Organization
School of Medicine Department of Diagnostic Radiology Associate Professor
Title
Associate Professor
External link
YAMA Naoya
Research Interests
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組織幹細胞
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肝臓外科学
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肝再生
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肝予備能
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組織肝細胞
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細胞移植
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肝予備機能
Research Areas
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Life Science / Digestive surgery
Research History
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Sapporo Medical University School of Medicine Assistant Professor
2012
Papers
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Asialoglycoprotein receptor scintigraphy with Tc-99m-galactosyl human serum albumin (Tc-99m-GSA) as an early predictor of survival in acute liver failure Reviewed
H. Tatsumi, Y. Masuda, H. Imaizumi, S. Yoshida, K. Goto, N. Yama, T. Mizuguchi, K. Hirata
ANAESTHESIA AND INTENSIVE CARE 41 ( 4 ) 523 - 528 2013.7
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腎被膜原発平滑筋腫の1例
北川 未央, 玉川 光春, 兵頭 秀樹, 兵頭 かずさ, 山 直也, 河合 有里子, 佐藤 大志, 荒谷 和紀, 小野寺 麻希, 笠原 理子, 鷲尾 嘉一, 斎藤 正人, 晴山 雅人, 舛森 直哉, 塚本 泰司
Japanese Journal of Radiology 31 ( Suppl.I ) 7 - 7 2013.2
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MRIによる前立腺癌の浸潤進展度の評価
荒谷 和紀, 玉川 光春, 兵頭 秀樹, 兵頭 かずさ, 山 直也, 河合 有里子, 佐藤 大志, 小野寺 麻希, 笠原 理子, 鷲尾 嘉一, 斎藤 正人, 北川 未央, 晴山 雅人, 田中 俊明, 舛森 直哉, 塚本 泰司
Japanese Journal of Radiology 31 ( Suppl.I ) 7 - 7 2013.2
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A retrospective study on the transition of radiation dose rate and iodine distribution in patients with I-131-treated well-differentiated thyroid cancer to improve bed control shorten isolation periods Reviewed
Naoya Yama, Koh-ichi Sakata, Hideki Hyodoh, Mitsuharu Tamakawa, Masato Hareyama
ANNALS OF NUCLEAR MEDICINE 26 ( 5 ) 390 - 396 2012.6
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喉頭癌の軟骨浸潤の評価
北川 未央, 玉川 光春, 兵頭 秀樹, 兵頭 かずさ, 山 直也, 佐藤 大志, 河合 友里子, 晴山 雅人, 畠中 正光, 長谷川 匡
日本医学放射線学会学術集会抄録集 71回 S339 - S339 2012.2
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Aiで同定された内因性くも膜下出血 病理解剖所見との対比
北川 未央, 兵頭 秀樹, 佐藤 大志, 兵頭 かずさ, 山 直也, 河合 有里子, 荒谷 和紀, 笠原 理子, 鷲尾 嘉一, 浅井 真由美, 玉川 光春, 晴山 雅人, 成松 英智, 宮田 圭, 蕨 玲子
日本医学放射線学会秋季臨床大会抄録集 46回 S510 - S510 2010.8
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Assessment of Dural Arteriovenous Fistulas of the Cavernous Sinuses on 3D Dynamic MR Angiography Reviewed
H. Akiba, M. Tamakawa, H. Hyodoh, K. Hyodoh, T. Nonaka, Y. Minamida, M. Hashimoto, M. Hareyama
AMERICAN JOURNAL OF NEURORADIOLOGY 29 ( 9 ) 1652 - 1657 2008.10
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Technetium Tc 99m methylene diphosphonate bone scintigraphy of rhabdomyolysis after near-drowning in cold seawater Reviewed
Naoya Yama, Kazumitsu Koito, Kenji Fujimori, Masato Hareyama, Seiji Yoneta, Satoshi Nara, Yoshihiko Kurimoto, Eichi Narimatsu, Yasufumi Asai
AMERICAN JOURNAL OF EMERGENCY MEDICINE 25 ( 7 ) 848 - 850 2007.9
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Double-subtraction maximum intensity projection MR angiography for detecting the artery of Adamkiewicz and differentiating it from the drainage vein Reviewed
Hideki Hyodoh, Ryuji Shirase, Hidenari Akiba, Mitsuharu Tamakawa, Kazusa Hyodoh, Naoya Yama, Takaharu Shonai, Masato Hareyama
JOURNAL OF MAGNETIC RESONANCE IMAGING 26 ( 2 ) 359 - 365 2007.8
