HIMURO Nobuaki

写真a

Affiliation

School of Medicine, Department of Public Health

Job title

Associate Professor
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Education 【 display / non-display 】

  • 2010
    -
    2013

    Sapporo Medical University   Graduate School of Medicine   博士課程  

  • 2008
    -
    2010

    Sapporo Medical University   Graduate School of Health Sciences   博士課程前期  

  • 1996
    -
    2000

    Sapporo Medical University   School of Health Sciences   Department of Physical Therapy  

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Research Experience 【 display / non-display 】

  • 2022.12
    -
    Now

    Sapporo Medical University   医学部公衆衛生学講座   准教授

  • 2015.04
    -
    2022.11

    Sapporo Medical University   医学部公衆衛生学講座   講師

  • 2013.04
    -
    2015.03

    Sapporo Medical University   医学部公衆衛生学講座   助教

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Research Areas 【 display / non-display 】

  • Life sciences   Healthcare management, medical sociology  

  • Life sciences   Rehabilitation science  

  • Life sciences   Hygiene and public health (non-laboratory)  

  • Life sciences   Hygiene and public health (laboratory)  

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Affiliation 【 display / non-display 】

  • Sapporo Medical University   School of Medicine, Dept.of Public Health   准教授  

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Research Interests 【 display / non-display 】

  • public health

  • epidemiology

  • physical therapy

  • cerebral palsy

  • mobility function

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Papers 【 display / non-display 】

  • Reliability of walking ability measurements in children with cerebral palsy: A mixed-methods study

    Tsugumi Hosokawa Seino, Hisato Nishibu, Nobuaki Himuro, Naoki Kozuka

    Physiotherapy Practice and Research: The Official Journal of The Irish Society of Chartered Physiotherapists ( SAGE Publications )   2025.04  [Refereed]

    Authorship：   Corresponding author

    　View Summary

    Objective This study aimed to compare the reliability of the Timed Up and Go Test (TUG) and 1-Minute Walk Test (1MWT) in children with cerebral palsy (CP); tests were administered by clinically experienced physiotherapists and physiotherapy students. Methods In this mixed-methods study, 30 ambulatory children (mean age: 13 years) with CP were administered TUG and 1MWT by five licensed physiotherapists and 18 physiotherapy students. Results The intraclass correlation coefficient for inter-rater reliability between the physiotherapists and students was 0.99 (95% confidence interval [CI]: 0.98–0.99) for TUG and 0.92 (95% CI: 0.83–0.96) for 1MWT. Α Bland–Altman analysis identified a fixed bias in the negative and positive directions for TUG and 1MWT, respectively. Statistical analysis revealed a proportional bias in TUG. A qualitative analysis showed that while physiotherapists followed the instruction manual and provided clear instructions, the students did not follow the manual and were tense, triggering a negative response from the children. Conclusions The difference in clinical experience of professionals administering the TUG and 1MWT to children with CP impacted measurement outcomes. In contrast to physiotherapy students, more experienced physiotherapists ensured that the child was not anxious, provided clear instructions, and performed measurements as per the manual.

    DOI

  • Current Evidence in Knee-Ankle-Foot Orthosis Therapy for Patients with Stroke: A Systematic Review of Observational Studies

    Eiji Kobayashi, Kenta Hiratsuka, Hirokazu Haruna, Nobue Kojima, Nobuaki Himuro

    JPO Journal of Prosthetics and Orthotics ( Ovid Technologies (Wolters Kluwer Health) )  37 ( 2 ) e38 - e45  2025.04  [Refereed]

