Details of a Researcher - SASAKI Takeshi

Papers - SASAKI Takeshi

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Association Between Occupational Participation and Quality of Life in Japanese Older Adults

Suguru Shimokihara, Kazuki Yokoyama, Hikaru Ihira, Yuriko Matsuzaki-Kihara, Atsushi Mizumoto, Hideyuki Tashiro, Hidekazu Saito, Keitaro Makino, Kiyotaka Shimada, Kosuke Yama, Ryo Miyajima, Takeshi Sasaki, Nozomu Ikeda

OTJR: Occupational Therapy Journal of Research ( SAGE Publications ) 2025.03

Positive associations between occupational participation and quality of life (QoL) are known in various populations, but there are few reports in older adults in Japan. To quantify the association between occupational participation in meaningful occupations and QoL among Japanese community-dwelling older adults. A self-administered questionnaire was sent to 626 older adults. QoL was assessed using the World Health Organization (WHO)-five well-being index, and occupational participation in meaningful occupations was measured with the self-administered occupational performance index. The association between occupational participation and QoL was analyzed. Among 367 participants, significant associations were found between occupational participation in meaningful occupations and QoL. In addition, participants with lower QoL exhibited lower levels of occupational participation in occupational control, occupational balance, and satisfaction of performance domains. There is a positive association between occupational participation and QoL among Japanese older adults. Occupational therapists should prioritize occupational participation to support the well-being of older adults.

DOI

Association Between the Use of Information and Communication Technology Tools and Each Domain of Cognitive Function Among Community-Dwelling Older Adults: A Prospective Cohort Study

Kazuki Yokoyama, Hikaru Ihira, Suguru Shimokihara, Yuriko Matsuzaki-Kihara, Atsushi Mizumoto, Hideyuki Tashiro, Hidekazu Saito, Keitaro Makino, Shunpei Katsuura, Kiyotaka Shimada, Kosuke Yama, Ryo Miyajima, Takeshi Sasaki, Nozomu Ikeda

Cureus ( Springer Science and Business Media LLC ) 2025.02 [Refereed]

DOI

Effects of Complex Movement on the Excitability of the Ipsilateral Primary Motor Cortex and Spinal Motoneurons Contralateral to the Movement: A Comparison of Ball Rotation and Grasping Tasks with Equivalent Muscle Activity

Rin Kosuge, Takehiro Sukegawa, Mayu Akaiwa, Eriko Shibata, Ryo Kurokawa, Yasushi Sugawara, Satoshi Kudoh, Yuya Matsuda, Hidekazu Saito, Takeshi Sasaki, Kazuhiro Sugawara

Brain Sciences 2025.02

DOI

Linear association between frailty as assessed by the Kihon Checklist and quality of life in community-dwelling older adults: A cross-sectional population-based study

Annals of Geriatric Medicine and Research ( The Korean Geriatrics Society ) 2024.10 [Refereed]

DOI

Development of the Self-Assessment Self-Disclosure Questionnaire to Examine the Association between Self-Disclosure and Frailty among Community-Dwelling Older Adults in Japan

Kazuki Yokoyama, Hikaru Ihira, Yuriko Matsuzaki-Kihara, Atsushi Mizumoto, Hideyuki Tashiro, Kiyotaka Shimada, Kosuke Yama, Ryo Miyajima, Takeshi Sasaki, Naoki Kozuka, Nozomu Ikeda

Geriatrics ( MDPI AG ) 9 ( 3 ) 67 - 67 2024.05 [Refereed]

