Misc - 畠中　正光

Magnetization transfer contrast(MTC)に及ぼす筋収縮の影響について

畠中 正光, 大塚 誠, 石神 康生

日本医学放射線学会雑誌 ( (公社)日本医学放射線学会 )  59 ( 2 ) S56 - S57  1999年02月

Acute suppurative perithyroiditis: MR findings

M Hatakenaka, J Murakami, S Murayama, S Sakai, N Hashiguchi, Y Zaizen, S Suita, K Sakamoto, K Kusuhara, K Masuda

PEDIATRIC RADIOLOGY ( SPRINGER VERLAG )  27 ( 4 ) 353 - 355  1997年04月

　概要を見る

We report the MR findings in two cases of acute suppurative perithyroiditis. MR has the advantages over other imaging modalities of being able to distinguish areas of inflammation from adjacent normal tissue and of allowing imaging in planes which more accurately demonstrate the extent of the lesion. MR imaging is one of the most useful methods to evaluate this entity.

DOI PubMed

Acute suppurative perithyroiditis: MR findings

M Hatakenaka, J Murakami, S Murayama, S Sakai, N Hashiguchi, Y Zaizen, S Suita, K Sakamoto, K Kusuhara, K Masuda

PEDIATRIC RADIOLOGY ( SPRINGER VERLAG )  27 ( 4 ) 353 - 355  1997年04月

　概要を見る

We report the MR findings in two cases of acute suppurative perithyroiditis. MR has the advantages over other imaging modalities of being able to distinguish areas of inflammation from adjacent normal tissue and of allowing imaging in planes which more accurately demonstrate the extent of the lesion. MR imaging is one of the most useful methods to evaluate this entity.

DOI

The Ca2+-activation profile of rabbit fast skeletal myofibrils is not affected by troponin T isoforms

M Hatakenaka

BIOMEDICAL RESEARCH-TOKYO ( BIOMED RES FOUND )  17 ( 1 ) 95 - 100  1996年02月

　概要を見る

In order to clarify the role of troponin T isoforms in the Ca2+-regulation of fast skeletal muscle contraction, two myofibrillar preparations were prepared from rabbit fast skeletal myofibrils, by the use of a novel procedure for exchanging troponin T isoforms in myofibrils; more than 80% of troponin T isoforms consisted of troponin T-1f in one myofibrillar preparation, while almost all of the troponin T consisted of troponin T-2f in the other preparation. These two myofibrillar preparations showed exactly the same activation profiles of Ca2+-sensitive Mg-ATPase activity. This indicates that troponin T isoforms do not affect the Ca2+-activation profiles of rabbit fast skeletal muscle contraction under physiological conditions.

DOI

The Ca2+-activation profile of rabbit fast skeletal myofibrils is not affected by troponin T isoforms

Masamitsu Hatakenaka

Biomedical Research ( Biomedical Research Foundation )  17 ( 1 ) 95 - 100  1996年

　概要を見る

In order to clarify the role of troponin T isoforms in the Ca2+-regulation of fast skeletal muscle contraction, two myofibrillar preparations were prepared from rabbit fast skeletal myofibrils, by the use of a novel procedure for exchanging troponin T isoforms in myofibrils more than 80% of troponin T isoforms consisted of troponin T1f in one myofibrillar preparation, while almost all of the troponin T consisted of troponin T2f in the other preparation. These two myofibrillar preparations showed exactly the same activation profiles of Ca2+-sensitive Mg-ATPase activity. This indicates that troponin T isoforms do not affect the Ca2+-activation profiles of rabbit fast skeletal muscle contraction under physiological conditions.

DOI

EFFECT OF REMOVAL AND RECONSTITUTION OF TROPONIN-C AND TROPONIN-I ON THE CA2+-ACTIVATED TENSION DEVELOPMENT OF SINGLE GLYCERINATED RABBIT SKELETAL-MUSCLE FIBERS

M HATAKENAKA, OHTSUKI, I

EUROPEAN JOURNAL OF BIOCHEMISTRY ( SPRINGER VERLAG )  205 ( 3 ) 985 - 993  1992年05月

　概要を見る

The effect of troponin T treatment on the Ca2+-activated tension of single glycerinated rabbit skeletal muscle fibers was examined. The tension of the fiber was completely desensitized to Ca2+ by incubation in a solution containing an excessive amount of troponin T and reached a level of about 70% of the maximum tension of the control fiber. SDS/PAGE showed that most of troponins C and I was removed from the fiber by troponin T treatment. During the course of troponin T treatment, the cooperativity of Ca2+ activation (Hill coefficient) was decreased while pCa at half-maximal Ca2+-sensitive tension (pK) increased. Using the 26-K fragment of troponin T, the study indicated that the removal of troponins C and I was due to the replacement of the troponin C . I . T complex in the myofibrils of the fiber with the added troponin T. The troponin-T-treated fiber was again sensitized to Ca2+ by the addition of troponin C . I. The removal of troponin C by treatment with trans-1,2-cyclohexanediamine-N,N,N',N'-tetraacetic acid did not change the minimum tension of the fiber, from which troponin C . I was partially removed by troponin T treatment, but it decreased the height of maximum tension with a concomitant decrease in the Hill coefficient as well as a decrease in pK. The above findings suggested that pK is determined by the balance between two opposite actions through troponins C and I, while the extent of cooperativity of Ca2+ activation seemed to be related mainly to the content of troponin C.

DOI PubMed CiNii

REPLACEMENT OF 3 TROPONIN COMPONENTS WITH CARDIAC TROPONIN COMPONENTS WITHIN SINGLE GLYCERINATED SKELETAL-MUSCLE FIBERS

M HATAKENAKA, OHTSUKI, I

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ( ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS )  181 ( 3 ) 1022 - 1027  1991年12月

DOI PubMed CiNii