研究者詳細 - 堀口　雅美

論文 - 堀口　雅美

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ガスクロマトグラフィー質量分析を用いた患者の皮膚病変部に由来する臭気成分候補の探索

飯澤良祐, 堀口雅美, 宇原久, 菅裕司, 冨樫邦弘, 鈴木誠, 野村隆文, 板垣史郎, 宇野智子, 中村円

におい・かおり環境学会誌 ( 公益社団法人におい・かおり環境協会 ) 55 ( 5 ) 315 - 318 2024年09月

本研究は，ガスクロマトグラフィー質量分析（以下，GC-MS法）を用いて，入院患者の皮膚病変部に貼付した被覆材から臭気成分を検出できるか検討した．その結果，皮膚病変部の被覆材から悪臭に分類されるAcetoin，Acetol，Diacetyl，Isovaleric acidが定性候補成分として検出された．以上より，GC-MS法は皮膚病変部の被覆材に付着した臭気成分の検出に適用できることが示唆された．

DOI

COVID-19感染拡大により遠隔代理実践を導入した看護技術総合演習に関する教育実践報告

中村円, 宇野智子, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 99 - 103 2022年03月 [査読有り]

COVID-19感染拡大により学内実習に変更した基礎看護実習1に関する教育実践報告

飯澤良祐, 宇野智子, 中村円, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 93 - 97 2022年03月 [査読有り]

COVID-19感染拡大により学内実習に変更した基礎看護実習2に関する教育実践報告

宇野智子, 中村円, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 87 - 91 2022年03月 [査読有り]

Association between chronic psychosocial stress and the finger arterial stiffness mediated by an allostatic load in healthy young men

Gohichi Tanaka, Masami Horiguchi, Hisayoshi Okamura, Yuichi Kato, Akira Tsuda

Chronic Stress and Health ( Nova Science Publishers, Inc. ) 1 - 32 2017年01月

Allostatic load (AL) describes how chronic psychosocial stress relates to health outcomes. Stiffening of the small artery may be a useful preclinical criterion of AL that indicates the earliest sign of arteriosclerosis. A novel and blood pressure independent index of finger arterial stiffness (FSI Tanaka et al., 2011), along with the cardiac-ankle vascular index (CAVI) as a measure of large artery stiffness, were measured in two different age groups of Japanese asymptomatic young men: those over 23 (O23 mean age, 25.5 ± 3.3 n = 78) and those under 22 (U22 mean age, 20.0 ± 1.3 n = 292) years of age. Arterial stiffness measures were compared in terms of their relationship with AL summary index (ALI), which was defined by the mean of standard scores for 10 variables: body mass index, body fat, systolic and diastolic blood pressure, high-density lipoprotein cholesterol (HDL), total cholesterol/HDL ratio, triglycerides, hemoglobin A1c, homeostasis model assessment-insulin resistance, and Creactive protein. Furthermore, we compared the association of ALI with lifestyle and stress-related psychosocial factors between the groups. ALI and CAVI were significantly higher in the O23 group than in the U22 group (ALI: t = 3.65, p < .01 CAVI: t = 6.15, p < .01), whereas FSI was not (t = 0.61, ns). Nevertheless, regarding the association with ALI after the adjustment for participant age, a partial correlation was significant between FSI and ALI in the O23 group (partial r = .379, p < .01) but not between ALI and CAVI. There were no partial correlations between ALI and either stiffness measure in the U22 group. Stepwise multiple regression analyses excluding smokers revealed that ALI was significantly explained by the psychosocial measures: Anger Control-Out scale in State-Trait Anger Expression Inventory-2 (β = -391), age β= .383), and Meaningfulness scale in Sense of Coherence (β = -306) for the O23 group (adjusted R2 = .330 n = 59) by eating quickly (β = .214) and liking strong taste (β =163) in the Eating Behavior Scale and the time spent exercising per week (β = -179) for the U22 group (adjusted R2 = .102 n = 231). In conclusion, our results demonstrate the superiority of FSI to CAVI as an indicator of the early sign of arteriosclerosis mediated by chronic psychosocial stress. ALI and FSI were progressively associated with advancing age in the asymptomatic young men. Furthermore, ALI was differentially associated with psychosocial and lifestyle factors in the two age groups via different kinds of stress-coping strategies. The present findings suggest that a multisystem AL is a mediator linking psychosocial chronic stress to an exacerbation of small arterial stiffness. FSI is likely to be useful for investigating the comprehensive and progressive nature of the early stage of chronic stress-arteriosclerosis linkage.