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【あなたのそばにもIPMN】こうみえるIPMN 放射線学的画像診断
小井戸 一光, 廣川 直樹, 佐藤 大志, 斉藤 正人, 山 直也, 晴山 雅人, 西田 睦
消化器内視鏡 19 ( 8 ) 1081 - 1087 2007.8
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The value of multidetector row computed tomography in the diagnosis of traumatic clivus epidural hematoma in children: A three-year experience Reviewed
Naoya Yama, Hitoshi Kano, Satoshi Nara, Yoshihiko Kurimoto, Eichi Narimatsu, Kazumitsu Koito, Yasufumi Asai, Masato Hareyama
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 62 ( 4 ) 898 - 901 2007.4
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Out-of-hospital cardiopulmonary arrest due to penetrating cardiac injury treated by percutaneous cardiopulmonary support in the emergency room: Report of a case Reviewed
Yoshihiko Kurimoto, Hitoshi Kano, Naoya Yama, Satoshi Nara, Mamoru Hase, Yasufumi Asai
SURGERY TODAY 37 ( 3 ) 240 - 242 2007.3
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【膵疾患の画像診断 最近のトレンド】膵疾患の超音波診断 最近の進歩
小井戸 一光, 廣川 直樹, 堀 正和, 佐藤 大志, 宇佐見 陽子, 山 直也, 晴山 雅人, 西田 睦
臨床画像 22 ( 12 ) 1323 - 1333 2006.12
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Blind subxiphold pericardiotomy for cardiac tamponade because of acute hemopericardium Reviewed
Yoshihiko Kurimoto, Mamoru Hase, Satoshi Nara, Naoya Yama, Nobuyoshi Kawaharada, Kiyofumi Morishita, Tetsuya Higami, Yasufumi Asai
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 61 ( 3 ) 582 - 585 2006.9
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Initial experiences in management of blunt aortic injury taking associated brain injury into consideration Reviewed
Y Kurimoto, K Morishita, N Kawaharada, J Fukada, Y Hachiro, Y Fujisawa, T Saitoh, N Yama, M Hase, E Narimatsu, Y Asai
CIRCULATION JOURNAL 70 ( 2 ) 198 - 201 2006.2
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Nominal free air in the left inguinal fossa due to perforation of the sigmoid colon in a case of blunt abdominal trauma: CT diagnosis Reviewed
N Yama, Y Kimura, H Tatsumi, C Kihara, Y Kurimoto, E Narimatsu, H Ura, K Koito, Y Asai, K Hirata, M Hreyama
ABDOMINAL IMAGING 31 ( 1 ) 57 - 58 2006.1
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Tumors of bone and soft tissue
Mitsuharu Tamagawa, H. Akiba, H. Hyodoh, K. Hyodoh, N. Yama, Y. Kawaai, T. Sato, M. Hareyama
Japanese Journal of Clinical Radiology 51 ( 2 ) 255 - 267 2006
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Preliminary report of contrast-enhanced computed tomography for patients with a percutaneous cardiopulmonary support system Reviewed
N Yama, Y Takeyama, K Tanno, S Nara, Y Itoh, K Mori, M Hase, Y Kurimoto, E Narimatsu, K Koito, Y Asai, M Hareyama
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 29 ( 6 ) 760 - 764 2005.11
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Tracheal bronchus mimicking bronchial intubation endoscopically: report of a case with airway burn Reviewed
N Yama, K Koito, M Hareyama, S Nara, H Okamoto, Y Kurimoto, E Narimatsu, Y Asai
AMERICAN JOURNAL OF EMERGENCY MEDICINE 23 ( 6 ) 815 - 816 2005.10
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Localization of intestinal bleeding using a fusion of Tc-99m-labeled RBC SPELT and X-ray CT Reviewed
N Yama, E Ezoe, Y Kimura, M Mukaiya, K Fujimori, Y Kurimoto, K Koito, K Hirata, M Hareyama, Y Asai
CLINICAL NUCLEAR MEDICINE 30 ( 7 ) 488 - 489 2005.7
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A paratracheal cystic lesion in a patient with potential high-energy trauma Reviewed
E Narimatsu, N Yama, W Danjoh, Y Kurimoto, Y Asai
JOURNAL OF EMERGENCY MEDICINE 28 ( 3 ) 333 - 335 2005.4