Self-disclosure is the attitude of communicating one’s experiences and condition to others and is an indicator of mental health and an open personality. Frailty, characterized by reduced physical and psychological resistance, predicts the incidence of dependency and mortality. Although low self-disclosure may be associated with frailty, there is no scale to measure older adults’ self-disclosure. This cross-sectional study assessed the validity of a self-assessment self-disclosure questionnaire and examined the association between the content of self-disclosures to friends and acquaintances and frailty among community-dwelling older adults. A total of 237 adults aged ≥65 in Japan were surveyed using a mailed self-administered questionnaire in 2021. The self-disclosure scale consisted of 10 items and showed adequate validity. Participants were classified into a robust group (n = 117, women 57.3%) and a frailty group (n = 120, women 73.3%) using the Kihon Checklist. After adjusting for covariates, multivariate-adjusted logistic regression models revealed frailty was associated with lower self-disclosure of recent positive events, motivation and strengths (indicating strong points) in life, relationships with family and relatives, experiences of work and social activities, and financial status. The proposed questionnaire must still be further tested in other populations, but our initial results may contribute to preventing frailty and improving mental health among community-dwelling older adults.

DOI

脳卒中後アパシーによる身体活動量の減少が病棟歩行自立時期に及ぼす影響アパシー症例と非アパシー症例の比較による検討

小菅凜, 工藤哲史, 赤岩眞悠, 佐々木健史, 古田亮一, 菅原和広

総合リハビリテーション ( (株)医学書院 ) 52 ( 3 ) 283 - 287 2024.03 [Refereed]

＜文献概要＞脳卒中患者に生じるアパシー(post-stroke apathy:PSA)は,日常生活動作(activities of daily living:ADL)の回復不良に影響する.歩行能力の回復は自宅退院に向けたリハビリテーション目標としてADLのなかでも特に重要である.本報告では脳卒中患者2症例を経時的に追跡し,PSAが病棟歩行自立に及ぼす影響について検討した.対象は病棟歩行自立の時期が約1ヵ月異なる2症例で,1症例目は発症から退院までPSAを認め,2症例目では同期間でPSAを認めなかった.PSA症例は非PSA症例と比較して歩行自立水準に至るまで期間を要した.その要因として,歩行自立時における歩行評価によって下肢筋力低下,運動耐容能低下や歩行量不足が考えられた.PSAによって病棟での身体活動量が減少し,運動耐容能や筋力の低下などの二次合併症の発生による歩行量の増加不良が生じたため,結果的に病棟歩行自立が遅延したことが文献的考察より示唆された.

Does 20 Hz Transcranial Alternating Current Stimulation over the Human Primary Motor Cortex Modulate Beta Rebound Following Voluntary Movement?

Mayu Akaiwa, Yuya Matsuda, Ryo Kurokawa, Yasushi Sugawara, Rin Kosuge, Hidekazu Saito, Eriko Shibata, Takeshi Sasaki, Kazuhiro Sugawara, Naoki Kozuka

Brain sciences 14 ( 1 ) 2024.01 [Refereed] [International journal]

Beta frequency oscillations originating from the primary motor cortex increase in amplitude following the initiation of voluntary movement, a process termed beta rebound. The strength of beta rebound has been reported to predict the recovery of motor function following stroke, suggesting therapeutic applications of beta rebound modulation. The present study examined the effect of 20 Hz transcranial alternating current stimulation (tACS) on the beta rebound induced by self-paced voluntary movement. Electroencephalograms (EEGs) and electromyograms (EMGs) were recorded from 16 healthy adults during voluntary movements performed before and after active or sham tACS. There was no significant change in average beta rebound after active tACS. However, the beta rebound amplitude was significantly enhanced in a subset of participants, and the magnitude of the increase across all participants was negatively correlated with the difference between individual peak beta frequency and tACS frequency. Thus, matching the stimulus frequency of tACS with individual beta frequency may facilitate therapeutic enhancement for motor rehabilitation.

DOI PubMed

Event-Related Brain Potentials N140 and P300 during Somatosensory Go/NoGo Tasks Are Modulated by Movement Preparation.

