Details of a Researcher

Papers - Tomoko UNO

Division display >> ／ All the affair displays 1 - 44 of about 44

A diet supplemented with cholic acid elevates blood pressure accompanied by albuminuria in rats

Tomoko Shimoda, Hidehisa Shimizu, Wakana Iwasaki, Hongxia Liu, Yoshie Kamo, Koji Tada, Taketo Hanai, Shota Hori, Ga-Hyun Joe, Yasutake Tanaka, Masao Sato, Hitoshi Miyazaki, Satoshi Ishizuka

Bioscience, Biotechnology, and Biochemistry ( Oxford University Press (OUP) ) 2023.01

Abstract A diet supplemented with cholic acid (CA), the primary 12α-hydroxylated bile acid, can induce hepatic lipid accumulation in rats without obesity. This study examined the effects of a CA-supplemented diet on blood pressure (BP). After acclimation, WKAH/HkmSlc rats (3 week old) were divided into two groups and fed with a control AIN-93-based diet or a CA-supplemented diet (0.5 g CA/kg) for 13 weeks. The CA diet increased systolic and diastolic BP as well as hepatic lipid concentrations in the rats. No changes were found in the blood sodium concentration. Urinary albumin concentration increased in CA-fed rats. An increase was observed in the hepatic expression of ATP binding cassette subfamily B member 1B that correlated BPs and urinary albumin concentration accompanied by an increase in portal taurocholic acid concentration. These results suggest that 12α-hydroxylated bile acids are involved in increased BP and albuminuria via alteration of hepatic function.

DOI

Cognitive changes with psychomotor skill acquisition through blended learning among nursing students: A qualitative study.

Yuko Yoshida, Tomoko Uno, Hiroaki Tanaka, Itsuka Hakosaki, Katsusuke Shigeta, Rika Yano

Nurse education in practice 65 103486 - 103486 2022.11 [International journal]

AIM: This study described nursing students' cognitive changes as they acquire psychomotor skills through blended learning. BACKGROUND: Deliberate practice, including feedback from teachers, is vital for acquiring psychomotor skills. Blended learning, a program that allows students to deepen their learning and improve their skills even when students and faculty are physically separated has attracted significant attention in recent years. Although blended learning has been used for learning in the cognitive domain, no study has examined its effectiveness in the acquisition of psychomotor skills. Understanding how students' cognition changes as they acquire skills in a blended learning environment could be a valuable resource for effective teaching. DESIGN: An inductive, qualitative description approach was adopted. METHODS: The program involved a basic nursing skill: making an occupied bed. Eleven second-year nursing students participated. The participants attended face-to-face lectures and e-learning courses comprising self-study content that was designed for easy and frequent reference. Students practiced for a skill test, which was conducted one month after the first lecture. Two interviews were conducted approximately one month apart. Before each interview, the participants' current practices were videotaped. During the interviews, they explained their thought processes and conscious awareness of their actions as they watched the videos. This study was conducted between April and May 2019. RESULTS: Six categories related to changes in participants' cognitive processes while acquiring the skill of making an occupied bed were identified: "feeling that it is easy to acquire," "practicing without much thought," "realizing the difficulty in translating thoughts into practice," "experiencing a sense of purpose in each technique," "gaining a perspective to evaluate one's skills," and "developing one's unique approach." CONCLUSIONS: In a blended learning environment, where a practice environment and audiovisual materials were provided, students could practice and improve their skills at their own pace even without the instructor's frequent advice. The findings show that metacognitive skills are essential to the development of psychomotor skills in a blended learning program because this program requires practicing while monitoring one's skills. Metacognitive skills affect the development of psychomotor skills and the ability to provide care. Therefore, initiatives that address the development of metacognitive skills, such as the current program, during the early stages of basic education programs can contribute to the development of nursing students' practical skills.

DOI PubMed

COVID-19感染拡大により学内実習に変更した基礎看護実習2に関する教育実践報告

宇野智子, 中村円, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 87 - 91 2022.03 [Refereed]

COVID-19感染拡大により学内実習に変更した基礎看護実習1に関する教育実践報告

飯澤良祐, 宇野智子, 中村円, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 93 - 97 2022.03 [Refereed]

COVID-19感染拡大により遠隔代理実践を導入した看護技術総合演習に関する教育実践報告

中村円, 宇野智子, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 99 - 103 2022.03 [Refereed]

COVID-19感染拡大により遠隔代理実践を導入した看護技術総合演習に関する教育実践報告

中村円, 宇野智子, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 99 - 103 2022.03 [Refereed]

学生の看護実践能力を育成するためには看護実践の基礎である看護過程の理解が不可欠である.本報告はCOVID-19感染拡大により遠隔授業に変更した演習科目「看護技術総合演習」の実践過程からその学習効果と今後の課題について報告し,ICTを活用した看護技術教育の授業設計を行う上での基礎資料とすることを目的とした.遠隔授業での演習には,学生が立案した看護計画を教員が代理で実践する「遠隔代理実践」を導入し,学生が間接的に看護実践を体験できるようにした.遠隔代理実践を通して,学生は計画を立案するだけでなく,患者へのケアを行う際に看護師がどのような思考で状況を判断して観察を行い,一つ一つの看護行為を省察しながら次の看護行為を決定しているということを学んでいた.遠隔代理実践を用いることは学生の臨床判断能力の醸成と,患者の反応や状況に応じて計画を修正しながら実践するという看護のプロセスを理解することにつながっていた.(著者抄録)

COVID-19感染拡大により学内実習に変更した基礎看護実習2に関する教育実践報告

宇野智子, 中村円, 飯澤良祐, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 87 - 91 2022.03 [Refereed]

