Misc - KAWANISHI Chiaki

精神科における症候・症候群の治療方針，自殺

河西 千秋

臨床精神医学    2006

うつ病の診断と治療

河西 千秋

神奈川県薬剤師会雑誌 薬壷   c  2006

精神科における症候・症候群の治療方針，悪性症候群

河西 千秋

臨床精神医学    2006

精神科卒後研修：講座担当者の立場から

河西 千秋

精神医学    2006

スウェーデン国立自殺予防・精神保健研究センター（NASP）と自殺予防研究マスター・コース．自殺予防と危機介入

河西 千秋

   2006

テーラーメイド治療への薬理遺伝学研究の今後の方向性 (特集1 精神科臨床におけるテーラーメイド治療の可能性を探る)

古野 拓, 河西 千秋, 平安 良雄

精神科 ( 科学評論社 )  7 ( 5 ) 418 - 422  2005.11

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横浜市立大学と関連施設における新しい必修精神科研修への取り組み

佐藤 玲子, 河西 千秋, 塩崎 一昌, 杉山 直也, 藤原 修一郎, 小澤 篤嗣, 小田原 俊成, 平安 良雄

精神神經學雜誌 = Psychiatria et neurologia Japonica ( 日本精神神経学会 )  107 ( 8 ) 841 - 845  2005.08

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Proposal for New Postgraduate Educational Rotation System in Japan

佐藤 玲子, 河西 千秋, 平安 良雄

精神神經學雜誌 = Psychiatria et neurologia Japonica ( 日本精神神経学会 )  107 ( 6 ) 593 - 598  2005.06

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うつ病の薬物療法の原則 (特集 プライマリ・ケアのためのうつ,不安障害の診かた) -- (治療)

加藤 大慈, 河西 千秋, 平安 良雄

治療 ( 南山堂 )  87 ( 3 ) 559 - 566  2005.03

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Succesful treatment of Wernicke encephalopathy in terminally ill cancer patients: Report of 3 cases and review of the literature

Hideki Onishi, Chiaki Kawanishi, Masanari Onose, Tomoki Yamada, Hideyuki Saito, Akira Yoshida, Kazumasa Noda

Supportive Care in Cancer   12 ( 8 ) 604 - 608  2004.08

Book review, literature introduction, etc.  

　View Summary

Although Wernicke encephalopathy has been reported in the oncological literature, only one terminally ill cancer patient with Wernicke encephalopathy has been reported. Wernicke encephalopathy, a potentially reversible condition, may be unrecognized in terminally ill cancer patients. In this communication, we report three terminally ill cancer patients who developed Wernicke encephalopathy. Early recognition and subsequent treatment resulted in successful palliation of delirium. Two of the three patients did not show the classical triad of Wernicke encephalopathy. Common clinical symptoms were delirium and poor nutritional status. Intravenous thiamine administration dramatically improved the symptoms of delirium in all three patients. In terminally ill cancer patients, clinicians must remain aware of the possibility of Wernicke encephalopathy when patients with a poor nutritional status present with unexplained delirium. Early intervention may correct the symptoms and prevent irreversible brain damage and the quality of life for the patient may improve.

PubMed

Transient lesion in the splenium of the corpus callosum, possibly due to carbamazepine [2]

Hiroyuki Narita, Toshinari Odawara, Chiaki Kawanishi, Ikuko Kishida, Eizo Iseki, Kenji Kosaka

Psychiatry and Clinical Neurosciences   57 ( 5 ) 550 - 551  2003.10

Rapid communication, short report, research note, etc. (scientific journal)  

DOI PubMed

Genetic predisposition to neuroleptic malignant syndrome: Implications for antipsychotic therapy

Chiaki Kawanishi

American Journal of PharmacoGenomics   3 ( 2 ) 89 - 95  2003

Book review, literature introduction, etc.  

　View Summary

The pathogenetic mechanism of neuroleptic malignant syndrome (NMS), a potentially lethal adverse effect of antipsychotics, is not well understood. In addition to acquired risk factors, clinical observations suggest a number of genetic factors predisposing patients to NMS. Recent findings in pharmacogenetics indicate that the genetic polymorphisms for drug-metabolizing enzymes, drug transporters, and possibly drug-targeting molecules, are associated with the interindividual differences in drug responses concerning both efficacy and adverse reactions. Genetic association studies have sought to identify polymorphisms influencing susceptibility to NMS, especially with respect to the dopamine D2 receptor, serotonin receptor, and cytochrome P450 2D6. While a few candidate polymorphisms were associated with NMS, a large controlled study is needed to attain statistical power. On the other hand, NMS might include heterogeneous conditions with common characteristic symptoms but different causative mechanisms. Further analysis of individuals with identified genetic mutations or polymorphisms should advance our understanding of mechanisms underlying NMS.

DOI PubMed

塩酸トラゾドン長期投与中に横紋筋融解症を来した1症例--髄液モノアミン所見と薬物代謝能の検討

岸田 郁子, 河西 千秋, 小田原 俊成

精神医学 ( 医学書院 )  44 ( 9 ) 1013 - 1015  2002.09

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長期にわたって精神病様症状を伴いCAG-repeatの延長を認めた若年発症のハンチントン病の一剖検例

金井 晶子, 河西 千秋, 杉山 直也, 小田原 俊成, 井関 栄三, 辰巳 啓二, 小阪 憲司

Neuropathology : official journal the Japanese Society of Neuropathology   17   259 - 259  1997.05

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