Yuya Matsuda, Yasushi Sugawara, Mayu Akaiwa, Hidekazu Saito, Eriko Shibata, Takeshi Sasaki, Kazuhiro Sugawara

Brain sciences 14 ( 1 ) 2023.12 [Refereed] [International journal]

The Go/NoGo task requires attention and sensory processing to distinguish a motor action cue or 'Go stimulus' from a 'NoGo stimulus' requiring no action, as well as motor preparation for a rapid Go stimulus response. The neural activity mediating these response phases can be examined non-invasively by measuring specific event-related brain potentials (ERPs) using electroencephalography. However, it is critical to determine how different task conditions, such as the relationship between attention site and movement site, influence ERPs and task performance. In this study, we compared attention-associated ERP components N140 and P300, the performance metrics reaction time (RT) and accuracy (%Error) and movement-related cortical potentials (MRCPs) between Go/NoGo task trials in which attention target and movement site were the same (right index finger movement in response to right index finger stimulation) or different (right index finger movement in response to fifth finger stimulation). In other Count trials, participants kept a running count of target stimuli presented but did not initiate a motor response. The N140 amplitudes at electrode site Cz were significantly larger in Movement trials than in Count trials regardless of the stimulation site-movement site condition. In contrast, the P300 amplitude at Cz was significantly smaller in Movement trials than in Count trials. The temporal windows of N140 and P300 overlapped with the MRCP. This superposition may influence N140 and P300 through summation, possibly independent of changes in attentional allocation.

DOI PubMed

Effects of repetitive practice of motor tasks on somatosensory gating.

Mayu Akaiwa, Yuya Matsuda, Hidekazu Saito, Eriko Shibata, Takeshi Sasaki, Kazuhiro Sugawara

Frontiers in human neuroscience 17 1131986 - 1131986 2023 [Refereed] [International journal]

INTRODUCTION: During voluntary muscle contraction, the amplitude of the somatosensory evoked potential (SEP) is reduced by inhibiting sensory information from a peripheral nerve supplying the contracted muscle. This phenomenon is called "gating." We reported that participants with good motor skills indicated strong suppression of somatosensory information. The present study investigated the effects of motor performance improvement following repetitive practice on the SEP amplitude. METHODS: The ball rotation task (BR task) was practiced by 15 healthy participants repetitively. SEPs were recorded before (pre) and after (post) repetitive practice. RESULTS: The BR task performance was significantly improved and the required muscle activation to perform the task was significantly reduced after the repetitive practice. The degree of gating was not significant between pre and post- for the SEP amplitude. A significant correlation was found between changes in SEP amplitude from pre to post and performance improvement. DISCUSSION: After repetitive practice, the degree of gating did not change, but the performance of the BR task improved, and the muscle activity required for the BR task decreased. These results suggest that repetitive practice does not change the degree of gating but changes the mechanism of gating. Furthermore, they indicate that suppression of the somatosensory area may play a role in improving task performance.

DOI PubMed

Movement of the stimulated finger in a Go/NoGo task enhances attention directed to that finger as evidenced by P300 amplitude modulation.

Kazuhiro Sugawara, Mayu Akaiwa, Yuya Matsuda, Eriko Shibata, Hidekazu Saito, Takeshi Sasaki

Frontiers in human neuroscience 17 1178509 - 1178509 2023 [Refereed] [International journal]

Somatosensory cues and the optimal allocation of attentional resources are critical for motor performance, but it is uncertain how movement of a body part modulates directed attention and the processing of somatosensory signals originating from that same body part. The current study measured motor reaction time (RT) and the P300 event-related potential during a required movement response to stimulation of the same body part in a Go/NoGo task under multiple response. In the Movement Condition, participants were instructed to extend their right index finger in response to mild electrical stimulation of the same finger (Go signal) or remain still when receiving electrical stimulation to the fifth right finger (NoGo signal). Movement RTs and P300 amplitudes and latencies were measured under varying Go signal 50% probabilities. In other trial blocks, participants were required to count Go signals but not respond with movement or to ignore all signals while engaged in an unrelated task. Mean RT in the Movement Condition was 234.5 ms. P300 response amplitudes at midline electrodes (Fz, Cz, Pz) were the largest in the Movement Condition. The P300 amplitude at parietal electrode site Pz was significantly greater during Movement Condition trials than during Count Condition trials. The increase in P300 amplitude during trials requiring movement of the same body part receiving somatosensory stimulation suggests that movement itself modulates the attentional resources allocated to that body part.

