 71-79 2002年
  • 分子シャペロンと病態 − 4.抗原ペプチド
    分子シャペロンによる細胞機能制御 2002年
  • アポトーシスと癌 なぜ癌になるのか?(2)
    21世紀の癌医療と先端研究セミナーシリーズ 2002年
  • 細胞周期関連分子
    生体機能分子データブック 2001年
  • 腫瘍免疫とリンパ節転移
    リンパ学 24 7-8 2001年
  • ヒト癌免疫の分子基盤と癌免疫治療,癌ワクチン
    耳鼻免疫アレルギー 19 32-38 2001年
  • 腫瘍免疫におけるストレス蛋白質−抗原としてシャペロンとして−
    Annual Review 免疫2000 2000年
  • Mild Hypothermia からの復温期に認められるT細胞活性化の過敏症 
    バイオメディカル -救急集中治療領域におけるDIC- 10 55-65 2000年
  • ヒト癌免疫治療の分子基盤と展望
    腎癌研究会会報 19 19-23 2000年
  • MHC class I抗原提示機構におけるTAP依存性ペプチド転送機能の解析 −ペプチドによる至適条件の違いについて−
    札幌医誌 68 21-29 1999年
  • 深海微生物の環境適応−圧力応答とコールドショック応答−
    Bull. Marine Biomed. Inst. Sapporo Med. Univ. 4 55-59 1999年
  • T細胞における細胞周期制御の分子機構
    Annual Review 免疫1998 1998年
  • 熱ショック蛋白質と腫瘍免疫
    日本ショック学会誌 13 49-53 1998年
  • ウイルスによる抗原処理、提示の抑制
    臨床免疫 30 1318-1324 1998年
  • 抗原ペプチドシャペロンとしてのストレス蛋白質
    医学のあゆみ 187 235-239 1998年
  • 細胞内シグナル伝達機構と免疫
    周り道免疫学 1998年
  • MHC class I抗原発現に関わる分子シャペロン
    臨床免疫 30 1607-1612 1998年
  • 胃炎のSydney Systemについて
    自札幌病年報 39 1-10 1998年
  • 癌拒絶,抗原提示機構とHSP
    佐藤 昇志, 鳥越 俊彦, 菊地 浩吉
    炎症 17(3) 269-273 1997年
  • 抗原ペプチドの輸送に関わる分子群
    臨床免疫 29 519-524 1997年
  • 網膜芽細胞腫蛋白質における73kDa熱ショック蛋白質会合部位の同定と分子会合の機能的意義の解析
    札幌医誌 66 19-27 1997年
  • IL-10による腫瘍免疫の抑制
    臨床免疫 29 1108-1114 1997年
  • HSPによる抗原ペプチドの転送
    臨床免疫 29 1131-1137 1997年
  • Interleukin-10による主要組織適合抗原および腫瘍関連抗原の調節
    札幌医誌 66 1-8 1997年
  • リンパ球における細胞増殖と細胞死制御の分子機構
    自札幌病年報 38 9-14 1997年
  • 間質樹状細胞とその腫瘍の多様性
    自札幌病年報 38 1-7 1997年
  • ウイルスと宿主の戦い;抗原処理提示機構とウイルスの免疫逃避機構
    自札幌病年報 38 15-20 1997年

競争的資金等の研究課題

  • 免疫系による腫瘍拒絶機構の解明と癌免疫治療の開発
  • ストレス蛋白質による免疫制御
  • 神経筋変性疾患の病態形成における分子シャペロンの役割
  • 微小重力環境の細胞生物学
競争的資金等の研究課題を全て表示する
競争的資金等の研究課題閉じる
  • 免疫系による腫瘍拒絶機構の解明と癌免疫治療の開発
  • ストレス蛋白質による免疫制御
  • 神経筋変性疾患の病態形成における分子シャペロンの役割
  • 微小重力環境の細胞生物学

受賞

  • 2014年 小野がん研究財団 研究助成
  • 2014年 ノーステック財団 研究開発助成
  • 2007年10月 日本病理学会 学術研究賞
  • 2002年 大阪癌研究会研究助成
  • 2000年 日本宇宙フォーラム地上研究助成
  • 1999年 秋山記念生命科学振興財団
  • 1997年 伊藤医薬学術交流財団
受賞を全て表示する
受賞閉じる
  • 2014年 小野がん研究財団 研究助成
  • 2014年 ノーステック財団 研究開発助成
  • 2007年10月 日本病理学会 学術研究賞
  • 2002年 大阪癌研究会研究助成
  • 2000年 日本宇宙フォーラム地上研究助成
  • 1999年 秋山記念生命科学振興財団
  • 1997年 伊藤医薬学術交流財団


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