    Authorship：   Last author

    　View Summary

    ABSTRACT Introduction Although knee-ankle-foot orthosis (KAFO) therapy is considered effective for improving functional mobility in patients with stroke, the certainty of the evidence remains unclear. Objective The aim of this study was to determine the certainty of evidence of treatment effect of KAFO therapy, the methodological quality, and the current status of KAFO therapy in patients with stroke based on existing research. Methods Data from studies that examined the treatment effect of KAFO on functional mobility or activities of daily living in patients with stroke were searched on seven databases: PubMed, CINAHL, Scopus, CENTRAL, PEDro, WoS, and Igaku Chuo Zassi. The results were reported according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement. The overall status of KAFO therapy was summarized descriptively. The certainty of the evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Methodological quality was assessed using the STROBE statement. Results Three observational studies were included in the analysis, but no random controlled trials (RCTs) were identified. The certainty of the evidence for treatment effect of KAFO therapy in stroke was very low. The included studies did not adequately control potential confounders. The treatment effects of KAFO therapy for different levels of lower-limb paralysis and those on walking ability outcomes remain unclear. Conclusions The lack of RCTs limits the evidence for the treatment effect of KAFO therapy in patients with stroke. This systematic review of observational studies highlights the low certainty of current evidence and identifies key areas for improvement in future research. Clinical Relevance This is the first systematic review of observational studies to elucidate current evidence of the treatment effect of KAFOs in patients with stroke. KAFOs may improve functional mobility and activities of daily living; however, the certainty of the evidence is very low, and high-quality trials are needed to establish the benefits of KAFO therapy for these patients.

    DOI

  • Self-suppressing behavioral patterns and depressive traits exacerbate chronic pain: Psychological trait assessment using the structured association technique method.

    Shin Hashizume, Masako Nakano, Chihiro Ikehata, Nobuaki Himuro, Kanna Nagaishi, Mineko Fujimiya

    PloS one   20 ( 3 ) e0319647  2025  [Refereed]  [International journal]

    　View Summary

    This study investigated the relationship between psychological traits and chronic pain using the Structured Association Technique (SAT) method to evaluate psychological factors associated with chronic pain. The participants included 105 older adults (23 men, 82 women, mean age 80.82 years) who received rehabilitation services. Chronic pain severity was assessed using a numerical rating scale (NRS), and psychological traits were evaluated by SAT. In addition, maternal attachment experiences in childhood were examined. The NRS showed significant positive correlations with the self-suppressing behavioral pattern (S) scale (r =  0.31, p =  0.001), and the depression (D) scale (r =  0.31, p =  0.001). The proportion of participants with high scores on both the S and D scales (SD group) was notably higher in the high NRS group. Logistic regression analysis showed that the SD group had a higher odds ratio (OR =  8.469, p =  0.004) for severe chronic pain, suggesting that SD traits independently contribute to worse pain. In the SD group, the self-denial scale scores were high, and self-denial traits showed a negative correlation with maternal attachment experiences in childhood. This finding indicates that poor maternal attachment may enhance self-denial traits, which in turn indirectly worsen pain through their effects on S and D traits. The results of this study highlight the importance of S and D traits as psychological factors in chronic pain, particularly in Japanese populations, and suggest that assessing self-suppressing behavioral patterns may be beneficial for pain management. However, the cross-cultural validity of the SAT scales requires further investigation. SAT therapy may provide a comprehensive approach to the treatment and prevention of complex conditions influenced by psychological and social factors, including chronic pain.

    DOI PubMed

  • Maternal age and the rising incidence of hypertensive disorders of pregnancy: A comprehensive analysis of national claims data from Japan.

    Naomi Maeda, Masayuki Koyama, Shintaro Takatsuka, Keisuke Oyatani, Nobuaki Himuro, Tasuku Mariya, Yoshika Kuno, Shiro Hinotsu, Tsuyoshi Saito, Hirofumi Ohnishi

    PloS one   20 ( 2 ) e0319177  2025  [Refereed]  [International journal]

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    BACKGROUND: Hypertensive disorders of pregnancy (HDP) significantly increase the risk of developing hypertension and cardiovascular disease (CVD) later in life and are a major cause of maternal mortality. However, little is known about the nationwide, long-term, all-inclusive status of HDP. OBJECTIVE: To estimate the incidence of HDP from 2011 to 2019 in Hokkaido, Japan, with a focus on age groups. METHODS: Using National Database (NDB) insurance medical data, a retrospective analysis was conducted. Due to the absence of direct pregnancy data, birth numbers were used as a surrogate for the number of pregnant women to calculate the incidence of HDP. RESULTS: The average incidence rate of HDP over 9 years was 6.37%. The incidence rate was lowest among women aged 25-29 years, at 5.58% (95% confidence interval [CI]: 5.43-5.73), and increased with age, peaking at 10.58% (95% CI: 10.10-11.09) among women over 40 years. Notably, the incidence rate for women under 20 years of age was 6.70% (95% CI: 5.97-7.51), which was higher than that for women in their 20s. A mean annual increase of 0.25% in age-adjusted incidence was observed during this period, which was statistically significant (R² =  0.87, p <  0.01). CONCLUSION: This study reveals that the risk of developing HDP is associated with both older childbearing and younger pregnancies and follows a J-curve, suggesting that factors other than maternal aging also contribute to the increased incidence of HDP and that further research on risk factors for HDP, which is on the rise worldwide, is urgently needed.