本報告は新型コロナウイルス感染症の拡大前後の実践過程を通して,臨地実習を学内実習へ変更したことにより,看護実践能力を育成する上で基礎看護学領域が担う課題を明らかにすることを目的とした.学内実習は,感染対策を講じた上で対面での模擬実践と自宅からの遠隔での学内実習(模擬患者の看護過程)を組み合わせた.このような教育方法によって看護過程の思考を学ぶことが可能だと考えた.一方,直接的な患者とのコミュニケーションや援助関係の構築,学生指導看護師への報告や相談といった対人的な経験および看護過程の実施と評価の学習は限界があった.患者に看護を提供するには,健康状態の変化に対応した思考力や判断力,対人関係能力といった看護実践能力を高めることが重要である.今後,基礎看護学領域が担うべき課題は,学生が知識や技術および態度を主体的にその後の講義や臨地実習の学習と統合させ,看護実践能力の基盤を育成することである.(著者抄録)

COVID-19感染拡大により学内実習に変更した基礎看護実習1に関する教育実践報告

飯澤良祐, 宇野智子, 中村円, 首藤英里香, 堀口雅美, 大日向輝美

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) ( 11 ) 93 - 97 2022.03 [Refereed]

本報告はCOVID-19感染拡大により学内実習に変更した基礎看護実習1の教育実践を振り返り,基礎看護学における看護実践能力の育成につなげるための学内実習の有効であった点と課題を明確にすることを目的とした.学内実習では看護の役割や連携に関する講義,病院と病棟ならびに看護活動に関する動画の視聴,看護師へのインタビューを実施した.学習内容の順序性を考慮し,関連付けて学習できるようにした.学生は臨床の場での看護活動や対象者との関わりを知り,対象者やチーム医療に必要な対人関係能力,倫理観について学ぶことができたと考える.学内実習により対象者との援助関係の構築や学生指導看護師と関わりチームの一員として役割を果たすことは実際の体験を通して学ぶことはできず,この点は2年次以降の学習で補う必要がある.基礎看護学において看護実践能力の基盤を形成し,看護に対する洞察を深めていけるよう教育活動を行う必要がある.(著者抄録)

Nutritional Evaluation by Nurses and Physical Recovery of Malnourished Patients after Esophagectomy

Tomoko Uno, Sadako Yoshimura

Open Journal of Nursing ( Scientific Research Publishing, Inc. ) 12 ( 01 ) 12 - 24 2022 [Refereed]

DOI

Association between Physical Activity Levels and Body Composition among Healthy Older Japanese Adults during a Snowy Winter: A Cross-Sectional Study.

Tomoko Shimoda, Teppei Suzuki, Kaori Tsutsumi, Mina Samukawa, Sadako Yoshimura, Katsuhiko Ogasawara

International journal of environmental research and public health 17 ( 15 ) 2020.07 [International journal]

BACKGROUND: Despite a long average lifespan, increased life expectancy does not guarantee higher quality of life. METHODS: To contribute in understanding some determinants of healthy life expectancies in older Japanese individuals in a snowy winter region, we investigated the indicators of health. Local residents (n = 124) in the city of Iwamizawa volunteered for health examinations from January 2016 to March 2016. We recorded activity via daily steps for 2-week periods. In addition, we measured body composition, grip strength, and assessed nutritional status. RESULTS: Analysis of body composition and daily activity indicated that women who walked more than 4000 steps had lower fat mass and increased muscle mass. Men with >3.0 metabolic equivalents (METs) when walking had lower body fat. CONCLUSION: For healthy older Japanese individuals in this snowy winter region, walking >4000 steps daily for women and exercise of >3.0 METs for men may indicate health-promoting activities.

DOI PubMed

A low coefficient of variation in hepatic triglyceride concentration in an inbred rat strain.

Tomoko Shimoda, Shota Hori, Kenta Maegawa, Akari Takeuchi, Yeonmi Lee, Ga-Hyun Joe, Yasutake Tanaka, Hidehisa Shimizu, Satoshi Ishizuka

Lipids in health and disease 19 ( 1 ) 137 - 137 2020.06 [Refereed] [International journal]

BACKGROUND: Inbred strains are characterized by less genetic variation, which suggests usefulness of inbred strains for evaluations of various parameters. In this study, experimental reproducibility in several parameters was compared between an outbred Wistar rat and Wistar King A Hokkaido (WKAH/HkmSlc) rat, the inbred strain that is originated from Wistar rats. METHODS: Difference of variations was investigated in parameters of body compositions and liver functions such as body weight, liver weight, liver triglycerides (TG), liver cholesterol and plasma alanine aminotransferase activity (ALT) between WKAH rats and outbred Wistar rats by using the coefficient of variation (CV). RESULTS: There was no difference in the CVs of body weight and relative liver weight between WKAH and Wistar rats. The CVs of body weight and relative liver weight were below 10% in both WKAH and Wistar rats. The CVs of TG, cholesterol, and ALT in Wistar rats were between 30 and 40%, whereas those in WKAH rats were between 10 and 25%. A low CV level of TG was observed in WKAH rats compared to that in Wistar rats regardless of the duration of the experimental period in those rat strains. CONCLUSION: The low CV values in metabolic parameters involved in liver functions in the inbred rats suggested an advantage of using inbred rather than outbred rats for the evaluation of liver lipid metabolism.

DOI PubMed

Examining Modifications of the Noise Generated by Nurses’ Footsteps and the Use of Pass-By Objects: A Pilot Study

Tomoko Shimoda, Rei Nishijima, Sadako Yoshimura

Open Journal of Nursing ( Scientific Research Publishing, Inc. ) 10 ( 02 ) 184 - 193 2020 [Refereed]

DOI

A simple and short microbiology practical improves undergraduate nursing students' awareness of bacterial traits and ability to avoid spreading infections.

