Papers - YOKOTA Shinichi

Molecular Epidemiology of Fluoroquinolone-resistant Streptococcus pneumoniae in apan

横田伸一, 佐藤清, 吉田繁, 藤井暢弘

感染症学雑誌   78 ( 5 ) 428 - 34  2004  [Refereed]

J-GLOBAL

Suppression of thermotolerance in mumps virus-infected cells is caused by lack of HSP27 induction contributed by STAT-1

S Yokota, N Yokosawa, T Kubota, T Okabayashi, S Arata, N Fujii

JOURNAL OF BIOLOGICAL CHEMISTRY   278 ( 43 ) 41654 - 41660  2003.10  [Refereed]

DOI PubMed CiNii

Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease

SI Yokota, H Kubota, Y Matsuoka, M Naitoh, D Hirata, S Minota, TID Hiroki, N Fujii, K Nagata

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   303 ( 2 ) 413 - 418  2003.04  [Refereed]

DOI PubMed CiNii

Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines

N Yonekura, S Yokota, K Yonekura, H Dehari, S Arata, G Kohama, N Fujii

CELL DEATH AND DIFFERENTIATION   10 ( 3 ) 313 - 322  2003.03  [Refereed]

DOI

Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex

S Yokota, H Saito, T Kubota, N Yokosawa, K Amano, N Fujii

VIROLOGY   306 ( 1 ) 135 - 146  2003.02  [Refereed]

DOI PubMed CiNii

Association of mumps virus V protein with RACK1 results in dissociation of STAT-1 from the alpha interferon receptor complex

T Kubota, N Yokosawa, S Yokota, N Fujii

JOURNAL OF VIROLOGY   76 ( 24 ) 12676 - 12682  2002.12  [Refereed]

DOI PubMed CiNii

C-terminal region of STAT-1 alpha is not necessary for its ubiquitination and degradation caused by mumps virus V protein

N Yokosawa, S Yokota, T Kubota, N Fujii

JOURNAL OF VIROLOGY   76 ( 24 ) 12683 - 12690  2002.12  [Refereed]

DOI PubMed CiNii

Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan

S Yokota, K Sato, O Kuwahara, S Habadera, N Tsukamoto, H Ohuchi, H Akizawa, T Himi, N Fujii

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   46 ( 10 ) 3311 - 3315  2002.10  [Refereed]

DOI

Increased expression of cytosolic chaperonin CCT in human hepatocellular and colonic carcinoma

S Yokota, Y Yamamoto, K Shimizu, H Momoi, T Kamikawa, Y Yamaoka, H Yanagi, T Yura, H Kubota

CELL STRESS & CHAPERONES   6 ( 4 ) 345 - 350  2001.10  [Refereed]

Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle

S Yokota, H Yanagi, T Yura, H Kubota

EUROPEAN JOURNAL OF BIOCHEMISTRY   268 ( 17 ) 4664 - 4673  2001.09  [Refereed]

DOI PubMed CiNii

Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and janus kinases during an early infection stage

S Yokota, N Yokosawa, T Kubota, T Suzutani, Yoshida, I, S Miura, K Jimbow, N Fujii

VIROLOGY ( ACADEMIC PRESS INC )  286 ( 1 ) 119 - 124  2001.07  [Refereed]

　View Summary

We examined the influence on the interferon (IFN) signaling pathway of infection with herpes simplex virus type 1 (HSV-1 strain VR3. Data from reporter gene assays showed that expression of both type I and type II IFN-inducible genes was dramatically suppressed during the early stage of HSV-1 infection (2 to 3 h postinfection). During these periods, phosphorylation levels of janus kinases (JAKs) and STATs did not increase after treatment of HSV-1-infected FL cells with IFN-alpha or IFN-gamma, although cellular protein levels of the JAKs and the sTATs were not significantly changed. In contrast, the inhibitory effect of HSV-1 on phosphorylation of STAT1 was not observed in U937 cells, which show resistance to steady-state accumulation of RNA for HSV-1 immediate-early genes. The phosphorylation of STAT1 in FL cells was not inhibited by infection with a UV-inactivated virus. These results indicate that Viral gene expression or viral protein production is necessary for the inhibition of phosphorylation by HSV-1. (C) 2001 Academic Press.

DOI PubMed CiNii

C terminal CYS-RICH region of mumps virus structural v protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alpha

T Kubota, N Yokosawa, S Yokota, N Fujii

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   283 ( 1 ) 255 - 259  2001.04  [Refereed]

DOI PubMed CiNii

Proteasome-dependent degradation of cytosolic chaperonin CCT

S Yokota, T Kayano, T Ohta, M Kurimoto, H Yanagi, T Yura, H Kubota

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   279 ( 2 ) 712 - 717  2000.12  [Refereed]

DOI PubMed CiNii

Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins

S Yokota, D Hirata, S Minota, T Higashiyama, M Kurimoto, H Yanagi, T Yura, H Kubota

CELL STRESS & CHAPERONES   5 ( 4 ) 337 - 346  2000.10  [Refereed]

Transcriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteins

H Kubota, S Yokota, H Yanagi, T Yura

JOURNAL OF BIOLOGICAL CHEMISTRY   275 ( 37 ) 28641 - 28648  2000.09  [Refereed]

DOI PubMed CiNii

Expression of histo-blood group antigens by lipopolysaccharides of Helicobacter pylori strains from Asian hosts: the propensity to express type 1 blood-group antigens

MA Monteiro, P Zheng, B Ho, S Yokota, K Amano, Z Pan, DE Berg, KH Chan, LL MacLean, MB Perry

GLYCOBIOLOGY   10 ( 7 ) 701 - 713  2000.07  [Refereed]

DOI PubMed CiNii

Comparison of serum antibody titers to Helicobacter pylori lipopolysaccharides, CagA, VacA and partially purified cellular extracts in a Japanese population

S Yokota, K Amano, N Fujii, T Yokochi

FEMS MICROBIOLOGY LETTERS   185 ( 2 ) 193 - 198  2000.04  [Refereed]

DOI PubMed CiNii

Upregulation of cytosolic chaperonin CCT subunits during recovery from chemical stress that causes accumulation of unfolded proteins

S Yokota, H Yanagi, T Yura, H Kubota

EUROPEAN JOURNAL OF BIOCHEMISTRY   267 ( 6 ) 1658 - 1664  2000.03  [Refereed]

DOI PubMed CiNii

Two distinct antigenic types of the polysaccharide chains of Helicobacter pylori lipopolysaccharides characterized by reactivity with sera from humans with natural infection

S Yokota, K Amano, Y Shibata, M Nakajima, M Suzuki, S Hayashi, N Fujii, T Yokochi

INFECTION AND IMMUNITY   68 ( 1 ) 151 - 159  2000.01  [Refereed]

Cytosolic chaperonin is up-regulated during cell growth - Preferential, expression and binding to tubulin at G(1)/S transition through early S phase

S Yokota, H Yanagi, T Yura, H Kubota

JOURNAL OF BIOLOGICAL CHEMISTRY   274 ( 52 ) 37070 - 37078  1999.12  [Refereed]

DOI PubMed CiNii