    DOI PubMed

  • Prehospital emergency care family satisfaction scale for care provided by emergency medical technicians: Scale development and validation.

    Junpei Haruna, Shuji Uemura, Nobuyasu Hayasaka, Yukiko Taguchi, Saori Muranaka, Sachi Niiyama, Hirotoshi Inamura, Keigo Sawamoto, Hirotoshi Mizuno, Nobuaki Himuro, Eichi Narimatsu

    Journal of evaluation in clinical practice    2024.07  [Refereed]  [International journal]

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    RATIONALE: To date, family satisfaction with emergency medical technicians (EMTs) has only been reported through narrative statements in subjective evaluations. Although a quantitative assessment of healthcare professional satisfaction is desirable, no specific measures have been devised to assess family satisfaction with the healthcare and care provided by EMTs. AIMS AND OBJECTIVES: This study aimed to develop and validate an EMT care family satisfaction scale to measure patient satisfaction with prehospital emergency care. METHODS: The study population comprised 216 family members (N = 216) of patients who used ambulances between November 2020 and May 2021 in a single region in Japan. Questionnaires were distributed to the participants who provided informed consent. An exploratory factor analysis of construct validity was performed to validate the Family Satisfaction Scale. The Cronbach's alpha was used to validate the internal consistency reliability of the scale. RESULTS: The exploratory factor analysis results revealed a four-factor structure: 'explanation and communication,' 'physical treatment,' 'psychological support,' and 'environment in the ambulance.' The Cronbach's range (0.80-0.93) for the total score for each of these four factors and the overall total score confirmed favorable internal reliability of this study. CONCLUSIONS: The family satisfaction scale developed in this study was constructed and validated to highlight the role of EMTs and needs of the families in the prehospital care settings. Moreover, this scale can be applied in the evaluation and consideration of interventions to improve family satisfaction with EMTs.

    DOI PubMed

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Books and Other Publications 【 display / non-display 】

  • PT・OTのための子どものリハビリテーション評価マニュアル

    楠本泰士( Part： Contributor, 第1章「測定値の読み方と活用」、第5章「医療分野の移動能力測定（FMS）」、「総合的な上肢機能（ABILHAND-Kids）」、第6章「家族を中心としたかかわり（MPOC）」)

    医学書院  2025.04 ISBN: 4260057758

    ASIN

  • Crosslink basic リハビリテーションテキスト 人間発達学

    浅野大喜( Part： Contributor, 第2章各論10「家族関係の発達」)

    メジカルビュー社  2021.11

  • 小児リハ評価ガイド : 統合と解釈を理解するための道しるべ

    楠本泰士, 友利幸之介( Part： Contributor, 第1章「評価尺度の特性 信頼性・妥当性・反応性」, 第2章「MACS 脳性麻痺児の手指操作能力を評価しよう」, 「CFCS 脳性麻痺児・者のコミュニケーション能力を分類しよう」, 「EDACS 脳性麻痺児・者の摂食・嚥下能力を分類しよう」, 「TUG 歩行機能とバランス能力を評価しよう」, 「ABILOCO-Kids 脳性麻痺児の歩行遂行能力を評価しよう」, 「FMS 日常生活の移動能力を評価しよう」, 「MPOC 家族の思いを評価しよう」))

    メジカルビュー社  2019.10 ISBN: 9784758319485

  • イラストでわかる人間発達学

    上杉 雅之( Part： Contributor, 第3章「発達検査」)

    医歯薬出版  2015.09 ISBN: 4263219457

    ASIN

  • いのちはどう生まれ、育つのか――医療、福祉、文化と子ども (岩波ジュニア新書)

    道信 良子( Part： Contributor, 「優貴にとって「動く」ということ」)