Rika Yano, Torahiko Okubo, Tomoko Shimoda, Junji Matsuo, Hiroyuki Yamaguchi

BMC medical education 19 ( 1 ) 53 - 53 2019.02 [Refereed] [International journal]

BACKGROUND: Nurses are responsible for implementing appropriate measures to reduce hospital infections, especially with multidrug resistant bacteria, so nursing students should learn about microbiology. This helps them to understand bacterial dissemination and infectious disease control. Because of tight schedules, however, its teaching is limited in undergraduate nursing classes in Japan. We therefore tested whether a simple short practical session in a microbiology class could help to improve undergraduate nursing students' awareness of bacterial traits and how to prevent infections. METHODS: This study involved second-grade nursing students (n = 76). Two short practical sessions (a total of 3 h, across 2 days) were used to assess the effectiveness of washing or disinfection on hand bacteria in a 16-class microbiology course (total class time was 24 h, plus an exam). Hand bacteria were sampled on LB agar plates with orientation during the first half-day, and the plates examined for colonies with distinct color or morphological traits, and discussed, in the second session, a week later. Questionnaires before and after the exercise were used to assess changes in awareness of unseen bacteria inhabiting around us connecting bacterial traits and how to prevent infections. RESULTS: The results showed that the practical increased the nursing students' awareness of fomites (utensils) (p = 0.0115), fomites (contact-based) (p = 0.0016), habitats (body surface) (p = 0.0127), action facilitating hospital infection (p = 0.0166), and changes in physical condition caused by bacterial infections (p = 0.0136). There were no changes in word associations (p = 0.627) or habitats (inside body) (p = 0.308). Difficulty score, which is an element in questionnaire psychometric properties, tended to be close to the expected score through the practical, but not statistical significant. In addition, regardless of before or after practical, Cronbach α score, which is an indicator of the reliability among items of multi-choice questions, showed > 0.8, indicating validity of evaluation items. Thus, the student's awareness of unseen bacteria inhabiting around us was significantly increased as compared to those before practical in microbiology class. CONCLUSIONS: The simple short practical effectively improved nursing students' awareness of unseen bacteria inhabiting around us in microbiology course, useful for even tight teaching schedules.

DOI PubMed

Survey on the willingness to pay for tele-health consultation.

Suzuki T, Abe T, Tsuji S, Shimoda T, Yoshimura S, Ogasawara K

Health Policy and Technology. 8 248 - 253 2019 [Refereed]

Effect of thermal control of dry fomites on regulating the survival of human pathogenic bacteria responsible for nosocomial infections.

Tomoko Shimoda, Torahiko Okubo, Yoshiki Enoeda, Rika Yano, Shinji Nakamura, Jeewan Thapa, Hiroyuki Yamaguchi

PloS one 14 ( 12 ) e0226952 2019 [Refereed] [International journal]

We monitored the survival of human pathogenic bacteria [Escherichia coli (ATCC), extended-spectrum β-lactamase-producing E. coli (Clinical isolate), New Delhi metallo-β-lactamase-producing E. coli (clinical isolate), Staphylococcus aureus (ATCC)] on dry materials (vinyl chloride, aluminum, plastic, stainless steel) at distinct temperatures (room temperature or 15°C-37°C). These bacteria favored a lower temperature for their prolonged survival on the dry fomites, regardless of the material type. Interestingly, when mixed with S. aureus, E. coli survived for a longer time at a lower temperature. Cardiolipin, which can promote the survival of S. aureus in harsh environments, had no effect on maintaining the survival of E. coli. Although the trends remained unchanged, adjusting the humidity from 40% to 60% affected the survival of bacteria on dry surfaces. Scanning electron microscopic analysis revealed no morphological differences in these bacteria immediately before or after one day of dry conditions. In addition, ATP assessment, a method used to visualize high-touch surfaces in hospitals, was not effective at monitoring bacterial dynamics. A specialized handrail device fitted with a heater, which was maintained at normal human body core temperature, successfully prohibited the prolonged survival of bacteria [Enterococcus faecalis (ATCC), E. coli (ATCC), Pseudomonas aeruginosa (ATCC), S. aureus (ATCC), Acinetobacter baumannii (clinical isolate), and Serratia marcescens (clinical isolate)], with the exception of spore-forming Bacillus subtilis (from our laboratory collection) and the yeast-like fungus Candida albicans (from our laboratory collection)] on dry surfaces. Taken together, we concluded that the tested bacteria favor lower temperatures for their survival in dry environments. Therefore, the thermal control of dry fomites has the potential to control bacterial survival on high-touch surfaces in hospitals.

DOI PubMed

Factors Affecting Bone Mineral Density Among Snowy Region Residents in Japan: Analysis Using Multiple Linear Regression and Bayesian Network Model.

Teppei Suzuki, Tomoko Shimoda, Noriko Takahashi, Kaori Tsutsumi, Mina Samukawa, Sadako Yoshimura, Katsuhiko Ogasawara

Interactive journal of medical research ( Journal of Medical Internet Research ) 7 ( 1 ) e10 2018.05 [Refereed] [International journal]