DOI PubMed

The relationships between motor behavior and sensory gating in the ball rotation task.

Mayu Akaiwa, Yuya Matsuda, Yuta Soma, Eriko Shibata, Hidekazu Saito, Takeshi Sasaki, Kazuhiro Sugawara

Experimental brain research 240 ( 10 ) 2659 - 2666 2022.10 [Refereed] [International journal]

During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the amplitude of the corresponding somatosensory evoked potential (SEP) decreases. This phenomenon is called "gating." The reduction of the SEP amplitude is reportedly significantly larger when task performance is high. However, the relationship between dexterous movement skills and gating remains unclear. In this study, we investigated through a ball rotation (BR) task how dexterous movement skills affect the SEP amplitudes. Thirty healthy subjects performed the BR task comprising the rotation of two wooden balls as quickly as possible. We estimated the median number of ball rotations for each participant and classified the participants into two (fast and slow) groups based on the results. Moreover, we recorded SEPs, while the subjects performed BR tasks or rested. SEP amplitude reduction (P45) was significantly larger in the fast than in the slow group. We also observed that the P45 amplitude during the BR task was attenuated even more so in the case of the participants with better dexterous movement skills. Our results suggest that the participants with better dexterous movement skills might display stronger somatosensory information suppression because of increasing the motor cortex activity and the afferent input during the BR task.

DOI PubMed

Association between Productive Roles and Frailty Factors among Community-Dwelling Older Adults: A Cross-Sectional Analysis.

Kazuki Yokoyama, Hikaru Ihira, Yuriko Matsuzaki-Kihara, Atsushi Mizumoto, Ryo Miyajima, Takeshi Sasaki, Naoki Kozuka, Nozomu Ikeda

International journal of environmental research and public health 19 ( 17 ) 2022.08 [Refereed] [International journal]

The employment rate of older people in Japan is expected to increase in the future owing to the increase in the retirement age. Preventing frailty is imperative to maintaining productive roles of older adults. Therefore, this study aimed to examine the association between productive roles and frailty factors among community-dwelling older adults. A total of 135 older adults, enrolled in 2017, participated in the study. Productive roles and domains related to frailty were measured. We measured usual gait speed and grip strength for the physical domain; Mini-Mental State Examination (MMSE) and Geriatric Depression Scale (GDS-15) scores for the cognitive and mental domains; and social role and group activity for the social domain. Multivariate-adjusted logistic regression models revealed that having productive roles was associated with faster usual gait speed (odds ratios [OR] = 1.05; 95% confidence interval [CI], 1.01-1.08; p = 0.005) and lower GDS-15 score (OR = 0.79; 95% CI, 0.64-0.97; p = 0.023). These results suggest that health promotion to maintain gait speed and prevent depressive symptoms may contribute to maintaining productivity in community-dwelling older adults.

DOI PubMed

The Effect of Pedaling at Different Cadence on Attentional Resources.

Mayu Akaiwa, Koki Iwata, Hidekazu Saito, Eriko Shibata, Takeshi Sasaki, Kazuhiro Sugawara

Frontiers in human neuroscience 16 819232 - 819232 2022 [Refereed] [International journal]

We investigated the relationship between attentional resources and pedaling cadence using electroencephalography (EEG) to measure P300 amplitudes and latencies. Twenty-five healthy volunteers performed the oddball task while pedaling on a stationary bike or relaxing (i.e., no pedaling). We set them four conditions, namely, (1) performing only the oddball task (i.e., control), (2) performing the oddball task while pedaling at optimal cadence (i.e., optimal), (3) performing the oddball task while pedaling faster than optimal cadence (i.e., fast), and (4) performing the oddball task while pedaling slower than optimal cadence (i.e., slow). P300 amplitudes at Cz and Pz electrodes under optimal, fast, and slow conditions were significantly lower than those under control conditions. P300 amplitudes at Pz under fast and slow conditions were significantly lower than those under the optimal condition. No significant changes in P300 latency at any electrode were observed under any condition. Our findings revealed that pedaling at non-optimal cadence results in less attention being paid to external stimuli compared with pedaling at optimal cadence.