GENDER-BASED RELATIONSHIP BETWEEN EATING BEHAVIOR AND SENSE OF COHERENCE IN JAPANESE YOUNG ADULTS

Masami Horiguchi, Gohichi Tanaka, Haruko Ogasawara, Ryoko Maruyama

SOCIAL BEHAVIOR AND PERSONALITY ( SOC PERSONALITY RES INC ) 44 ( 1 ) 45 - 58 2016年 [査読有り]

Eating behavior is affected by stress and sense of coherence (SOC), the latter of which is reflective of one's stress coping ability. Our objective in this study was to establish the gender-based relationship between the Eating Behavior Scale (EBS) and SOC. Participants were 334 Japanese undergraduate students. Overall scores on the 13-item SOC Scale (SOC-13) were higher for women than for men. There were significant negative correlations between EBS and SOC-13 scores for men, and a nonsignificant correlation between EBS and SOC-13 scores for women. Results of the correlation analyses indicated that there are gender-based differences in the relationship between eating behavior and SOC. Unhealthy eating behavior in men was associated with low stress coping ability; however, there was no such association in women.

DOI

Nurse odor perception in various Japanese hospital settings

Masami Horiguchi, Erika Shudo, Kumiko Sato, Madoka Nakamura, Wakana Sai, Terumi Ohinata

International Journal of Nursing Sciences ( Chinese Nursing Association ) 2 ( 4 ) 355 - 360 2015年12月 [査読有り]

Because unpleasant hospital odors affect the nursing environment, we investigated nurses' perceptions of the odors of various hospital settings: hospital rooms, nurse stations, and human waste disposal rooms to discard the urine, stools and diapers. A questionnaire based on the Japanese Ministry of the Environment's guidelines on odor index regulation was used to assess nurses' perceptions of odor intensity, comfort, tolerability, and description in the aforementioned settings. Questionnaires were distributed to nursing department directors at three Japanese hospitals, who then disseminated the questionnaires to nursing staff. Of the 1,151 questionnaires distributed, 496 nurses participated. Human waste disposal rooms had greater odor intensity and were perceived as more uncomfortable than the other settings. Unpleasant odors in disposal rooms, hospital rooms, and nurse stations were rated as slightly intolerable in comparison. Hospital and disposal rooms were mainly described as having a "pungent odor such as of urine and stool." In contrast, nurse stations were described as having other unpleasant odors, such as chemical, human-body-related, or sewage-like odors. Given that nurses spend much of their time in hospital rooms and nurse stations, odor management in these two settings would likely improve nurses' working conditions at hospitals. Improving odors at nurse stations is feasible. Such improvements could have indirect effects on nurse turnover and burnout.

DOI

Validation and Gender-Based Comparison of the Eating Behavior Scale for Japanese Young Adults

Horiguchi Masami, Gohichi Tanaka, Haruko Ogasawara, Ryoko Maruyama

Psychology 5 ( 19 ) 2173 - 2179 2014年12月 [査読有り]

DOI

Analysis of allostatic load and eating behaviors among healthy young women with different body types

Horiguchi Masami, Maruyama Ryoko, Tanaka Gohichi

FASEB JOURNAL 27 2013年04月 [査読有り]

医学生における抑うつ傾向と生活習慣病危険因子についての検討―インスリン抵抗性および低血圧との関連性―

小笠原晴子, 田中豪一, 堀口雅美, 河口明人

健康心理学研究 ( (一社)日本健康心理学会 ) 24 ( 2 ) 42 - 49 2012年03月 [査読有り]

DOI J-GLOBAL

A novel photoplethysmography technique to derive normalized arterial stiffness as a blood pressure independent measure in the finger vascular bed

Gohichi Tanaka, Ken-ichi Yamakoshi, Yukihiro Sawada, Kenta Matsumura, Kimihito Maeda, Yuichi Kato, Masami Horiguchi, Hiroshi Ohguro

PHYSIOLOGICAL MEASUREMENT ( IOP PUBLISHING LTD ) 32 ( 11 ) 1869 - 1883 2011年11月 [査読有り]

Stiffening of the small artery may be the earliest sign of arteriosclerosis. However, there is no adequate method for directly assessing small arterial stiffness. In this study, the finger arterial elasticity index (FEI) was defined as the parameter n which denotes the curvilinearity of an exponential model of pressure (P)-volume (V(a)) relationship (V(a) = a - b exp (-nP)). For the original estimation, the FEI was calculated from a compliance index from the finger photoplethysmogram whilst occluding the finger. A simple estimation of the FEI was devised by utilizing normalized pulse volume instead of the compliance index. Both estimations yielded close agreement with the exponential model in healthy young participants (study 1: n = 19). Since the FEI was dependent on finger mean blood pressure, normalized finger arterial stiffness index (FSI) was defined as standardized residual from their relationship: mean and standard deviation (SD) of the FSI were 50 +/- 10 (study 2: n = 174). The mean coefficient of variation of the FSI for four measurements was 5.72% (study 3: n = 6). The mean and SD of the FSI in seven arteriosclerotic patients were 100.0 +/- 13.5. In conclusion, the FEI and FSI by simple estimation are valid and useful for arteriosclerosis research.