BACKGROUND: As the onset of osteoporosis leads to reduced activities of daily living and may result in patients being bedridden, efforts to prevent decreased bone density are necessary. Various studies on the relationship between sex, age, nutrients, and exercise habits and bone mineral density have been conducted to date. However, for snowy region residents, the magnitude of influence of various factors affecting bone mineral density and the influence level have not been clarified. OBJECTIVE: This study aimed to clarify the degree of influence and factors influencing bone mineral density based on survey results on health conditions and lifestyle habits in heavy snow areas. METHODS: A total of 354 citizens who visited a drugstore in the target area were included in a study that included using the brief-type self-administered diet history questionnaire on lifestyle and exercise habits. Height, weight, body composition, and bone densitometer values were analyzed using multiple regression to calculate their association with bone mineral density. In addition, a Bayesian network model was used to determine the influence level of each factor as a conditional probability. RESULTS: Multiple regression analysis revealed that age, sex, fracture, and calcium intake significantly influenced bone mineral density. In addition, the result of Bayesian network analysis suggested that age and sex affected bone mineral density, whereas nutrients and exercise habits might not have a direct impact. However, calcium intake and the T-score were significant factors affecting the presence or absence of fracture experiences, suggesting that adequate calcium intake is essential for preventing fractures. CONCLUSIONS: In the multiple regression analysis, age, sex, fracture, and calcium intake were selected as factors; however, in the Bayesian analysis, only age and sex affected bone mineral density while nutrients did not. In addition, the fact that calcium intake and the T-score were shown to affect bone fracture history suggests that calcium intake is an important measure that can prevent bone fractures. Overall, these results suggest that measures such as ensuring a bone fracture-free environment and providing nutritional advice for calcium intake can be effective in preventing bone loss.

DOI PubMed

医療施設で発生する音の快・不快評価音源の確信は音の感じ方に影響するか?

歳桃晴子, 太田瑞菜, 下田智子, 進藤ゆかり

北海道公衆衛生学雑誌 ( 北海道公衆衛生学会 ) 31 ( 2 ) 77‐84 - 84 2018.03

医療施設で発生する音に対する快・不快の評価と、その音が何であるかを確信している程度(音確信度)がどのように関係しているか、およびこの音確信度に影響する要因について明らかにし、今後の医療施設等での音環境への配慮に対して示唆を得ることを研究目的とした。対象者は20歳以上の学生23名で、疑似病室内で20種類の音を再生し、各音に対する快・不快評価、その音が何だと思うか、音確信度、音を聞いた経験の有無について調査した。その結果、音確信度が高い方が快い傾向にある音と、音確信度が高い方が不快な傾向にある音があった。音を聞いた経験があることは音確信度を向上させ、音の種類について事前にまとめて説明することは音確信度を高めず、むしろ低下させる場合があった。音の正答率と音確信度には有意に正の相関があった。以上のことより、医療施設で発生する音の種類によって、配慮方法を使い分けることが重要と示唆された。(著者抄録)

J-GLOBAL

高齢女性における尿失禁と立ち上がり機能の関係性について

寒川美奈, 鈴木哲平, 下田智子, 堤香織, 高橋紀子, 高島理沙, 辻真太朗, 村田和香, 良村貞子, 小笠原克彦

日本未病システム学会学術総会抄録集 ( (一社)日本未病学会 ) 24回 134 - 134 2017.10

Diversity changes of microbial communities into hospital surface environments.

Rika Yano, Tomoko Shimoda, Reina Watanabe, Yasutoshi Kuroki, Torahiko Okubo, Shinji Nakamura, Junji Matsuo, Sadako Yoshimura, Hiroyuki Yamaguchi

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy ( ELSEVIER SCIENCE BV ) 23 ( 7 ) 439 - 445 2017.07 [Refereed] [International journal]

Previous works have demonstrated considerable variability in hospital cleanliness in Japan, suggesting that contamination is driven by factors that are currently poorly controlled. We undertook 16S rRNA sequence analysis to study population structures of hospital environmental microbiomes to see which factor(s) impacted contamination. One hundred forty-four samples were collected from surfaces of three hospitals with distinct sizes ("A": >500 beds, "B": 100-500 beds, "C": <100 beds). Sample locations of two ward types (Surgical and Internal) included patient room bed table (multiple) (4BT), patient overbed table (multiple) (4OT), patient room sink (multiple) (4S), patient room bed table (single) (SBT), patient overbed table (single) (SOT), patient room sink (single) (SS), nurse desk (ND), and nurse wagon (NW). Total DNA was extracted from each sample, and the 50 samples that yielded sufficient DNA were used for further 16S rRNA sequencing of hospital microbiome populations with cluster analysis. The number of assigned bacterial OTU populations was significantly decreased in hospital "C" compared to the other hospitals. Cluster analysis of sampling locations revealed that the population structure in almost all locations of hospital "C" and some locations in the other hospitals was very similar and unusually skewed with a family, Enterobacteriaceae. Interestingly, locations included patient area (4OT, 4BT, SBT) and nurse area (ND), with a device (NW) bridging the two and a place (4S and SS) shared between patients or visitors. We demonstrated diversity changes of hospital environmental microbiomes with a skewed population, presumably by medical staff pushing NWs or sinks shared by patients or visitors.

DOI PubMed

Nutritional Status and Body Composition of Independently Living Older Adults in a Snowy Region of Japan.

Shimoda T, Suzuki T, Takahashi N, Tsutsumi K, Samukawa M, Yoshimachi S, Goto T, Enomoto H, Kise N, Ogasawara K, Yoshimura S

Gerontology & geriatric medicine ( SAGE PUBLICATIONS INC ) 3 2333721417706854 2017.01 [Refereed]

Lifestyle diseases, which are associated with nutrition, account for 30% of elderly requiring long-term care. To increase health expectancy among Japan's rapidly aging population, we investigated the nutritional status and body composition of elderly adults living in a region subject to heavy snowfall, to identify pertinent health indicators. The dietary habits of 288 local residents aged >= 50 years were analyzed using body composition and a brief-type self-administered diet history questionnaire. Body mass index of all residents was normal. Basal metabolic rate (BMR) and muscle mass were reduced in the older group. Dietary habits did not differ with age among men, but older women had significantly higher dietary intake. BMR and muscle mass declined with age, even when dietary intake was sustained. Despite sufficient dietary intake, independently living older adults demonstrate less efficient use of food with age. Interventions to reduce excessive sodium and protein intake are required.