DOI PubMed

Altered somatosensory evoked potentials associated with improved reaction time in a simple sensorimotor response task following repetitive practice.

Mayu Akaiwa, Koki Iwata, Hidekazu Saito, Takeshi Sasaki, Kazuhiro Sugawara

Brain and behavior 10 ( 8 ) e01624 2020.08 [Refereed] [International journal]

INTRODUCTION: Repetitive practice of sensorimotor tasks is widely used for neurorehabilitation; however, it is unknown how practice alters sensory processing (e.g., recognition, discrimination, and attentional allocation) and associated cognitive processing, such as decision-making. The purpose of this study was to investigate whether long-latency somatosensory evoked potentials (SEPs) reflecting sensory processing, attention, and decision-making are altered by sensorimotor learning. METHODS: Fifteen participants performed a simple sensorimotor response task (thumb opposition in response to surface electrical stimulation), with experimental recording sessions before and after three days of practice. We then compared multiple SEP waveforms and reaction times (RTs) between pre- and postpractice trials. RESULTS: The RT was reduced after practice of three days, and we found a significant positive correlation between ΔRT and ΔN140lat at F3, Cz, and C3', ΔRT and ΔN250lat at F3, and there was a significant negative correlation between ΔRT and ΔP300amp at C3'. CONCLUSION: The present study suggests that motor learning improves somatosensory processing and attentional allocation via neuroplasticity and that these alterations are reflected by specific SEP changes.

DOI PubMed

Structural analysis of impact of physical, cognitive and social status on the incidence of disability in community-dwelling people aged ≥75 years.

Keitaro Makino, Hikaru Ihira, Atsushi Mizumoto, Kotaro Shimizu, Toyoaki Ishida, Ryo Yamaguchi, Yuriko Kihara, Kazunari Ito, Takeshi Sasaki, Taketo Furuna

Geriatrics & gerontology international 18 ( 12 ) 1614 - 1619 2018.12 [Refereed] [Domestic journal]

AIM: The present study aimed to propose a structural model to explain the interaction of physical, cognitive and social domains of health status in the incidence of disability in community-dwelling people aged ≥75 years. METHODS: We analyzed 185 older adults (mean age 79.4 years, 58.4% female) who participated in a baseline assessment from 2012 to 2013. They were followed for incident certification of care needs in the national long-term care insurance certification system during the 2 years. Baseline assessments included several measurements related to the physical, cognitive and social domains of health status. We compared the model fit index between two hypothesis models - the parallel model and the hierarchical model - using structural equation modeling. RESULTS: During the follow-up period, 15 participants (8.1%) were newly certified as requiring personal support from the long-term care insurance system. The structural equation modeling showed that the hierarchical model, indicating that cognitive and social status were indirectly associated with disability through physical status, had a better fit with the data than the parallel model, indicating that physical, cognitive and social status each were directly associated with disability. CONCLUSIONS: The present results suggest that cognitive and social status might indirectly affect disability incidence through physical aging. Further research is required to examine the temporal relationship between physical, cognitive and social change using data over several time-periods. Geriatr Gerontol Int 2018; 18: 1614-1619.

DOI PubMed

Study of factors as motor function, sensory function, and degree of activity affecting calcaneus bone mineral density in ambulatory hemiplegic patients

森大河, 松田直樹, 稲田亨, 佐々木健史, 古名丈人, 小塚直樹

札幌保健科学雑誌 ( 札幌医科大学 ) 5 ( 5 ) 69 - 76 2016 [Refereed]