    岩波書店  2015.03 ISBN: 4005007996

    ASIN

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Misc 【 display / non-display 】

  • 健康と幸福を測定する評価尺度

    樋室 伸顕, 阿部 広和, 井上 孝仁

    小児理学療法学 ( (一社)日本小児理学療法学会 )  2 ( Suppl.1 ) 21 - 22  2024.03

  • 脳性麻痺児における介助のしやすさに関連する因子の特定 システマティックレビュー

    井上 孝仁, 和泉 裕斗, 樋室 伸顕, 西部 寿人, 井上 和広, 藤坂 広幸, 大西 浩文

    小児理学療法学 ( (一社)日本小児理学療法学会 )  2 ( Suppl.1 ) 122 - 122  2024.03

  • 脂肪肝指数(FLI)と高血圧発症との関連:日本人における大規模データベースを用いた過去起点コホート研究

    親谷佳佑, 親谷佳佑, 小山雅之, 小山雅之, 中田圭, 中田圭, 樋室伸顕, 古橋眞人, 岡山明, 大西浩文, 大西浩文

    日本疫学会学術総会講演集(Web)   34th  2024

    J-GLOBAL

  • (救急救命士の教育)救急救命士に必要な教育とは 救急隊の活動に対する患者満足度調査の開発

    春名 純平, 早坂 庸靖, 田口 裕紀子, 村中 沙織, 新山 紗千, 稲村 広敏, 上村 修二, 樋室 伸顕, 成松 英智

    救急救命士ジャーナル ( (株)へるす出版 )  3 ( 3 ) 105 - 105  2023.10

  • 北海道の妊娠高血圧症候群の実態調査 NDBを用いた悉皆調査

    前田 尚美, 小山 雅之, 高塚 伸太朗, 親谷 佳佑, 中田 圭, 樋室 伸顕, 大西 浩文

    日本高血圧学会総会プログラム・抄録集 ( (NPO)日本高血圧学会 )  45回   415 - 415  2023.09

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Awards 【 display / non-display 】

  • 奨励賞

    2024.11   第11回日本小児理学療法学会学術大会   脳性麻痺児のリハビリテーションと粗大運動能力の量反応関係：仮想コントロール群を用いたメタアナリシス

    Winner： 樋室伸顕, 西部寿人, 阿部広和, 東周平, 井上孝仁, 楠本泰士, 小山雅之, 大西浩文

  • 優秀演題賞

    2024.11   第11回日本サルコペニア・フレイル学会大会   日本人高齢者において骨格筋量減少は肥満の有無に関わらずインスリン抵抗性進展に寄与する -端野・壮瞥町研究-

    Winner： 世古俊明, 樋室伸顕, 小山雅之, 小川峻一, 赤坂憲, 森満, 大西浩文

  • 奨励賞

    2024.11   第11回日本小児理学療法学会学術大会   脳性麻痺以外の診断・疾患におけるGMFMの適用と評価尺度の特性ーシステマティックレビューー

    Winner： 阿部広和, 東周平, 樋室伸顕

  • 最優秀賞

    2021.12   第8回日本小児理学療法学会学術大会   脳性麻痺児における日本語版Edinburgh Visual Gait Score（観察的歩行評価）の信頼性・妥当性

    Winner： 阿部 広和, 小柳 翔太郎, 楠本 泰士, 樋室 伸顕

  • 最優秀賞

    2021.11   第8回日本予防理学療法学会学術大会   非糖尿病高齢者における下肢筋量がインスリン抵抗性進展に及ぼす影響

    Winner： 世古 俊明, 赤坂 憲, 樋室 伸顕, 小山 雅之, 森 満, 大西 浩文

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Research Projects 【 display / non-display 】

  • 重度脳性麻痺児のリハビリテーションのための評価尺度コアセットの開発

    基盤研究(C)

    Project Year :

    2025.04
    -
    2028.03
     

    樋室 伸顕

  • 小児理学療法研究を推進するための基盤づくり

    基盤研究(C)

    Project Year :