DOI PubMed

冬期における豪雪地域住民の年代別体組成および骨密度の実態高齢者の筋肉量と骨密度に着目して

下田智子, 鈴木哲平, 堤香織, 高橋紀子, 寒川美奈, 後藤輝明, 吉町昌子, 小笠原克彦, 良村貞子

日本未病システム学会学術総会抄録集 ( (一社)日本未病学会 ) 23回 125 - 125 2016.10

The influence of sound awareness on the level of sound generated during nursing activity in a pseudo-ward.

Shimoda T, Asai M, Yoshida R, Aoki R, Yano R

Open Journal of Nursing. 6 ( 4 ) 267 - 273 2016 [Refereed]

ATP bioluminescence values are significantly different depending upon material surface properties of the sampling location in hospitals.

Tomoko Shimoda, Rika Yano, Shinji Nakamura, Mitsutaka Yoshida, Junji Matsuo, Sadako Yoshimura, Hiroyuki Yamaguchi

BMC research notes 8 807 - 807 2015.12 [Refereed] [International journal]

BACKGROUND: Our previous study into assessing hospital cleanliness in Japan by two common methods, ATP bioluminescence and the stamp agar method, revealed considerable variability in the data of both methods (BMC Research Notes, 7: 121, 2014). To investigate the reason(s) for the variability, we reanalyzed the data (n = 752) from the point of view of the material surface properties of sampling sites. METHODS: Data obtained from surfaces with unknown properties and different purposes such as floor were omitted, and the remaining data (n = 488) were used for this study. The material surface properties on sampling sites were divided into six categories: melamine coated (n = 216), vinyl chloride (n = 16), stainless steel (n = 144), wood (n = 63), and acrylonitrile-butadiene styrene resin coated (n = 48). The data between individual material properties were compared. RESULTS: The ATP values of high-touch places were significantly different depending on the type of surface, but no significant difference in stamp values between material properties was seen, indicating that in contrast to stamp values, ATP-accumulation more depends on the physical properties of the material surface such as electronic charges or roughness. To confirm this, we assessed a degree of roughness on vinyl chloride material surface (disutilized floor samples actually used for each of the hospitals) by observation with scanning electron microscope (SEM). As a result, SEM observation similarly revealed considerable roughness on the materials, which may allow microbes to contaminate the materials without noticing it. CONCLUSION: Material properties must be considered when evaluating hospital cleanliness with ATP values, and provide a strong warning into evaluating hospital cleanliness.

DOI PubMed

A characteristic of polymorphic membrane protein F of Chlamydia trachomatis isolated from male urogenital tracts in Japan

Tomohiro Yamazaki, Junji Matsuo, Satoshi Takahashi, Shouta Kumagai, Tomoko Shimoda, Kiyotaka Abe, Kunihiro Minami, Hiroyuki Yamaguchi

Journal of Infection and Chemotherapy ( Elsevier ) 21 ( 12 ) 842 - 848 2015.12 [Refereed]

Although sexually transmitted disease due to Chlamydia trachomatis occurs similarly in both men and women, the female urogenital tract differs from that of males anatomically and physiologically, possibly leading to specific polymorphisms of the bacterial surface molecules. In the present study, we therefore characterized polymorphic features in a high-definition phylogenetic marker, polymorphic outer membrane protein (Pmp) F of C. trachomatis strains isolated from male urogenital tracts in Japan (Category: Japan-males, n = 12), when compared with those isolated from female cervical ducts in Japan (Category: Japan-females, n = 11), female cervical ducts in the other country (Category: Ref-females, n = 12) or homosexual male rectums in the other country (Category: Ref-males, n = 7), by general bioinformatics analysis tool with MAFFT software. As a result, phylogenetic reconstruction of the PmpF amino acid sequences showing three distinct clusters revealed that the Japan-males were limited into cluster 1 and 2, although there were only four clusters even though including an outgroup. Meanwhile, the phylogenetic distance values of PmpF passenger domain without hinge region, but not its full-length sequence, showed that the Japan-males were more stable and displayed less diversity when compared with the other categories, supported by the sequence conservation features. Thus, PmpF passenger domain is a useful phylogenetic maker, and the phylogenic features indicate that C. trachomatis strains isolated from male urogenital tracts in Japan may be unique, suggesting an adaptation depending on selective pressure, such as the presence or absence of microbial flora, furthermore possibly connecting to sexual differentiation.

DOI PubMed

特別豪雪地帯に住む高齢者の積雪時および非積雪時の活動量と体組成の実態調査

下田智子, 寒川美奈, 小笠原克彦, 良村貞子

日本未病システム学会学術総会抄録集 ( (一社)日本未病学会 ) 22回 131 - 131 2015.09

病床規模の異なる病院におけるATP(アデノシン三リン酸)値を用いた環境表面清浄度調査

渡辺玲奈, 下田智子, 矢野理香, 良村貞子

看護総合科学研究会誌 ( 看護総合科学研究会 ) 16 ( 1 ) 13 - 21 2015.05

本研究は,病床規模の異なる3病院において,清浄度に影響すると予測される診療科と平均在院日数,患者および看護師の管理環境に焦点をあて,ATP値を用い高頻度に接触する環境表面別清浄度の実態を明らかにすることを目的とした。調査対象は,病床規模の違う3病院(500床以上:A病院,100床以上500床未満:B病院,100床未満:C病院,各1病院)における8病棟内の高頻度接触表面とした。調査方法は,各病棟の高頻度接触表面のうち看護師管理環境3ヶ所,患者管理環境6ヶ所の計9ヶ所からサンプルを採取し,各ATP値を看護師管理環境群と患者管理環境群,診療科間で比較検討した。その結果,全測定場所における病院毎のATP中央値は全て500RLU未満であり,清浄度は保たれていた。また,全ての病院で看護師管理環境が患者管理環境よりも有意にATP値が低かった。さらに,C病院では看護師管理環境と患者管理環境の両方において,診療科間での差が見られた。よって,患者管理環境において,清浄度を保つためには,清掃の質等,清浄度に影響する要因を明らかにする必要性が示唆された。(著者抄録)