本研究では日常的に屋内歩行を行っている脳卒中片麻痺者の麻痺側・非麻痺側の骨密度を計測し、その差と身体・感覚・生活機能に関わる評価項目（運動機能、感覚機能、日常生活活動量）と比較し、骨密度減少との関連性を調査した。対象者は、本研究に同意が得られた27名（男性17名、女性10名）とした。なお、認知症が重度のもの、脳卒中発症後の下肢骨折の既往があるもの、ステロイド系薬剤を使用しているものは除外した。骨評価値減少率平均4.63％であり、骨評価値減少率は発症後経過月数と有意な正の相関が認められた。脳卒中発症後片麻痺を呈したが屋内歩行が可能な高齢者の骨密度や日常生活活動度を含む評価をした結果、経過が長期になるにつれて麻痺側の種骨骨密度が低下し、特に低下がみられる群においては1日の歩数が少なく、運動強度の低い活動の時間が多かった。特に、男性においては中等度以上の活動時間が短いと骨密度の低下につながることがわかった。

DOI CiNii

傾斜外乱時におけるラット動的姿勢調節の特徴

佐々木健史, 長峯隆, 小塚直樹, 松山清治

理学療法科学 ( (一社)理学療法科学学会 ) 30 ( 1 ) 21 - 27 2015.02 [Refereed]

[目的]傾斜外乱時におけるラットの動的姿勢調節の特徴抽出を目的とした。[対象]成ラット5匹。[方法]小動物用重心動揺計を用いて、ラットを側方および前後方向へ異なる傾斜速度で30°までの傾斜外乱を与えた際の重心移動の測定と姿勢変化の動画記録を行った。[結果]側方傾斜では傾斜速度10°/secまでの増加に追随して動的な姿勢変化とそれに伴う特徴的重心移動がみられた。一方、前後方向傾斜では傾斜角度の増加に伴う重心移動はみられたが、顕著な姿勢変化は示さなかった。[結語]側方傾斜では動的姿勢調節による姿勢の補正がなされるが、前後方向傾斜では顕著な姿勢変化を示さず姿勢の安定化が図られているものと示唆された。(著者抄録)

新たな小動物用重心動揺計の試作とその機器特性に関する検討剛体および生体を用いた評価

佐々木健史, 小塚直樹, 長峯隆, 松山清治

札幌保健科学雑誌 ( 札幌医科大学保健医療学部 ) 2 ( 2 ) 45 - 55 2013.03 [Refereed]

International Medical Exchange Program with Jiamusi University of China

小塚直樹, 佐々木健史, 後藤葉子, 乾公美

札幌医科大学保健医療学紀要 ( 札幌医科大学保健医療学部 ) 13 ( 13 ) 113 - 115 2011 [Refereed]

札幌医科大学では、北海道と気候風土の似通った地域にある海外各国の大学と協定を締結し、積極的に学術交流を進めている。1977年にフィンランドの大学との医学交流協定を締結して以降、カナダ、中国、アメリカの諸大学とも同様の交流提携を締結し、研究者の相互派遣など、各種の交流活動を進めてきたが、2008年には中国、佳木斯大学との交流協定を締結した。本報告は、佳木斯大学との交流の実績を紹介すると共に、今後の展望について述べることを目的とする。

DOI CiNii

症例検討会にみるリハビリテーションセラピストの熟達過程

佐々木健史

北海道リハビリテーション学会雑誌 ( 北海道リハビリテーション学会 ) 35 21 - 26 2010.03 [Refereed]

本研究は、リハビリテーションに携わるセラピストが協同で問題解決に取り組む議論の場において、経験年数(熟達度)の違いによる影響や症例検討会の有効性を検証し、熟達過程について考察することを目的に、認知科学の立場から論じた。作業療法士4名(初心者・中堅者・熟達者に設定)による2回のビデオ症例検討会を実施し、発話内容をカテゴリー分類して数を比較した。結果、中堅者の検討会における態度は「思考的な追随」という学習姿勢から、下位への説明や助言を行う「初心者との係り」へと変化し、場の状況によって学習する目的や方法を柔軟に変えていた。症例検討会は「教授的」から「能動的」・「相互依存的」な場に変化したと考えられ、新人教育を効果的に行う上での一つの示唆となる。今後、十分に調整された目的の設定や頻度などが、うまく熟達過程に合わせられることで、リハビリセラピストの熟達化が更に意識的に促進されると考える。(著者抄録)

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Papers - SASAKI Takeshi