2026/05/22 更新

写真a

トガシ アツオ
富樫 篤生
所属
医学部 感染制御・臨床検査医学講座 助教
職名
助教
ORCID ID
0000-0002-9532-0618
外部リンク

論文

  • Reemergence of Mycoplasma pneumoniae in Post-COVID-19 Japan: A 2024 Outbreak in Hokkaido After 5 Years. 査読 国際誌

    Yuya Fukuda, Atsuo Togashi, Satoshi Hirakawa, Masaki Yamamoto, Shinobu Fukumura, Tomohiro Nawa, Nana Kushima, Takahiro Maeda, Jun Kunizaki, Noritaka Shintani, Kouhei Nishino, Toshitaka Kizawa, Dai Yamamoto, Yoshiyuki Iizuka, Yuta Sasaoka, Masayoshi Kikuchi, Takuro Ito, Kazushige Nagai, Hirofumi Asakura, Yui Ito, Masaki Yoshida, Seiji Kobayashi, Takeshi Tsugawa

    The Pediatric infectious disease journal   44 ( 12 )   e473-e475   2025年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/INF.0000000000004927

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  • A significant outbreak of respiratory human adenovirus infections among children aged 3-6 years in Hokkaido, Japan, in 2023. 査読 国際誌

    Yuya Fukuda, Atsuo Togashi, Satoshi Hirakawa, Masaki Yamamoto, Shinobu Fukumura, Tomohiro Nawa, Nana Kushima, Satoshi Nakamura, Jun Kunizaki, Kouhei Nishino, Ryoma Kimura, Toshitaka Kizawa, Dai Yamamoto, Ryoh Takeuchi, Yuta Sasaoka, Masayoshi Kikuchi, Takuro Ito, Kazushige Nagai, Hirofumi Asakura, Sayaka Nishimura, Masaki Yoshida, Kousuke Tsuchida, Takeshi Tsugawa

    Journal of medical virology   96 ( 7 )   e29780   2024年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Human adenovirus (HAdV) infections present diverse clinical manifestations upon infecting individuals, with respiratory infections predominating in children. We surveyed pediatric hospitalizations due to respiratory HAdV infections across 18 hospitals in Hokkaido Prefecture, Japan, from July 2019 to March 2024, recording 473 admissions. While hospitalizations remained below five cases per week from July 2019 to September 2023, a notable surge occurred in late October 2023, with weekly admissions peaking at 15-20 cases from November to December. There were dramatic shifts in the age distribution of hospitalized patients: during 2019-2021, 1-year-old infants and children aged 3-6 years represented 51.4%-54.8% and 4.1%-13.3%, respectively; however, in 2023-2024, while 1-year-old infants represented 19.0%-20.1%, the proportion of children aged 3-6 years increased to 46.2%-50.0%. Understanding the emergence of significant outbreaks of respiratory HAdV infections and the substantial changes in the age distribution of hospitalized cases necessitates further investigation into the circulating types of HAdV in Hokkaido Prefecture and changes in children's neutralizing antibody titers against HAdV.

    DOI: 10.1002/jmv.29780

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  • Clinical usefulness of the "GeneSoC® SARS-CoV-2 N2 Detection Kit" 査読

    Yuki Sato, Takashi Kondo, Yuki Katayama, Natsuki Narumi, Atsuo Togashi, Yoshihiro Fujiya, Koji Kuronuma, Satoshi Takahashi

    JOURNAL OF LABORATORY MEDICINE   48 ( 2 )   91 - 95   2024年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1515/labmed-2023-0119

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  • Severe cervical abscess due to PVL-positive ST6562 MRSA-IVa, a presumptive variant of ST8-IVa USA300 clone in northern Japan. 査読 国際誌

    Katsumasa Kudo, Takahiro Noda, Yuta Sasaoka, Atsuo Togashi, Meiji Soe Aung, Yoshiyuki Sakai, Takeshi Tsugawa, Nobumichi Kobayashi

    New microbes and new infections   58   101230 - 101230   2024年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.nmni.2024.101230