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Enhanced sonography using carbon dioxide gas for small hepatocellular carcinoma: A comparison study between pure carbon dioxide gas and carbon dioxide microbubbles Reviewed
Kazumitsu Koito, Tsutomu Namieno, Naoki Hirokawa, Takeshi Ichimura, Mutsumi Nishida, Naoya Yama, Koichi Sakata, Masato Hareyama, Motoi Nishi
Radiation Medicine - Medical Imaging and Radiation Oncology 23 ( 2 ) 104 - 110 2005.3
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Phase shift due to inversion recovery process and chemical shift effect in inversion recovery prepared gradient-echo magnetic resonance imaging Reviewed
Naoya Yama, Miki Takeda, Mitsuharu Tamakawa, Hidenari Akiba, Kazumitsu Koito, Masato Hareyama
Radiation Medicine - Medical Imaging and Radiation Oncology 23 ( 1 ) 56 - 60 2005.2
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A case of anomalous subaortic left brachiocephalic vein mimicking mediastinal hematoma Reviewed
N Yama, S Nara, Y Itoh, Y Kurimoto, E Narimatsu, Y Asai, K Koito, M Hareyama
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 58 ( 2 ) 419 - 420 2005.2
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MDCTによる膵癌・胆管癌の進展度診断 切除例での検討
市村 健, 小井戸 一光, 廣川 直樹, 西田 睦, 秋葉 英成, 玉川 光春, 兵頭 秀樹, 兵頭 かずさ, 武 美貴, 山 直也, 庄内 孝春, 佐藤 大志, 土本 正, 晴山 雅人, 平野 透
日本医学放射線学会雑誌 64 ( 8 ) 580 - 580 2004.11
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A simple but useful method of screening for mesenteric ischemia secondary to acute aortic dissection Reviewed
Y Kurimoto, K Morishita, J Fukada, N Kawaharada, K Komatsu, N Yama, Y Asai, T Abe
SURGERY 136 ( 1 ) 42 - 46 2004.7
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【単純・X線/CT これを見落としてはいけない】小腸 外傷性消化管穿孔
山 直也, 浦 英樹, 佐藤 大志, 廣川 直樹, 西田 睦, 小井戸 一光, 晴山 雅人, 江副 英理, 鹿野 恒, 栗本 義彦, 成松 英智, 浅井 康文
消化器の臨床 7 ( 3 ) 246 - 248 2004.6
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ED placement of arterial sheath for endovascular management in multiple trauma. Reviewed
Yama N, Ichimura T, Hirokawa N, Koito K, Hareyama M, Naito Y, Sasaki S, Yonemasu Y, Asai Y
The American journal of emergency medicine 22 245 - 246 2004.5
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造影超音波による肝血流評価 造影超音波の後期相が診断に有用であった肝結節性病変の1例
西田 睦, 小井戸 一光, 市村 健, 廣川 直樹, 堀 正和, 中田 健生, 山 直也, 庄内 孝春, 兵頭 秀樹, 晴山 雅人, 小関 至, 高木 秀安, 佐々木 茂, 今井 浩三, 池田 英之, 佐藤 昌明, 神代 正道
北海道医学雑誌 79 ( 2 ) 206 - 206 2004.4
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肝腫瘤性血流の経時的変化 造影超音波にて興味ある造影効果を示した硬化型肝細胞癌の1例
西田 睦, 小井戸 一光, 市村 健, 廣川 直樹, 佐藤 大志, 中田 健生, 山 直也, 庄内 孝春, 兵頭 秀樹, 玉川 光春, 晴山 雅人, 小関 至, 高木 秀安, 佐々木 茂, 今井 浩三, 木村 幸子, 佐藤 昌明
北海道医学雑誌 79 ( 2 ) 201 - 201 2004.4
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Pericardial hemorrhage secondary during computed tomography scanning for aortic dissecting aneurysm Reviewed
N Yama, H Hyhodo, K Koito, M Hareyama, N Kawaharada, K Morishita, T Abe, Y Takeyama, Y Kurimoto, Y Itoh, Y Asai
AMERICAN JOURNAL OF EMERGENCY MEDICINE 21 ( 6 ) 512 - 513 2003.10
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Assessment of stent-grafting for aortic dissection using multislice computed tomography. Reviewed
Kiromoto Y, Yama N, Marishita K, Asai Y, Abe T
The Annals of thoracic surgery 76 947 2003.9
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Thoracic involvement of type A aortic dissection and intramural hematoma: Diagnostic accuracy - Comparison of emergency helical CT and surgical findings Reviewed
S Yoshida, H Akiba, M Tamakawa, N Yama, M Hareyama, K Morishita, T Abe
RADIOLOGY 228 ( 2 ) 430 - 435 2003.8
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造影超音波による腎動静脈瘻・脾動脈瘤塞栓術の治療効果判定