J-GLOBAL

Development and current status of an advanced telehealth consultation system in Japan

Tomoko Shimoda, Sadako Yoshimura, Yuko Yoshida, Mitsuhiro Okazaki, Teruaki Gotou, Shingo Tamura, Katsuhiko Ogasawara

JOURNAL OF TELEMEDICINE AND TELECARE ( SAGE PUBLICATIONS LTD ) 21 ( 3 ) 176 - 178 2015.04 [Refereed]

DOI PubMed

A Study of Nurse Standing Position at the Bedside Considering the Patient's Personal Space

FUTAMI ASAKO, KUDO YUKI, NOMOTO TATSUYA, SHIMODA TOMOKO, YOSHIMURA SADAKO

日本看護技術学会誌 ( (一社)日本看護技術学会 ) 13 ( 3 ) 211 - 218 2014.12

【目的】他患がいる病室において、患者が話しやすいと思う看護者の立ち位置を明らかにする。【方法】擬似病室で、模擬患者に話しやすいと思う位置の回答を求める準実験研究を行った。パーソナルスペース(以下PS)は被験者の頭頂から半径120cm以内とした。【結果】話しやすい距離の平均は134.7±26.9cmであった。また、PSの120cm以内が話しやすいと答えたのは30.4%であり、120〜130cmと答えたのは26.1%であった。さらに、看護師役の立ち位置を被験者の頭頂から45°±10°の範囲と答えた被験者は65.2%であった。【結論】1. 話しやすい立ち位置は、被験者の頭から120〜130cm程度離れたベッドに近い足元側が目安である。2. 話しやすい立ち位置は、45°±10°の範囲内に約7割が集中した。3. 会話を重ねると、話しやすい位置は近くなる可能性がある。4. 看護師側が考える話しやすい距離と患者側が考える話しやすい距離は異なる可能性がある。(著者抄録)

DOI CiNii J-GLOBAL

Visualization of hospital cleanliness in three Japanese hospitals with a tendency toward long-term care.

Reina Watanabe, Tomoko Shimoda, Rika Yano, Yasuhiro Hayashi, Shinji Nakamura, Junji Matsuo, Hiroyuki Yamaguchi

BMC research notes 7 121 - 121 2014.03 [Refereed] [International journal]

BACKGROUND: Hospital cleanliness in hospitals with a tendency toward long-term care in Japan remains unevaluated. We therefore visualized hospital cleanliness in Japan over a 2-month period by two distinct popular methods: ATP bioluminescence (ATP method) and the standard stamp agar method (stamp method). METHODS: The surfaces of 752 sites within nurse and patient areas in three hospitals located in a central area of Sapporo, Japan were evaluated by the ATP and stamp methods, and each surface was sampled 8 times in 2 months. These areas were located in different ward units (Internal Medicine, Surgery, and Obstetrics and Gynecology). Detection limits for the ATP and stamp methods were determined by spike experiments with a diluted bacterial solution and a wipe test on student tables not in use during winter vacation, respectively. Values were expressed as the fold change over the detection limit, and a sample with a value higher than the detection limit by either method was defined as positive. RESULTS: The detection limits were determined to be 127 relative light units (RLU) per 100 cm2 for the ATP method and 5.3 colony-forming units (CFU) per 10 cm2 for the stamp method. The positive frequency of the ATP and stamp methods was 59.8% (450/752) and 47.7% (359/752), respectively, although no significant difference in the positive frequency among the hospitals was seen. Both methods revealed the presence of a wide range of organic contamination spread via hand touching, including microbial contamination, with a preponderance on the entrance floor and in patient rooms. Interestingly, the data of both methods indicated considerable variability regardless of daily visual assessment with usual wiping, and positive surfaces were irregularly seen. Nurse areas were relatively cleaner than patient areas. Finally, there was no significant correlation between the number of patients or medical personnel in the hospital and organic or microbiological contamination. CONCLUSIONS: Ongoing daily hospital cleanliness is not sufficient in Japanese hospitals with a tendency toward long-term care.

DOI PubMed

大学と調剤薬局を結んだ遠隔健康相談 400例の相談内容と今後の展開

小笠原克彦, 下田智子, 吉田祐子, 良村貞子, 岡崎光洋, 後藤輝明, 吉町昌子, 岩丸宏明, 田村信吾, 森山広行, 黄瀬信之

医療情報学連合大会論文集 ( (一社)日本医療情報学会 ) 33回 1216 - 1217 2013.11

テキストマイニングを用いた高度遠隔健康相談内容の探索的検討

下田智子, 良村貞子, 岡崎光洋, 後藤輝明, 吉町昌子, 岩丸宏明, 田村信吾, 小笠原克彦

日本医療情報学会看護学術大会論文集 ( 日本医療情報学会看護部会 ) 14回 51 - 52 2013.07

高速インターネットによる健康相談システムを開発し、遠隔健康相談ができるようになった。この遠隔健康相談記録の内容をテキストマイニング技法により、探索的検討を行った。分析対象期間は2010年3月から2012年6月であった。利用件数は354件(男性122名、女性230名、不明2名)であった。店舗ごとの相談件数は北海道内の4店舗はほぼ同数であり、僻地型、都市近郊型、都市型で差はなかった。利用者の年齢は10から90歳代であり、70歳代が最も多かった。相談内容は、健康相談、育児、排泄、栄養、生活習慣病、運動等であった。全相談のうち16%は、医療機関への受診が必要と判断し、利用者へ受診推奨をした。相談内容を分析すると、名詞では「薬」「受診」「血圧」の出現頻度が高く、形容詞では「高い」「悪い」「痛い」が頻度の上位を占めていた。各言語間の相関関係は明らかにならなかった。「受診」の頻度が高いのは受診すべきか否かを判断して欲しい利用者のニーズの現れであると考えられた。

