Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells 査読

Rena Morita, Satoshi Nishizawa, Toshihiko Torigoe, Akari Takahashi, Yasuaki Tamura, Tomohide Tsukahara, Takayuki Kanaseki, Alice Sokolovskaya, Vitaly Kochin, Toru Kondo, Satoshi Hashino, Masahiro Asaka, Isao Hara, Yoshihiko Hirohashi, Noriyuki Sato

Cancer Science   105 ( 4 )   389 - 395   2014年

High expression of CD109 antigen regulates the phenotype of cancer stem-like cells/cancer-initiating cells in the novel epithelioid sarcoma cell line ESX and is related to poor prognosis of soft tissue sarcoma 査読

Makoto Emori, Tomohide Tsukahara, Masaki Murase, Masanobu Kano, Kenji Murata, Akari Takahashi, Terufumi Kubo, Hiroko Asanuma, Kazuyo Yasuda, Vitaly Kochin, Mitsunori Kaya, Satoshi Nagoya, Jun Nishio, Hiroshi Iwasaki, Tomoko Sonoda, Tadashi Hasegawa, Toshihiko Torigoe, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato

PLoS ONE   8 ( 12 )   e84187   2013年12月

Ectopically Expressed Variant Form of Sperm Mitochondria-Associated Cysteine-Rich Protein Augments Tumorigenicity of the Stem Cell Population of Lung Adenocarcinoma Cells 査読

Akari Takahashi, Yoshihiko Hirohashi, Toshihiko Torigoe, Yasuaki Tamura, Tomohide Tsukahara, Takayuki Kanaseki, Vitaly Kochin, Hiroshi Saijo, Terufumi Kubo, Munehide Nakatsugawa, Hiroko Asanuma, Tadashi Hasegawa, Toru Kondo, Noriyuki Sato

PLOS ONE   8 ( 11 )   e69095   2013年11月

Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal 査読

Yoshitaka Michifuri, Yoshihiko Hirohashi, Toshihiko Torigoe, Akihiro Miyazaki, Jyunki Fujino, Yasuaki Tamura, Tomohide Tsukahara, Takayuki Kanaseki, Junichi Kobayashi, Takanori Sasaki, Akari Takahashi, Kenji Nakamori, Akira Yamaguchi, Hiroyoshi Hiratsuka, Noriyuki Sato

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   439 ( 1 )   96 - 102   2013年9月

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients. 査読

Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K

Cancer science   104 ( 1 )   124 - 129   2013年1月

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes 査読

Akari Takahashi, Toshihiko Torigoe, Yasuaki Tamura, Takayuki Kanaseki, Tomohide Tsukahara, Yasushi Sasaki, Hidekazu Kameshima, Tetsuhiro Tsuruma, Koichi Hirata, Takashi Tokino, Yoshihiko Hirohashi, Noriyuki Sato

CELL STRESS & CHAPERONES   17 ( 6 )   757 - 763   2012年11月

SYT-SSX breakpoint peptide vaccines in patients with synovial sarcoma: A study from the Japanese Musculoskeletal Oncology Group 査読

Satoshi Kawaguchi, Tomohide Tsukahara, Kazunori Ida, Shigeharu Kimura, Masaki Murase, Masanobu Kano, Makoto Emori, Satoshi Nagoya, Mitsunori Kaya, Toshihiko Torigoe, Emiri Ueda, Akari Takahashi, Takeshi Ishii, Shin-ichiro Tatezaki, Junya Toguchida, Hiroyuki Tsuchiya, Toshihisa Osanai, Takashi Sugita, Hideshi Sugiura, Makoto Ieguchi, Koichiro Ihara, Ken-ichiro Hamada, Hiroshi Kakizaki, Takeshi Morii, Taketoshi Yasuda, Taisuke Tanizawa, Akira Ogose, Hiroo Yabe, Toshihiko Yamashita, Noriyuki Sato, Takuro Wada

CANCER SCIENCE   103 ( 9 )   1625 - 1630   2012年9月

NK/T-cell lymphoma of bilateral adrenal glands in a patient with pyothorax 査読

Tomohide Tsukahara, Akira Takasawa, Masaki Murata, Kazuyoshi Okumura, Masato Nakayama, Noriyuki Sato, Tadashi Hasegawa

DIAGNOSTIC PATHOLOGY   7   114   2012年8月

ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells 査読

Junichi Matsuzaki, Toshihiko Torigoe, Yoshihiko Hirohashi, Kenjiro Kamiguchi, Yasuaki Tamura, Tomohide Tsukahara, Terufumi Kubo, Akari Takahashi, Emiri Nakazawa, Eri Saka, Kazuyo Yasuda, Shuji Takahashi, Noriyuki Sato

CARCINOGENESIS   33 ( 5 )   996 - 1003   2012年5月

[Peptide vaccination therapy for bone and soft tissue sarcoma]. 査読

Emori M, Tsukahara T, Kawaguchi S, Wada T

Nihon rinsho. Japanese journal of clinical medicine   69 ( 9 )   1670 - 1673   2011年9月