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  • Resurgence of human metapneumovirus infection and influenza after three seasons of inactivity in the post-COVID-19 era in Hokkaido, Japan, 2022-2023. 査読 国際誌

    Yuya Fukuda, Atsuo Togashi, Satoshi Hirakawa, Masaki Yamamoto, Shinobu Fukumura, Tomohiro Nawa, Saho Honjo, Jun Kunizaki, Kouhei Nishino, Toju Tanaka, Toshitaka Kizawa, Dai Yamamoto, Ryoh Takeuchi, Yuta Sasaoka, Masayoshi Kikuchi, Takuro Ito, Kazushige Nagai, Hirofumi Asakura, Katsumasa Kudou, Masaki Yoshida, Takeshi Nishida, Takeshi Tsugawa

    Journal of medical virology   95 ( 12 )   e29299   2023年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Following the coronavirus disease 2019 (COVID-19) outbreak in February 2020, incidences of various infectious diseases decreased notably in Hokkaido Prefecture, Japan. However, Japan began gradually easing COVID-19 infection control measures in 2022. Here, we conducted a survey of children hospitalized with human metapneumovirus (hMPV), influenza A and B, and respiratory syncytial virus infections in 18 hospitals across Hokkaido Prefecture, Japan, spanning from July 2019 to June 2023. From March 2020 to June 2022 (28 months), only 13 patients were hospitalized with hMPV, and two patients had influenza A. However, in October to November 2022, there was a re-emergence of hMPV infections, with a maximum of 27 hospitalizations per week. From July 2022 to June 2023 (12 months), the number of hMPV-related hospitalizations dramatically increased to 317 patients, with the majority aged 3-6 years (38.2%, [121/317]). Influenza A also showed an increase from December 2022, with a peak of 13 hospitalizations per week in March 2023, considerably fewer than the pre-COVID-19 outbreak in December 2019, when rates reached 45 hospitalizations per week. These findings suggest the possibility of observing more resurgences in infectious diseases in Japan after 2023 if infection control measures continue to be relaxed. Caution is needed in managing potential outbreaks.

    DOI: 10.1002/jmv.29299

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  • Changing Patterns of Infectious Diseases Among Hospitalized Children in Hokkaido, Japan, in the Post-COVID-19 Era, July 2019 to June 2022. 査読 国際誌

    Yuya Fukuda, Atsuo Togashi, Satoshi Hirakawa, Masaki Yamamoto, Shinobu Fukumura, Tomohiro Nawa, Saho Honjo, Jun Kunizaki, Kouhei Nishino, Toju Tanaka, Toshitaka Kizawa, Dai Yamamoto, Ryoh Takeuchi, Yuta Sasaoka, Masayoshi Kikuchi, Takuro Ito, Kazushige Nagai, Hirofumi Asakura, Katsumasa Kudou, Masaki Yoshida, Takeshi Nishida, Takeshi Tsugawa

    The Pediatric infectious disease journal   42 ( 9 )   766 - 773   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Many reports have reported a reduction in respiratory infectious diseases and infectious gastroenteritis immediately after the coronavirus disease 2019 (COVID-19) pandemic, but data continuing into 2022 are very limited. We sought to understand the current situation of various infectious diseases among children in Japan as of July 2022 to improve public health in the post-COVID-19 era. METHODS: We collected data on children hospitalized with infectious diseases in 18 hospitals in Japan from July 2019 to June 2022. RESULTS: In total, 3417 patients were hospitalized during the study period. Respiratory syncytial virus decreased drastically after COVID-19 spread in early 2020, and few patients were hospitalized for it from April 2020 to March 2021. However, an unexpected out-of-season re-emergence of respiratory syncytial virus was observed in August 2021 (50 patients per week), particularly prominent among older children 3-6 years old. A large epidemic of delayed norovirus gastroenteritis was observed in April 2021, suggesting that the nonpharmaceutical interventions for COVID-19 are less effective against norovirus. However, influenza, human metapneumovirus, Mycoplasma pneumoniae , and rotavirus gastroenteritis were rarely seen for more than 2 years. CONCLUSIONS: The incidence patterns of various infectious diseases in Japan have changed markedly since the beginning of the COVID-19 pandemic to the present. The epidemic pattern in the post-COVID-19 era is unpredictable and will require continued careful surveillance.