西田 睦, 市村 健, 廣川 直樹, 小井戸 一光, 中田 健生, 山 直也, 庄内 孝春, 兵頭 秀樹, 晴山 雅人, 奈良 和彦
超音波医学 30 ( 4 ) J565 - J566 2003.7
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造影超音波によって嚢胞壁在結節が明瞭となった膵IPMTの1例
宇佐見 陽子, 小井戸 一光, 荒谷 和紀, 小島 一男, 高木 克, 廣川 直樹, 市村 健, 中田 健生, 庄内 孝春, 山 直也, 兵頭 秀樹, 西田 睦
超音波医学 30 ( 2 ) J237 - J237 2003.3
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Efficacy of SPIO-MR imaging in the diagnosis of liver metastases from colorectal carcinomas Reviewed
T Furuhata, K Okita, T Tsuruma, F Hata, Y Kimura, T Katsuramaki, M Mukaiya, N Hirokawa, T Ichimura, N Yama, K Koito, K Sasaki, K Hirata
DIGESTIVE SURGERY 20 ( 4 ) 321 - 325 2003
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Brachial plexus: Normal anatomy and pathological conditions Reviewed
Kazusa Hyodoh, Hideki Hyodoh, Hidenari Akiba, Mitsuharu Tamakawa, Noriko Nakamura, Naoya Yama, Takaharu Syonai, Tadashi Tsuchimoto, Hidechika Ohmoto, Masashi Ogasawara, Michio Banda, Makoto Furuse, Masato Hareyama
Current Problems in Diagnostic Radiology 31 ( 5 ) 179 - 188 2002
MISC
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Radiographic Examinations for Severe Sepsis/Septic Shock Patients
36 ( 11 ) 987 - 990 2012.11
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A case of Churg-Strauss syndrome complicated with diffuse alveolar hemorrhage that was treated by plasma exchange
Yoshida Shin-ichiro, Tanabe Miyuki, Masuda Yoshiki, Imaizumi Hitoshi, Yama Naoya, Tatsumi Hiroomi, Goto Kyoko, Asai Yasufumi
Journal of the Japanese Society of Intensive Care Medicine 19 ( 4 ) 623 - 627 2012
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Change of radioactivity of aqueous solution of I-131 with evaporation
( 7 ) 34 - 36 2011.12
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Attenuation of the radiation dose rate in patients treated with I-131
( 6 ) 34 - 36 2010.12
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Management of the radiation dose rate and iodine distribution in patients treated with I-131
( 5 ) 29 - 31 2009.12
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False working of fire alarm due to radiation
( 4 ) 37 - 39 2008.12
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Chest X-ray of aortic injury
The Japanese journal of acute medicine 32 ( 13 ) 1853 - 1856 2008.12
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Thoracic Aortic Stent Grafting as a Life-saving Procedure in an Emergency Medical Center
KURIMOTO Yoshihiko, ASAI Yasufumi, HASE Mamoru, NARA Satoshi, MORI Kazuhisa, YAMA Naoya, ITO Toshiro, BABA Toshio, KAWAHARADA Nobuyoshi, HIGAMI Tetsuya
48 ( 3 ) 283 - 292 2008.6
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Enhanced ultrasonography findings of echinococcossis of the liver
SAITOU Masato, HIROKAWA Naoki, SATOH Taishi, KAWAI Yuriko, KASAHARA Michiko, YAMA Naoya, HAREYAMA Masato, NISHIDA Mutsumi, KOITO Kazumitsu
35 S452 2008.4
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Ultrasound of small pancreatic cancer : comparison with CT and endoscopic ultrasound
HIROKAWA Naoki, SAITO Masato, KOITO Kazumitsu, SATOH Taishi, KAWAI Yuriko, KASAHARA Michiko, YAMA Naoya, HAREYAMA Masato
35 S373 2008.4
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巻頭インタビュー 北海道の地域医療に貢献する 札幌医科大学付属病院院長 塚本泰司先生 放射線医学講座 山直也先生に聞く
塚本 泰司, 山 直也, 寺田
PET journal ( 4 ) 4 - 6 2008
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Imaging of aortic aneurysm
The Japanese journal of acute medicine 31 ( 4 ) 387 - 391 2007.4
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A case of spinal epidural and pelvic abscess with the rectal perforation