Autologous CTL response against cancer stem-like cells/cancer-initiating cells of bone malignant fibrous histiocytoma 査読

Masanobu Kano, Tomohide Tsukahara, Makoto Emori, Masaki Murase, Toshihiko Torigoe, Satoshi Kawaguchi, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato

CANCER SCIENCE   102 ( 8 )   1443 - 1447   2011年8月

Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients 査読

Hidekazu Kameshima, Tetsuhiro Tsuruma, Toshihiko Torigoe, Akari Takahashi, Yoshihiko Hirohashi, Yasuaki Tamura, Tomohide Tsukahara, Shingo Ichimiya, Takayuki Kanaseki, Yuji Iwayama, Noriyuki Sato, Koichi Hirata

CANCER SCIENCE   102 ( 6 )   1181 - 1187   2011年6月

Prognostic Significance of HLA Class I Expression in Ewing's Sarcoma Family of Tumors 査読

Hiroki Yabe, Tomohide Tsukahara, Satoshi Kawaguchi, Takuro Wada, Toshihiko Torigoe, Noriyuki Sato, Chihiro Terai, Masaya Aoki, Shigemichi Hirose, Hideo Morioka, Hiroo Yabe

JOURNAL OF SURGICAL ONCOLOGY   103 ( 5 )   380 - 385   2011年4月

HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor 査読

Tomohide Tsukahara, Satoshi Kawaguchi, Toshihiko Torigoe, Akari Takahashi, Masaki Murase, Masanobu Kano, Takuro Wada, Mitsunori Kaya, Satoshi Nagoya, Toshihiko Yamashita, Noriyuki Sato

JOURNAL OF TRANSLATIONAL MEDICINE   7   44   2009年6月

Molecular pathological approaches to human tumor immunology 査読

Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Tomoki Kikuchi, Hiroeki Sahara, Kenjiro Kamiguchi, Shingo Ichimiya, Yasuaki Tamura, Toshihiko Torigoe

PATHOLOGY INTERNATIONAL   59 ( 4 )   205 - 217   2009年4月

Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma 査読

Tomohide Tsukahara, Shigeharu Kimura, Shingo Ichimiya, Toshihiko Torigoe, Satoshi Kawaguchi, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato

CANCER SCIENCE   100 ( 1 )   47 - 53   2009年1月

Clonal T-Cell response against autologous pleomorphic malignant fibrous histiocytoma antigen presented by retrieved HLA-A*0206 査読

Shigeharu Kimura, Yuriko Kozakai, Satoshi Kawaguchi, Tomohide Tsukahara, Kazunori Ida, Masaki Murase, Tadaki Matsumura, Mitunori Kaya, Toshihiko Torigoe, Takuro Wada, Noriyuki Sato, Toshihiko Yamashita

JOURNAL OF ORTHOPAEDIC RESEARCH   26 ( 2 )   271 - 278   2008年2月

Prognostic impact and immunogenicity of a novel osteosarcoma antigen, papillomavirus binding factor, in patients with osteosarcoma 査読

Tomohide Tsukahara, Satoshi Kawaguchi, Toshihiko Torigoe, Shigeharu Kimura, Masaki Murase, Shingo Ichimiya, Takuro Wada, Mitsunori Kaya, Satoshi Nagoya, Takeshi Ishii, Shin-ichiro Tatezaki, Toshihiko Yamashita, Noriyuki Sato

CANCER SCIENCE   99 ( 2 )   368 - 375   2008年2月

Overexpression of papillomavirus binding factor in Ewing's sarcoma family of tumors conferring poor prognosis 査読

Hiroki Yabe, Tomohide Tsukahara, Satoshi Kawaguchi, Takuro Wada, Noriyuki Sato, Hideo Morioka, Hiroo Yabe

ONCOLOGY REPORTS   19 ( 1 )   129 - 134   2008年1月

Identification of CLUAP1 as a human osteosarcoma tumor-associated antigen recognized by the humoral immune system 査読

Hisamitsu Ishikura, Hiroaki Ikeda, Hiroyuki Abe, Takayuki Ohkuri, Hiroaki Hiraga, Kazuo Isu, Tomohide Tsukahara, Noriyuki Sato, Hidemitsu Kitamura, Norimasa Iwasaki, Naoki Takeda, Akio Minami, Takashi Nishimura

INTERNATIONAL JOURNAL OF ONCOLOGY   30 ( 2 )   461 - 467   2007年2月

Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5 査読

Tomohide Tsukahara, Satoshi Kawaguchi, Toshihiko Torigoe, Hiroko Asanuma, Emiri Nakazawa, Kumiko Shimozawa, Yuki Nabeta, Shigeharu Kimura, Mitsunori Kaya, Satoshi Nagoya, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato

CANCER SCIENCE   97 ( 12 )   1374 - 1380   2006年12月

HLA-restricted specific tumor cytolysis by autologous T-lymphocytes infiltrating metastatic bone malignant fibrous histiocytoma of lymph node 査読

T Tsukahara, S Kawaguchi, K Ida, S Kimura, Y Tamura, T Ikeda, T Torigoe, S Nagoya, T Wada, N Sato, TS Yamashita