    DOI: 10.1097/INF.0000000000003982

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  • Acute osteomyelitis/septic pulmonary embolism associated with familial infections caused by PVL-positive ST6562 MRSA-IVa, a presumptive variant of USA300 clone. 査読 国際誌

    Nao Harada, Atsuo Togashi, Meiji Soe Aung, Jun Kunizaki, Kazutaka Nogami, Yoshinobu Nagaoka, Akira Ishii, Ima Kosukegawa, Wakiko Aisaka, Satoshi Nakamura, Tomohiro Wakabayashi, Takeshi Tsugawa, Nobumichi Kobayashi

    IJID regions   8   16 - 18   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA) occasionally causes severe invasive infections. A 10-year-old immunocompetent boy in Hokkaido, the northern main island of Japan, was admitted with acute osteomyelitis of the right ilium, complicated by septic thrombophlebitis of the right common iliac vein and septic pulmonary embolism. As MRSA was isolated from blood and sputum samples of the patient, linezolid and vancomycin were initially used for treatment, and later clindamycin was added based on PCR-positive results for PVL genes. During his hospitalization, the patient was complicated by abscesses around the right ilium and septic arthritis of the right hip, which required surgical drainage. Prior to his admission, his youngest sister had developed a right breast abscess, and another sister and his mother developed contagious impetigo and hordeolum, respectively, during his hospitalization. These infections in the patient and his family members were caused by an identical PVL-positive MRSA strain belonging to ST6562, a single-locus variant of ST8. Due to the genetically close characteristics, this ST6562 MRSA was considered a genetic variant of the USA300 CA-MRSA clone (ST8-MRSA-IVa) predominating in the United States. The ST6562 MRSA-IVa is suggested to have occurred in Japan, associated with potential spread of the USA300 clone.

    DOI: 10.1016/j.ijregi.2023.05.006

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  • Factors affecting the sensitivity of quantitative severe acute respiratory syndrome coronavirus 2 antigen test. 査読 国際誌

    Yuki Sato, Ryosei Murai, Ryo Kobayashi, Atsuo Togashi, Yoshihiro Fujiya, Koji Kuronuma, Satoshi Takahashi

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   29 ( 8 )   754 - 758   2023年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    INTRODUCTION: The accuracy of nucleic acid amplification tests (NAATs) is affected by various factors; however, studies examining the factors affecting the accuracy of quantitative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen test (QAT) are limited. METHODS: A total of 347 nasopharyngeal samples were collected from patients with coronavirus disease 2019 (COVID-19), and the date of onset was obtained from the electronic medical records. The SARS-CoV-2 antigen level was measured using Lumipulse Presto SARS-CoV-2 Ag (Presto), while NAAT was performed using the Ampdirect 2019-nCoV Detection Kit. RESULTS: Presto had a sensitivity rate of 95.1% (95% confidence interval: 92.8-97.4) in detecting the SARS-CoV-2 antigen in 347 samples. The number of days from symptom onset to sample collection was negatively correlated with the amount of antigen (r = -0.515) and sensitivity of Presto (r = -0.711). The patients' age was lower in the Presto-negative samples (median age, 39 years) compared with that in the Presto-positive samples (median age, 53 years; p < 0.01). A significant positive correlation was observed between age (excluding teenagers) and Presto sensitivity (r = 0.764). Meanwhile, no association was found between the mutant strain, sex, and Presto results. CONCLUSION: Presto is useful for the accurate diagnosis of COVID-19 owing to its high sensitivity when the number of days from symptom onset to sample collection is within 12 days. Furthermore, age may affect the results of Presto, and this tool has a relatively low sensitivity in younger patients.