Hiroaki Shima, Eiri Ezoe, Osamu Nara, Koji Hashimoto, Reiko Kyan, Masato Isobe, Tomohisa Furuhata, Naoya Yama, Yasufumi Asai, Koichi Hirata
Japanese Journal of Gastroenterological Surgery 40 ( 5 ) 665 - 670 2007
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A case of spinal epidural and pelvic abscess with the rectal perforation
Hiroaki Shima, Eiri Ezoe, Osamu Nara, Koji Hashimoto, Reiko Kyan, Masato Isobe, Tomohisa Furuhata, Naoya Yama, Yasufumi Asai, Koichi Hirata
Japanese Journal of Gastroenterological Surgery 40 ( 5 ) 665 - 670 2007
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Abdominal Emergency Medicine and Information System : Transporting a Patient by Image Transmission Using E-mail from a Remote Area and as Telemedicine Image Transmission Using Digital Cellular Phone from Ambulance
EZOE Eiri, ITOH Yasushi, YAMA Naoya, SHIMA Hiroaki, HIRATA Koichi, ASAI Yasufumi
26 ( 5 ) 611 - 616 2006.7
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EVALUATION OF LIVER FUNCTION PROGNOSIS BY TC-99m-GSA LIVER SCINTIGRAPHY IN SEVERE LIVER DYSFUNCTION WITH LIVER TRAUMA
ISOBE Masato, EZOE Eiri, YAMA Naoya, WADA Takeshi, KURIMOTO Yoshihiko, MASUDA Yoshiki, IMAIZUMI Hitoshi, ASAI Yasuhumi
20 ( 3 ) 272 - 277 2006.7
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A Novel Method for the Detection and the Localization of Intestinal Bleeding Using a Fusion Image of Tc-99m-labeled RBC SPECT and X-ray CT
KIMURA Yasutoshi, YAMA Naoya, ISOBE Masato, NOBUOKA Takayuki, FURUHATA Tomohisa, ASAI Yasufumi, HAREYAMA Masato, HIRATA Koichi
26 ( 3 ) 387 - 389 2006.3
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Abdominal Emergency Medicine and Information System-Transporting a Patient by Image Transmission Using E-mail from a Remote Area and as Telemedicine Image Transmission Using Digital Cellular Phone from Ambulance-
Ezoe Eiri, Itoh Yasushi, Yama Naoya, Shima Hiroaki, Hirata Koichi, Asai Yasufumi
Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine) 26 ( 5 ) 611 - 616 2006
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A Novel Method for the Detection and the Localization of Intestinal Bleeding Using a Fusion Image of Tc-99m-labeled RBC SPECT and X-ray CT
Kimura Yasutoshi, Yama Naoya, Isobe Masato, Nobuoka Takayuki, Furuhata Tomohisa, Asai Yasufumi, Hareyama Masato, Hirata Koichi
Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine) 26 ( 3 ) 387 - 389 2006
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Evaluation of the treatment effect of chemoradiation for advanced pancreatic cancer with enhanced ultrasonography
SATOH Taishi, KOITO Kazumitsu, NISHIDA Mustumi, HIROKAWA Naoki, KAWAAI Yuriko, SOMEYA Masanori, SHOUNAI Takaharu, YAMA Naoya, HYOUDOU Hideki
32 2005.4
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Diagnositic ability of Contrast Enhanced Ultrasound with DD-723 in liver tumors
NISHIDA Mutsumi, KOITO Kazumitsu, HIROKAWA Naoki, SATOH Taishi, KAWAI Yuriko, SOMEYA Masanori, SHONAI Takaharu, YAMA Naoya, HYODOH Hideki, HAREYAMA Masato
32 2005.4
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Evaluation of Local Tumor Control, Survival rate and Apoptosis of Rat Liver Cancer sonicated by High Intensity Focused Ultrasound
HIROKAWA Naoki, KOITO Kazumitsu, NISHIDA Mutsumi, SATOH Taishi, KAWAI Yuriko, SOMEYA Masanori, SYONAI Takaharu, YAMA Naoya, HYODO Hideki, KUDO Nobuki, YAMAMOTO Katsuyuki, HAREYAMA Masato
32 2005.4
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Evaluation of the treatment effect of chemoradiation for advanced pancreatic cancer with enhanced ultrasonography