JOURNAL OF ORTHOPAEDIC RESEARCH   24 ( 1 )   94 - 101   2006年1月

A quest for therapeutic antigens in bone and soft tissue sarcoma 査読

S Kawaguchi, T Wada, T Tsukahara, K Ida, T Torigoe, N Sato, T Yamashita

JOURNAL OF TRANSLATIONAL MEDICINE   3   31   2005年8月

Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer 査読

H Hariu, Y Hirohashi, T Torigoe, H Asanuma, M Hariu, Y Tamura, K Aketa, C Nabeta, K Nakanishi, K Kamiguchi, Y Mano, H Kitamura, J Kobayashi, T Tsukahara, N Shijubo, N Sato

CLINICAL CANCER RESEARCH   11 ( 3 )   1000 - 1009   2005年2月

Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma 査読

S Kawaguchi, T Wada, K Ida, Y Sato, S Nagoya, T Tsukahara, S Kimura, H Sahara, H Ikeda, K Shimozawa, H Asanuma, T Torigoe, H Hiraga, T Ishii, S Tatezaki, N Sato, T Yamashita

JOURNAL OF TRANSLATIONAL MEDICINE   3   1 - 9   2005年1月

Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor 査読

T Tsukahara, Y Nabeta, S Kawaguchi, H Ikeda, Y Sato, K Shimozawa, K Ida, H Asanuma, Y Hirohashi, T Torigoe, H Hiraga, S Nagoya, T Wada, T Yamashita, N Sato

CANCER RESEARCH   64 ( 15 )   5442 - 5448   2004年8月

Crisscross CTL induction by SYT-SSX junction peptide and its HLA-A*2402 anchor substitute 査読

K Ida, S Kawaguchi, Y Sato, T Tsukahara, Y Nabeta, H Sahara, H Ikeda, T Torigoe, S Ichimiya, K Kamiguchi, T Wada, S Nagoya, H Hiraga, A Kawai, T Ishii, N Araki, A Myoui, S Matsumoto, T Ozaki, H Yoshikawa, T Yamashita, N Sato

JOURNAL OF IMMUNOLOGY   173 ( 2 )   1436 - 1443   2004年7月

Simultaneous radial closing wedge and ulnar shortening osteotomies for distal radius malunion 査読

T Wada, S Isogai, K Kanaya, T Tsukahara, T Yamashita

JOURNAL OF HAND SURGERY-AMERICAN VOLUME   29A ( 2 )   264 - 272   2004年3月

Recognition by cellular and humoral autologous immunity in a human osteosarcoma cell line 査読

Yuki Nabeta, Satoshi Kawaguchi, Hiroeki Sahara, Hideyuki Ikeda, Yoshihiko Hirohashi, Takahiro Goroku, Yuriko Sato, Tomohide Tsukahara, Toshihiko Torigoe, Takuro Wada, Mitsunori Kaya, Hiroaki Hiraga, Kazuo Isu, Shinya Yamawaki, Seiichi Ishii, Toshihiko Yamashita, Noriyuki Sato

Journal of Orthopaedic Science   8 ( 4 )   554 - 559   2003年

Improved generation of HLA class I/peptide tetramers 査読

Y Sato, H Sahara, T Tsukahara, M Kondo, Y Hirohashi, Y Nabeta, S Kawaguchi, H Ikeda, T Torigoe, S Ichimiya, Y Tamura, T Wada, T Yamashita, M Goto, H Takasu, N Sato

JOURNAL OF IMMUNOLOGICAL METHODS   271 ( 1-2 )   177 - 184   2002年12月

Detection and induction of CTLs specific for SYT-SSX-derived peptides in HLA-A24(+) patients with synovial sarcoma 査読

Y Sato, Y Nabeta, T Tsukahara, Y Hirohashi, R Syunsui, A Maeda, H Sahara, H Ikeda, T Torigoe, S Ichimiya, T Wada, T Yamashita, H Hiraga, A Kawai, T Ishii, N Araki, A Myoui, S Matsumoto, T Umeda, S Ishii, S Kawaguchi, N Sato

JOURNAL OF IMMUNOLOGY   169 ( 3 )   1611 - 1618   2002年8月

手根管症候群における母指球部の知覚評価

和田 卓郎, 磯貝 哲, 塚原 智英, 石井 清一, 青木 光広

日本手の外科学会雑誌 = The Journal of Japanese Society for Surgery of the Hand   18 ( 5 )   721 - 723   2002年2月

前骨間神経麻痺の自然経過と長期予後

塚原 智英, 和田 卓郎, 北村 三穂, 青木 光広, 石井 清一

日本手の外科学会雑誌 = The Journal of Japanese Society for Surgery of the Hand   17 ( 4 )   411 - 413   2000年12月

肩関節 antero-superior corner 損傷による前(上)方不安定症の1例

福島 直, 岡村 健司, 木村 明彦, 塚原 智英

関節鏡 = ARTHROSCOPY Society magazine guidance & Contribution rules   22 ( 3 )   1997年11月