    DOI: 10.1016/j.jiac.2023.04.005

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  • Correlation between antibiotic use and antibiotic resistance: A multicenter study using the Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system in Hokkaido, Japan. 査読 国際誌

    Keisuke Kagami, Nobuhisa Ishiguro, Sumio Iwasaki, Takayuki Usami, Tatsuya Fukumoto, Kasumi Hayasaka, Reiko Oyamada, Tsubasa Watanabe, Sho Nakakubo, Yusuke Niinuma, Takashi Hagino, Yoshifumi Abe, Ikuya Fujimoto, Hideki Maekawa, Ryo Fujibayashi, Satoshi Fuke, Kuniko Asahi, Shuichi Ota, Tatsuya Nagakura, Toshinari Okubo, Hideomi Asanuma, Toshihiro Ito, Sho Okano, Erika Komatsu, Kota Sasaki, Kei Hashimoto, Kazutoshi Washiya, Yumiko Kato, Katsunori Kusumi, Yasufumi Asai, Yuichi Saito, Yoshiyuki Sakai, Minoru Sakurada, Yuji Sakimoto, Yukari Ichikawa, Takahiro Kinebuchi, Dai Kondo, Syuhei Kanno, Minoru Kobayashi, Kagami Hirabayashi, Shinako Saitou, Katsuhiko Saito, Yuuki Ebina, Yuusuke Koshizaki, Makoto Chiba, Atsushi Yasuda, Toshiya Sato, Atsuo Togashi, Takashi Abe, Takahiro Fujita, Kengo Umehara, Masaru Amishima, Nobuo Murakami, Tetsuya Yagi, Shuhei Fujimoto, Taichi Tajima, Mitsuru Sugawara, Yoh Takekuma

    American journal of infection control   51 ( 2 )   163 - 171   2023年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system aggregates information related to antimicrobial resistance (AMR) measures in participating medical institutions nationwide and is intended to be used for promotion of AMR measures in participating facilities and their communities. This multicenter study aimed to determine the usefulness of the J-SIPHE system for evaluating the correlation between antibiotic use and antibiotic resistance in Hokkaido, Japan. METHODS: Data on antibiotic use and detection rate of major resistant Gram-negative bacteria at 19 hospitals in 2020 were collected from the J-SIPHE system, and data correlations were analyzed using JMP Pro. RESULTS: The detection rate of carbapenem-resistant Pseudomonas aeruginosa was significantly positively correlated with carbapenem use (Spearman's ρ = 0.551; P = .015). There were significant positive correlations between the detection rate of fluoroquinolone-resistant Escherichia coli and the use of piperacillin/tazobactam, carbapenems, and quinolones [ρ = 0.518 (P = .023), ρ = 0.76 (P < .001), and ρ = 0.502 (P = .029), respectively]. CONCLUSIONS: This is the first multicenter study to investigate the correlation between antibiotic use and antibiotic resistance using the J-SIPHE system. The results suggest that using this system may be beneficial for promoting AMR measures.

    DOI: 10.1016/j.ajic.2022.05.025

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  • Sequence analysis of a feline- and porcine-origin G3P[9] rotavirus A strain in a child with acute gastroenteritis in Japan. 査読 国際誌

    Yuya Fukuda, Kaoru Araki, Megumi Hara, Yuji Yamashita, Shuhei Adachi, Saho Honjo, Atsuo Togashi, Satoshi Hirakawa, Shinobu Fukumura, Masaki Yamamoto, Takeshi Tsugawa

    Archives of virology   168 ( 2 )   45 - 45   2023年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    We isolated the rare G3P[9] rotavirus strain RVA/Human-wt/JPN/R11-035/2015/G3P[9] from a 2-year-old girl presenting with vomiting and diarrhea who had daily contact with cats in Japan, 2015. Full-genome analysis revealed that the R11-035 strain had an AU-1-like genetic constellation, except for the NSP3 (T) gene: G3-P[9]-I3-R3-C3-M3-A3-N3-T1-E3-H6. Phylogenetic analysis showed that strain R11-035 is closely related to human/feline-like human strains, and only the NSP3 (T1) gene was clustered together with Taiwanese porcine strains. We postulate that the R11-035 strain was directly transmitted from a cat to the patient and acquired its NSP3 gene through intergenotype reassortment with porcine strains before being transmitted to humans.

    DOI: 10.1007/s00705-022-05685-3

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  • 思春期3疾患は増えているか?