SATOH Taishi, KOITO Kazumitsu, NISHIDA Mustumi, HIROKAWA Naoki, KAWAAI Yuriko, SOMEYA Masanori, SHOUNAI Takaharu, YAMA Naoya, HYOUDOU Hideki
32 2005.4
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Diagnositic ability of Contrast Enhanced Ultrasound with DD-723 in liver tumors
NISHIDA Mutsumi, KOITO Kazumitsu, HIROKAWA Naoki, SATOH Taishi, KAWAI Yuriko, SOMEYA Masanori, SHONAI Takaharu, YAMA Naoya, HYODOH Hideki, HAREYAMA Masato
32 2005.4
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Evaluation of Local Tumor Control, Survival rate and Apoptosis of Rat Liver Cancer sonicated by High Intensity Focused Ultrasound
HIROKAWA Naoki, KOITO Kazumitsu, NISHIDA Mutsumi, SATOH Taishi, KAWAI Yuriko, SOMEYA Masanori, SYONAI Takaharu, YAMA Naoya, HYODO Hideki, KUDO Nobuki, YAMAMOTO Katsuyuki, HAREYAMA Masato
32 2005.4
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New Approach to Detecting Cervical Lymph Node Metastasis Using Contrast-Enhanced Ultrasound : Micro Flow Imaging with Levovist^【○!R】
NISHIDA Mutsumi, KOITO Kazumitsu, ICHIMURA Takeshi, HIROKAWA Naoki, KAWAI Yuriko, SOMEYA Masanori, SYONAI Takaharu, NAKATA Kensei, YAMA Naoya, KAMIYAMA Naohisa
31 ( 5 ) J347 - J353 2004.9
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New approach to the detection of Cervical Lymph Node metastasis by contrast enhanced Ultrasound : Micro Flow Imaging applied for Levovist
NISHIDA Mutsumi, KOITO Kazumitsu, ICHIMURA Takeshi, HIROKAWA Naoki, KAWAI Yuriko, SOMEYA Masanori, SYONAI Takaharu, NAKATA Kensei, YAMA Naoya, HYOUDOU Hideki, HAREYAMA Naoto, NAKAYA Shigemitsu, KAMIYAMA Naoihsa
31 2004.4
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胸部X線,胸部CT,MRI,心臓核医学検査 (特集 胸部外傷--診断・治療の進歩) -- (各種診断法の有用性と限界)
山 直也, 晴山 雅人, 浅井 康文
救急医学 26 ( 12 ) 1684 - 1691 2002.11
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A Case of Hepatocellular Carcinoma : The Feasibility of Intravenous Contrast Enhanced Ultrasonography in Evaluating Percutaneous Microwave Coagulation Therapy
HIROKAWA Naoki, KOITO Kazumitsu, NAKATA Kensei, ICHIMURA Takeshi, SOMEYA Masanori, SHOUNAI Takaharu, YAMA Naoya, HYOUDOU Hideki
29 ( 1 ) J17 - J21 2002.1
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Estimation of ^<99m>Tc-GSA Receptor Amount by Non-Linear 3-Compartment Model : Ligand-Receptor Binding Model without Blood Sampling
FUJIMORI Kenji, SHOUNAI Takaharu, KOITO Kazumitsu, YOSHIDA Satoru, TAKEDA Miki, YAMA Naoya, KATSURAMAKI Tadashi, FURUHATA Tomohisa, HIRATA Kouichi, HAREYAMA Masato
KAKU IGAKU (Jpn J Nucl Med) 36 ( 7 ) 753 - 760 1999.9
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Comparison between High and Low Dose Rate of Intracavitary Irradiation for Carcinoma of The Uterine Cervix
HAREYAMA Masato, OOUCHI Atusi, SIDOU Mituo, TAKEDA Miki, YAMA Naoya, SAKATA Kouichi, MORITA Kazuo
17 ( 1 ) 143 - 143 1995.10
Research Projects
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Evaluation of rectal cancer aggressiveness based on conductivity imaging
Grant number：18K07635 2018.4 - 2023.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Grant amount：\4290000 （ Direct Cost: \3300000 、 Indirect Cost：\990000 ）
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Establishment of early detection and treatment assessment of pulmonary hypertension by PC-cine MRI
Grant number：16K10323 2016.4 - 2019.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Murayamma Sadayuki
Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）