    2021.04
    -
    2024.03
     

    樋室 伸顕

    　View Summary

    日本の小児理学療法の研究は、臨床家と研究者の協働による継続した研究活動が少なく、臨床と研究の結びつきが弱い。そのため日本の小児理学療法における学術的な基盤や指針が存在しない。一方で日本には療育という独自の文化があり、臨床では効果をあげている。これを科学的に定義づけることで、臨床と研究が結びついた日本発の小児理学療法研究の発展へとつながるのではないかと考えた。そこで本研究では、臨床家から臨床上の疑問を集め、それを研究疑問へと構造化する。その疑問の解決のために臨床家とともにシステマティックレビューをおこない、成果はオープンアクセス誌で公表する。同時に新たな研究課題を明確にして公開することで、さらなる研究活動の発展へとつなげる。臨床と研究がつながった小児理学療法研究推進のための基盤をつくることが本研究の目的である。 今年度は、臨床家から募集した臨床上の疑問のうち、4つを研究疑問へと構造化した。そのうち1編は学会発表を終え論文化しており現在投稿準備中である。うち1編はデータベース検索を終え現在1次スクリーニング中、うち1編はPROSPEROへ登録作業中、1編は研究計画書を作成している。

  • 地域一般住民高齢者における重症化予防・介護予防対象ハイリスク者同定の試み

    基盤研究(C)

    Project Year :

    2020.04
    -
    2023.03
     

    大西 浩文, 小山 雅之, 斉藤 重幸, 樋室 伸顕

    　View Summary

    本研究は、我々が継続している地域一般住民コホートにおける高齢者を対象に、高血圧、糖尿病、循環器疾患への罹患とフレイル・サルコペニアの進展の両者に共通する危険因子を明らかにすることを目的としている。令和2年度は平成29年度の受診者で65歳以上の342名を対象とした横断的検討を行い、男女とも下肢筋量体重比(%)とインスリン抵抗性の指標であるHOMA-IRとの間に有意な関連を認めることを確認した。 今年度は縦断的な検討を行うこととし、平成29年度の健診にて65歳以上でフレイル・サルコペニア関連の検査を受けた者のうち初年度の時点で糖尿病の者を除外し、平成30年、令和元年の健診を3年連続受診した206名を対象として、初年度の下肢筋量体重比(%)の男女別中央値で高群、低群の2群に分け、その後のHOMA-IRの変動について、繰り返し測定二元配置分散分析を行ったところ、年齢とともにHOMA-IRは有意に上昇し、下肢筋量体重比(%)が低い群では高い群と比較してHOMA-IRが高く推移することが示された。また、年次と下肢筋量体重比との間には有意な交互作用は認めなかった。また、平成29年受診者中、糖尿病を除外して、令和元年の健診も受診した241名を対象とし、令和元年度の時点でHOMA-IR≧1.73のインスリン抵抗性進展の有無を従属変数とした多重ロジスティック回帰分析を行うと、年齢、性別、腹部肥満の有無で調整後の下肢筋量体重比低下のオッズ比は2.67（95%CI：1.44-4.95）であり、さらに初年度のHOMA-IRで調整してもオッズ比2.17（95%CI：1.07-11.75）であった。以上の結果より、縦断的な検討において、初年度の下肢筋量体重比の低下は、将来のインスリン抵抗性進展の強いリスク因子である可能性が示唆された。

  • A longitudinal study of changes in mobility function in children with cerebral palsy using clinically applicable measurement scales

    Grant-in-Aid for Scientific Research (C)

    Project Year :

    2017.04
    -
    2022.03
     

    Nobuaki Himuro

    　View Summary

    The decline of mobility in persons with cerebral palsy is a limitation to social participation and a risk for disease. Therefore, prevention of mobility decline is an urgent issue in rehabilitation. In this study, we investigated the mobility of persons with cerebral palsy using clinically applicable measurement scales. The Japanese versions of various functional classification systems and gait-related measurement scales related to the mobility abilities of persons with cerebral palsy were developed, and examined their reliability and validity in persons with cerebral palsy in Japan. Furthermore, we showed that it is necessary to combine multiple measurement scales to accurately assess the mobility abilities of persons with cerebral palsy.

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Committee Memberships 【 display / non-display 】

  • 2023.08
    -
    Now

      システマティック・レビュー委員

  • 2021.09
    -
    Now

      評議員

  • 2014.12
    -
    Now

      評議員

  • 　
    -
    2023.10

      システマティック・レビュー支援チーム

  • 　
    -
    2023.08

      文献検索チーム

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