    佐藤 俊哉, 三木 芳織, 富樫 篤生, 藤根 美穂

    岩見沢市立総合病院医誌   48 ( 1 )   1 - 3   2022年7月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

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  • 市中病院新生児室における入院時体表監視培養の意義

    富樫 篤生, 宮川 康宏, 三木 芳織, 佐藤 俊哉

    臨床小児医学   69 ( 1-6 )   15 - 21   2022年3月

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    記述言語:日本語   出版者・発行元:(財)小児愛育協会  

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  • Surveillance in hospitalized children with infectious diseases in Japan: Pre- and post-coronavirus disease 2019. 査読 国際誌

    Yuya Fukuda, Takeshi Tsugawa, Yoshinobu Nagaoka, Akira Ishii, Tomohiro Nawa, Atsuo Togashi, Jun Kunizaki, Satoshi Hirakawa, Junya Iida, Toju Tanaka, Toshitaka Kizawa, Dai Yamamoto, Ryoh Takeuchi, Yoshiyuki Sakai, Masayoshi Kikuchi, Kazushige Nagai, Hirofumi Asakura, Rina Tanaka, Masaki Yoshida, Ryo Hamada, Yukihiko Kawasaki

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   27 ( 11 )   1639 - 1647   2021年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    INTRODUCTION: The epidemic of coronavirus disease 2019 (COVID-19) rapidly spread worldwide, and the various infection control measures have a significant influence on the spread of many infectious diseases. However, there have been no multicenter studies on how the number of hospitalized children with various infectious diseases changed before and after the outbreak of COVID-19 in Japan. METHODS: We conducted a multicenter, prospective survey for hospitalized pediatric patients in 18 hospitals in Hokkaido Prefecture, Japan, from July 2019 to February 2021. We defined July 2019 to February 2020 as pre-COVID-19, and July 2020 to February 2021 as post-COVID-19. We surveyed various infectious diseases by sex and age. RESULTS: In total, 5300 patients were hospitalized during the study period. The number of patients decreased from 4266 in the pre-COVID-19 period to 701 (16.4%) post-COVID-19. Patients with influenza and RSV decreased from 308 to 795 pre-COVID-19 to zero and three (0.4%) post-COVID-19. However, patients with adenovirus (respiratory infection) only decreased to 60.9% (46-28) of pre-COVID levels. Patients with rotavirus, norovirus, and adenovirus gastroenteritis decreased markedly post-COVID-19 to 2.6% (38-1), 27.8% (97-27) and 13.5% (37-5). The number of patients with UTIs was similar across the two periods (109 and 90). KD patients decreased to 31.7% (161-51) post-COVID-19. CONCLUSIONS: We suggest that current infection control measures for COVID-19 such as wearing masks, washing hands, and disinfecting hands with alcohol are effective against various infectious diseases. However, these effects vary by disease.

    DOI: 10.1016/j.jiac.2021.07.024

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  • A rare pathogen Raoultella planticola caused urinary tract infection in child with congenital anomalies of kidney and urinary tract: case report. 査読 国際誌