Phase contrast MRI (PC-MRI) can determine pulmonary hemodynamics noninvasively. Pulmonary hypertension causes changes in pulmonary hemodynamics and is a factor for acute exacerbation and death in interstitial lung diseases (ILD). The purpose of this study was to determine the association between pulmonary hemodynamics measured by PC-MRI and episodes of acute exacerbations and death in patients with ILD related pulmonary hypertension. Reduction in right cardiac output, as detected by PC-MRI, was associated with acute exacerbation and increased mortality in ILD. MR examination to detect right ventricular dysfunction is useful for predicting the poor prognosis in fibrotic ILD patients, even if they are not combined with pulmonary hypertension.
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Predicting treatment effect and prognosis by using IVIM
Grant number：26461831 2014.4 - 2017.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Hatakenaka Masmaitsu
Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）
In total, 28 patients with head and neck cancer who were treated with (chemo)radiotherapy were enrolled in the present study. However, 8 patients were excluded due to poor image quality and/or inadequate clinical data. Further, patients with nasopharyngeal cancer were excluded because its D is lower and sensitive to chemoradiotherapy. Finally, 10 patients were statistically analyzed.
The pre-treatment D value for 6 patients without recurrence was 0.640±0.168 mm2/s and that for 4 ones with recurrence was 0.921±0.204 mm2/s and statistically significant difference was observed (p<0.05). The ratio of D value increase at 10Gy was 0.350±0.533 without recurrence and 0.04±0.174 with recurrence but statistical significance was not observed. F(perfusion fraction) and D*(perfusion) derived from IVIM method show wide variation. Signal intensity at b=25 s/mm2 was lower than that at b=50 s/mm2 in some cases. Thus, F and D* were not analyzed. -
Clinical and Basic Researches of Hepatic Stem Cells onLiver Regeneration as Defense Mechanism.
Grant number：22390259 2010 - 2012
Ministry of Education, Culture, Sports, Science and Technology Grants-in-Aid for Scientific Research(基盤研究(B)) 基盤研究(B)
Koichi HIRATA, Toshihiro MITAKA, Toru MIZUGUCHI, Yukio NAKAMURA, Makoto MEGURO, Masaki KAWAMOTO, Naoya YAMA, Hiroomi TATSUMI, Shigenori OTA, Masafumi IMAMURA, Hiroshi YAMAGUCHI, Takashi KOJIMA, Norimasa SAWADA
Authorship：Collaborating Investigator(s) (not designated on Grant-in-Aid) Grant type：Competitive
Grant amount：\19240000 （ Direct Cost: \14800000 、 Indirect Cost：\4440000 ）
We have achieved the results by the clinical and basic studies.【Study 1】We developed a rat model of acute liver failure after 2/3 partial hepatectomy (PH) for non-alcoholic steatohepatitis (NASH)-related cirrhosis. The mechanism by which HT improved the survival of the model rats was examined in short- and long-term investigations. Overall survival was significantly longer in the HT group than the non-HT group (7-day survival rates: 46.7% and 7.7%, respectively). Preoperative HT might improve the survival of rats with NASH-related cirrhosis after PH by preventing the host hepatocytes from accelerating their growth and falling into apoptosis. 【Study 2】We developed software to calculate the pixels of interest in the area between the hepatic and heart curves (ABC) of 99mTc-galactocyl human serum albumin (GSA) scintigraphy. The area under the receiver operating characteristic curve (AUC) was calculated for evaluation of Child-Pugh score grade B (Child B), pathological chronic hepatitis (CH), and liver cirrhosis (LC). We developed a novel liver functional indicator, the ABC, to count radioactivity in sequence.