DOI PubMed

The association between chronic psychosocial stress, allostatic load, and vascular health in asymptomatic young men: A pilot study using a novel finger arterial stiffness index

Gohichi Tanaka, Yuichi Kato, Kenta Matsumura, Masami Horiguchi, Haruko Ogasawara, Yukihiro Sawada

JAPANESE PSYCHOLOGICAL RESEARCH ( WILEY ) 53 ( 2 ) 140 - 154 2011年05月 [査読有り]

A novel index of finger arterial stiffness (FSI) was tested in terms of the relationship with risk markers for preclinical cardiovascular disease. In addition, we examined if the association between psychosocial factors and FSI was explained by allostatic load markers in 37 healthy young men aged 24.8 +/- 4.0 years. The FSI was devised based on an exponential model of the finger arterial pressure-volume relationship. The allostatic load index (ALI) as a cumulative risk marker was defined by the mean of standard scores for nine variables: resting systolic and diastolic blood pressure, waist/hip ratio, high-density lipoprotein cholesterol (HDL-C), total cholesterol/HDL-C ratio, triglycerides, hemoglobin A1c, insulin resistance, and high sensitivity C-reactive protein (CRP). Partial correlations controlling for age were significant for FSI with HDL-C (r = -.36), CRP (r = .39), ALI (r = .40), unhealthy overall eating habits (r = .34), hostility using the Buss-Perry Aggression Questionnaire (r = .38), and manageability in Sense of Coherence (r = -.38). In conclusion, FSI seems to be associated with vascular proinflammation as well as with overall physiological dysregulation and allostatic load. These associations were moderated by eating lifestyle and psychosocial stress.

DOI

看護実習におけるインシデントチェックリストの作成過程と試用

今野美紀, 門間正子, 松原三智子, 澤田いずみ, 杉山厚子, 堀口雅美, 安川揚子, 中井夏子, 波川京子, 田野英里香, 奥宮暁子

札幌医科大学保健医療学部紀要 = Bulletin of School of Health Sciences Sapporo Medical University ( 札幌医科大学保健医療学部 ) ( 13 ) 59 - 64 2011年03月

札幌医科大学保健医療学部看護学科実習検討会では、看護学生が係わった実習中のインシデントを教育に活かすために、簡便なインシデントチェックリストを平成20年度に作成し、平成21年度に試用した。インシデントの定義を明確にし、インシデントが発生した場合の学生、教員、実習検討会の対応を決め、学生と教員に周知を図った。平成21年度に実習した2?4年生は159名で、提出されたチェックリストは総計18件、インシデントの種類では「個人情報の取り扱い不備」が7件と最多であった。インシデントの要因として「学生側の問題」では、「予想外の行動を引き起こすリスクへの認識の甘さ」14件、「指導者側の問題」では、「指導者としての役割認識の不足」および「学生に対するアセスメント不足」が各7件であった。再発防止という点から記述があった15件のうち、具体的記述があったのは4件であった。今後、チェックリストを改良した上でデータを蓄積し、データに基づく教育活動を実践していく予定である。

DOI CiNii

慢性ストレスに関連する心理社会要因と若年健常男子の血管健康度を媒介するアロスタティック負荷

田中豪一, 堀口雅美, 小笠原晴子, 松村健太, 岡村尚昌, 矢島潤平, 津田彰

日本補完代替医療学会学術集会プログラム・抄録集 ( 日本補完代替医療学会 ) 11回 72 - 72 2008年11月

心血管系の新しい簡易健康評価法としての指動脈弾性特性分析:―青年における性差および脈波速度との相関関係―

堀口雅美, 田中豪一, 松村健太, 岡安多香子

健康心理学研究 ( The Japanese Association of Health Psychology ) 19 ( 1 ) 37 - 47 2006年 [査読有り]

Finger arterial elasticity and brachial-ankle pulse wave velocity [baPWV]were measured in 51 healthy young participants (30 men and 21 women) and the correlation between these measures was examined. Finger arterial elasticity can be evaluated by using an exponential model of the pressure-volume relationship of three model parameters a, b, and n [V=a-b×exp (-nP) ]. These parameters were estimated for three ranges of transmural pressure: overall, under 40mmHg, and over 30mmHg, using a finger occlusion maneuver. On the overall and the over 30mmHg of transmural pressure, parameter n in women was larger than those in men. It is probable that differences in finger arterial size caused the larger parameter aobserved in men, compared to women. In men, the correlation of overall (-0.395), and over 30mmHg (-0.406) conditions between parameter n and baPWV were significant. It is concluded that the exponential model of pressure-volume relationship was demonstrated to be useful for the assessment of finger arterial stiffness. Moreover, the elasticity of the finger artery seemed to be greater in healthy young women than in men.

DOI CiNii

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