    Yuya Fukuda, Shuhei Adachi, Makoto Saito, Reikichi Shoji, Atsuo Togashi

    Translational pediatrics   10 ( 9 )   2387 - 2391   2021年9月

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    担当区分:最終著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Raoultella planticola was previously considered an environmental organism in soil, water, and plants. However, several cases of human infection have recently been reported in association with R. planticola, some of which have been life-threatening. Most cases were in adults with reduced immunity, with few cases in children. To our knowledge, there have only been two reported cases of urinary tract infection (UTI) caused by R. planticola in children, including one case of cystitis. Here, we present the first case of UTI caused by R. planticola with congenital anomalies of kidney and urinary tract (CAKUT) in a 4-month-old male infant. The patient presented to the emergency department with fever and was diagnosed with UTI. We started third-generation cephalosporins empirically for gram-negative bacteria in the urine, presuming infection with Escherichia coli. On day 1, the patient's fever resolved immediately. On day 2, urine culture was positive for a rare pathogen, R. planticola, and we narrowed antibiotics to first-generation cephalosporins. The patient's fever did not return and he was discharged on day 7. The patient was seen in the clinic 1 week after discharge, with complete resolution of symptoms. Magnetic resonance urography and dynamic renal scintigraphy performed 2 months after discharge revealed severe bilateral hydronephroureter and obstruction of urine flow in the right kidney. As of 6 months after UTI onset, we have continued low-dose cephalexin (10 mg/kg) to prevent the recurrence of UTI and there has been no recurrence. As in this case, children with UTI caused by R. planticola may be associated with CAKUT; therefore, we should actively screen to detect CAKUT. Patients with CAKUT are at high risk of UTI recurrence, so long-term use of unnecessary broad-spectrum antibiotics should be avoided to prevent antimicrobial resistance. However, R. planticola infection is sometimes life-threatening. Hence, it is also important to use sufficiently strong antibiotics for an appropriate period. Although the optimal management of R. planticola infection in children has not been clearly established, we suggest that we can treat UTI caused by R. planticola mainly using first-generation cephalosporins.

    DOI: 10.21037/tp-21-170

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  • PCR-核酸クロマトグラフィー法による下痢原性大腸菌検出の検討

    宮川 康宏, 築城 裕和, 山田 理絵, 寺田 愛, 富樫 篤生

    岩見沢市立総合病院医誌   46 ( 1 )   3 - 7   2020年7月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

    医中誌

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  • 小児QT延長の4例

    佐藤 俊哉, 末岡 秀文, 串間 奈々, 富樫 篤生, 小野寺 慧洲, 會澤 佳昭, 東出 侑子, 名和 智裕, 高室 基樹, 横澤 正人, 和田 励, 春日 亜衣, 望月 敦史

    岩見沢市立総合病院医誌   45 ( 1 )   3 - 5   2019年6月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

    医中誌

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  • 当院の侵襲性カンジダ症の原因菌種と抗真菌剤の選択

    向井 将之, 富樫 篤生, 高木 祐之, 阿部 珠子, 坂下 路絵, 佐藤 俊哉

    岩見沢市立総合病院医誌   45 ( 1 )   7 - 10   2019年6月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

    医中誌

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  • 当院に入院した小児上部尿路感染症の起炎菌と感受性の検討

    富樫 篤生, 末岡 秀文, 藤根 美穂, 佐藤 俊哉

    岩見沢市立総合病院医誌   45 ( 1 )   19 - 22   2019年6月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

    医中誌

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  • 培養株を用いたC.デイフィシル感染症診断の取り組み

    佐藤 俊哉, 富樫 篤生, 高木 裕之, 阿部 珠子, 坂下 路絵, 向井 将之

    岩見沢市立総合病院医誌   45 ( 1 )   1 - 2   2019年6月

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    記述言語:日本語   出版者・発行元:岩見沢市立総合病院  

    医中誌

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  • Tetanus in a partially immunized child. 査読 国際誌

    Yusuke Akane, Takeshi Tsugawa, Tsukasa Hori, Atsuo Togashi, Yuko Yoto, Natsuko Inazawa, Nozomi Ito, Ryoko Kyan, Mitsutoshi Senoh, Haru Kato, Hiroyuki Tsutsumi

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   24 ( 12 )   980 - 982   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    A 13-year-old boy developed tetanus, although he had protective antitoxin antibody raised by three doses of tetanus toxoid vaccine. Four days after injury, he presented with muscle rigidity of his posterior neck, excessive diaphoresis, and risus sardonicus and was subsequently diagnosed with tetanus. Tetanus is rare in developed countries, particularly during childhood, but must be promptly diagnosed based on clinical symptoms.

    DOI: 10.1016/j.jiac.2018.05.002

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  • Septic arthritis caused by an emerging ST121 methicillin-susceptible, PVL-negative Staphylococcus aureus harbouring a variant of bone sialoprotein-binding protein gene 査読

    A. Togashi, M.S. Aung, Y. Yoto, T. Tsugawa, H. Sueoka, M. Kawaguchiya, H. Tsutsumi, N. Kobayashi

    New Microbes and New Infections   19   17 - 18   2017年9月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    DOI: 10.1016/j.nmni.2017.05.010

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