地域住民からの健康相談対応に期待される看護師と薬剤師の連携に関する調査研究

平塚美奈, 岡崎光洋, 小笠原克彦, 下田智子, 良村貞子, 中安一幸, 後藤輝明, 吉町昌子

日本薬学会年会要旨集 ( (公社)日本薬学会 ) 133年会 ( 4 ) 196 - 196 2013.03

Analysis of a Participant-Observer Study on Nurses' Observations (MIMAMORI) of Self-Feeding in Dysphagic Patients: the Second Report

下田智子, 八幡磨並, 山本留美加, 及川幸子, 良村貞子

看護総合科学研究会誌 ( 看護総合科学研究会 ) 14 ( 2 ) 17 - 28 2013.02

看護師が行う食事時の見守りは，患者の自立に向け，観察やモニタリング機能を担う重要な行為である。看護師は，見守りする中でフィジカルアセスメントに基づき食事に関する直接的ケアを提供しているが，このような援助内容について具体的に検討した先行研究はない。そこで，本研究では嚥下障害のある患者に対する食事時の見守りが，どのような看護技術内容で構成されているのかを明らかにすることを目的とした。Ａ病院の神経内科・外科病棟で収集したデータは10事例であった。その結果，以下の点が明らかになった。１．嚥下障害のある患者の食事時の見守りは，視診，問診，聴診，およびコミュニケーション技術を用いて，安全性を確保しながら行われていた。２．看護師は，食事の見守りの際，視診によって多くの情報を得ているが，視診による見守りは，第三者が確認しにくいことが明らかになった。３．見守りにおける視診等は，姿勢を整えるなどの直接的ケアと並行して実施されていた。

CiNii J-GLOBAL

Analysis of a Participant-Observer Study on Nurses' Observations (MIMAMORI) of Self-Feeding in Dysphagic Patients: the First Report

下田智子, 八幡磨並, 山本留美加, 及川幸子, 良村貞子

看護総合科学研究会誌 ( 看護総合科学研究会 ) 14 ( 1 ) 15 - 29 2012.06 [Refereed]

見守りは，援助者が対象者に対し，必要な介助や支援ができるような体制を整えて，意図的にその行為や様子を観察することである。また，看護師は患者の自立に向けた健康回復への支援において見守りを行うことが多いが，意図的な見守りが患者や家族に認識されていない場合もある。そこで，本研究では自立に向けたケアの一場面である嚥下障害の患者に対する食事時の見守りに着目し，その実態を参加観察法で調査した。Ａ病院の神経内科・外科病棟で収集したデータは10場面であった。その結果，以下の点が明らかになった。１．嚥下障害のある患者の食事時の看護師による見守りは，患者の状態に応じて，自立に向け，代償的な直接的ケアも合わせ行われていた。２．見守りは，患者の自立に向け，個別的アセスメントに基づき，その項目や時間が変化していた。３．「姿勢を整える」などの見守り時の看護師の直接的ケアは，姿勢の保持を観察することより他者に容易に理解可能な行為であった。

CiNii J-GLOBAL

遠隔健康相談システムを用いた薬局における健康相談の臨床実証報告

岡崎光洋, 小笠原克彦, 阿部保, 下田智子, 良村貞子, 中安一幸, 後藤輝明, 吉町昌子, 岩丸宏明, 田村信吾

日本薬学会年会要旨集 ( (公社)日本薬学会 ) 132年会 ( 4 ) 189 - 189 2012.03

遠隔健康相談サービスの支払意志額の推計

阿部保, 中安一幸, 良村貞子, 下田智子, 岡崎光洋, 田村信吾, 岩丸宏明, 後藤輝明, 吉町昌子, 小笠原克彦

医療情報学連合大会論文集 ( (一社)日本医療情報学会 ) 31回 771 - 772 2011.11

調剤薬局に設置した遠隔保健相談システム運用1年6ヵ月間の相談状況分析

小笠原克彦, 阿部保, 下田智子, 良村貞子, 中安一幸, 岡崎光洋, 後藤輝明, 吉町昌子, 岩丸宏明, 田村信吾

医療情報学連合大会論文集 ( (一社)日本医療情報学会 ) 31回 769 - 770 2011.11

調剤薬局に設置した遠隔保健相談システムの開発と実証実験

小笠原克彦, 佐瀬雄治, 吉田祐子, 岡崎光洋, 後藤輝明, 吉町昌子, 岩丸宏明, 田村信吾, 下田智子, 良村貞子

医療情報学連合大会論文集 ( (一社)日本医療情報学会 ) 30回 1181 - 1182 2010.11

Effect of Chronic Intake of Red Wine Polyphenolic Compounds on Platelet Function of Dietary-Induced Hypercholesterolemic Rats

Yuko Kobayashi, Akiko Yamada, Eri Murata, Yoshimi Shimizu, Mikako Kaga, Tomoko Shimoda, Tomomi Aita, Tsunekata Ito, Akira Ishihata, Yumi Katano

Bulletin of the Yamagata University. Medical science ( 山形大学 ) 26 ( 2 ) 61 - 68 2008.08

Hypercholesterolemia is an important risk factor of coronary heart diseases, in which platelet aggregability is enhanced. It is suggested that platelet aggregation is inhibited by red wine polyphenolic compounds (RWPC) in vitro. We investigated the effect of chronic administration of RWPC on platelet aggregation, plasma lipid levels and lipid deposition in liver in hypercholesterolemic rats. Male F344 rats (2 month-old) were fed standard diet (Cont), 4% cholesterol-rich-diet (Cho), or 4% cholesterol-rich-diet plus 0.62% freeze-dried red wine extracts (RWPC + Cho) for 1 month. Platelet aggre...

CiNii

食餌性高コレステロール血症ラットの血小板機能に対する赤ワインポリフェノール成分長期摂取の効果

小林優子, 山田晃子, 村田恵理, 清水良美, 利美賀子, 下田智子, 会田智美, 伊藤恒賢, 石幡明, 片野由美

山形医学 26 ( 5 ) 27 2008.02 [Refereed]

赤ワイン凍結乾燥品の長期投与による食餌性高コレステロール血症ラット血管機能の変化

清水良美, 五十嵐祐子, 利美賀子, 会田智美, 下田智子, 石幡明, 片野由美

未病システム学会雑誌 192 2008 [Refereed]

Progression of severe atherosclerosis and increased arterial pulse pressure in the newly developed heritable mixed hyperlipidaemic rabbits

T Shimoda, A Ishihata, T Aita, M Kaga, T Ito, K Ohwada, H Tomoike, Y Katano

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY ( BLACKWELL PUBLISHING ) 33 ( 3 ) 221 - 226 2006.03 [Refereed]

We have recently segregated a new line of rabbit, named TGH, with severely high levels of plasma triglyceride and cholesterol. The aim of the present study was to investigate the progression of atherosclerosis and haemodynamic parameters in TGH rabbits. Japanese white (JW) and TGH rabbits (24-27 months old) were anaesthetized with ketamine and xylazine. Plasma concentrations of triglyceride were 63.1 8.0 and 446.0 35.2 mg/dL in JW and TGH rabbits, respectively. Blood pressure was measured by a catheter implanted in the femoral artery. Histological examinations were performed using haematoxylin-eosin and elastica-Masson trichrome staining to detect atherosclerotic lesions. The JW rabbits had no atherosclerotic lesions. In TGH rabbits, severe atherosclerotic lesions were observed throughout the aorta, especially in the aortic arch. Basal femoral arterial pressure was not significantly different between JW and TGH rabbits. However, the basal pulse pressure in TGH rabbits (48.3 4.5 mmHg) was significantly greater than that of JW rabbits (28.0 5.6 mmHg). Intravenous infusion of N-G-nitro-L-arginine methyl ester (L-NAME; 26.9 mg/kg) increased the blood pressure of TGH and JW rabbits. There was no significant difference in the response to L-NAME between the two rabbit strains. The present study shows that severe atherosclerotic changes develop in TGH rabbits and suggests that the hyperlipidaemia combined with hypercholesterolaemia and hypertriglyceridaemia is an important factor for promoting atherosclerosis in TGH rabbits. The greater pulse pressure in TGH rabbits may be due to the increased vascular stiffness with atherosclerosis. This newly developed TGH rabbit line of heritable hypertriglyceridaemia with hypercholesterolaemia will become a useful animal model for studies on the role of hyperlipidaemia in the progression of atherosclerosis and in many atherosclerosis-related diseases.

DOI PubMed

Progression of Atherosclerosis and Femoral Arterial Blood Pressure in Heritable Hypertriglyceridemic Rabbits

Shimoda Tomoko, Ishihata Akira, Ito Tunekata

Bulletin of the Yamagata University. Medical science ( 山形大学 ) 23 ( 1 ) 17 - 32 2005.02 [Refereed]

[Objective] It has been reported that hypercholesterolemia plays a role in progression of atherosclerosis. Watanabe heritable hyperlipidemic rabbits have been used widely as a model of familial hypercholesterolemia with atherosclerosis, while the emerging data raised a possibility of an important role of hypertriglyceridemia in the pathogenesis of atherosclerosis. We have recently segregated a new line with severely high (TGH) and moderately high (TGL) levels of plasma triglyceride. The hemodynamic parameters of TGH and TGL are not defined. The aim of present study was to examine the progre...

CiNii

Extracts of Red Wine with Polyphenol Compounds Induce Endothelium-Dependent Vascular Relaxation in Aged Rat Aorta

Kaga Mikako, Ishihata Akira, Aita Tomomi

Bulletin of the Yamagata University. Medical science ( Yamagata University ) 23 ( 1 ) 33 - 41 2005.02 [Refereed]

[Objective] The vasorelaxing effects of the red wine extracts were studied in rat thoracic aorta. [Methods] Aortas were isolated from young (2-3 months) and aged (27 months) F344 rats and the ring preparations with or without endothelium were mounted in Krebs-Henseleit solution to measure the developed tension. The polyphenolic substances were added cumulatively after the contraction with phenylephrine.[Results] Extracts of red wine relaxed the vessels concentration-dependently. These vasorelaxant effects were attenuated by endothelial removal. In young rat, vasorelaxation induced by RWPC was significantly inhibited by L-NNA (100 μM), diclofenac (10 μM) and 30mM KCl. In aged rat, the inhibition by L-NNA and diclofenac was less than that of young rat, and 30mM KCl potently decreased the relaxation. However, the vasorelaxant responses were preserved even in aged aorta.[Conclusion] RWPC induces vascular relaxation endothelium-dependently not only in young rat but also in aged rat. The relaxation was mediated via NO, prostacyclin and EDHF in young aorta, while EDHF may play an important role in aged aorta.

CiNii

　 PREV - NEXT 　

<Tomoko UNO>

Papers - Tomoko UNO