YOSHII Shinji

写真a

Affiliation

School of Medicine, Department of Gastroenterology

Job title

Associate Professor
To the head of this page.▲

Research Experience 【 display / non-display 】

  • 2024.09
    -
    Now

    Sapporo Medical University   消化器内科学講座   准教授

  • 2021.02
    -
    2024.08

    札幌医科大学医学部   消化器内科学講座   講師

  • 2019.07
    -
    2021.01

    Sapporo Medical University   School of Medicine   助教

To the head of this page.▲

Professional Memberships 【 display / non-display 】

  • 　
    　
    　

    日本消化管学会

  • 　
    　
    　

    THE JAPANESE SOCIETY OF INTERNAL MEDICINE

  • 　
    　
    　

    The Japanese Society of Gastroenterology

  • 　
    　
    　

    JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY

To the head of this page.▲

Research Areas 【 display / non-display 】

  • Life sciences   Gastroenterology  

To the head of this page.▲

Affiliation 【 display / non-display 】

  • -   消化器内科学講座   Associate Professor  

To the head of this page.▲
 

Research Interests 【 display / non-display 】

  • colorectal neoplasm

  • endoscopy

  • colorectal T1 cancer

  • submucosal invasive cancer

  • colonoscopy

display all >>

To the head of this page.▲

Papers 【 display / non-display 】

  • Hybrid Endoscopic Resection With Endo-knife and Snare for Colorectal Lesions: A Systematic Review and Meta-analysis

    Shinji Yoshii, Takefumi Kikuchi, Yuki Hayashi, Masahiro Nojima, Hiro-o Yamano, Hiroshi Nakase

    Techniques and Innovations in Gastrointestinal Endoscopy ( Elsevier BV )  25 ( 2 ) 135 - 145  2023  [Refereed]

    DOI

  • Efficacy and Safety of Complete Endoscopic Resection of Colorectal Neoplasia Using a Stepwise Endoscopic Protocol with SOUTEN, a Novel Multifunctional Snare.

    Shinji Yoshii, Marina Kubo, Mio Matsumoto, Takefumi Kikuchi, Yasunari Takakuwa

    Clinical endoscopy   53 ( 2 ) 206 - 212  2020.03  [Refereed]  [International journal]

    　View Summary

    BACKGROUND/AIMS: A multifunctional snare SOUTEN has a sharp tip at the top of the snare loop that enables incision of the mucosa, dissection of the submucosal layer, and snaring of lesion. This study assessed the efficacy and safety of complete endoscopic resection of colorectal neoplasia using SOUTEN. METHODS: We analyzed the rates of gross en bloc resection and complete resections of 108 consecutive tumors from 69 patients resected by precutting endoscopic mucosal resection (precutting), hybrid endoscopic submucosal dissection (hybrid), or conventional endoscopic submucosal dissection (conventional) using SOUTEN. RESULTS: Out of the 108 tumors, 50 were resected by precutting, 27 were resected by hybrid after attempting precutting, and the remaining 31 were resected by conventional after attempting precutting and hybrid resections. The median tumor sizes were 14.5 mm for precutting, 16.4 mm for hybrid, and 21.1 mm for conventional. The success rate of gross en bloc resection and histological complete resection were 100% and 94.0% for precutting, 96.4% and 96.4% for hybrid, and 100% and 100% for conventional method, respectively. No procedure-related complication occurred. CONCLUSION: By using SOUTEN, precutting and hybrid were successfully performed on 10-30 mm tumors with a shorter procedure time than conventional without major complications.

    DOI PubMed

  • Validity of endoscopic features for the diagnosis of Helicobacter pylori infection status based on the Kyoto classification of gastritis.

    Yoshii S, Mabe K, Watano K, Ohno M, Matsumoto M, Ono S, Kudo T, Nojima M, Kato M, Sakamoto N

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   32 ( 1 ) 74 - 83  2019.07  [Refereed]  [International journal]

    　View Summary

    OBJECTIVES: Evaluation of Helicobacter pylori infection status (non-infection, past infection, current infection) has become important. This study aimed to determine the usefulness of the Kyoto classification of gastritis for diagnosing H. pylori infection status by endoscopy. METHODS: In this prospective study, 498 subjects were recruited. Seven well-experienced endoscopists blinded to the history of eradication therapy performed the examinations. Endoscopic findings were assessed according to the Kyoto classification of gastritis: diffuse redness, regular arrangement of collecting venules (RAC), fundic gland polyp (FGP), atrophy, xanthoma, hyperplastic polyp, map-like redness, intestinal metaplasia, nodularity, mucosal swelling, white and flat elevated lesion, sticky mucus, depressive erosion, raised erosion, red streak, and enlarged folds. We established prediction models according to a machine learning procedure and compared them with general assessment by endoscopists using the Kyoto classification of gastritis. RESULTS: Significantly higher diagnostic odds were obtained for RAC (32.2), FGP (7.7), and red streak (4.7) in subjects with non-infection, map-like redness (12.9) in subjects with past infection, and diffuse redness (26.8), mucosal swelling (13.3), sticky mucus (10.2) and enlarged fold (8.6) in subjects with current infection. The overall diagnostic accuracy rate was 82.9% with the Kyoto classification of gastritis. The diagnostic accuracy of the prediction model was 88.6% for the model without H. pylori eradication history and 93.4% for the model with eradication history. CONCLUSIONS: The Kyoto classification of gastritis is useful for diagnosing H. pylori infection status based on endoscopic findings. Our prediction model is helpful for novice endoscopists. (UMIN000016674).

    DOI PubMed

  • Factors Associated With Risk for Colorectal Cancer Recurrence After Endoscopic Resection of T1 Tumors

    Shinji Yoshii, Masanori Nojima, Katsuhiko Nosho, Saori Omori, Takaya Kusumi, Hiroyuki Okuda, Hiroyuki Tsukagoshi, Masahiro Fujita, Hiroyuki Yamamoto, Masao Hosokawa

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY ( ELSEVIER SCIENCE INC )  12 ( 2 ) 292 - +  2014.02  [Refereed]  [International journal]

    　View Summary

    BACKGROUND & AIMS: More information is needed on the long-term outcomes of patients who undergo endoscopic resection of colorectal tumors. We evaluated recurrence of colorectal cancer (CRC) after endoscopic resection or a combination of endoscopic research and surgery for T1 colorectal tumors. METHODS: We conducted a retrospective study of 389 patients with T1 CRC treated by endoscopic resection from January 1989 to December 2008 in Sapporo, Japan. We compared outcomes between patients who underwent subsequent surgery (ER + SURG, n = 205) and those who did not (ER only, n = 184) and statistically adjusted baseline differences between the groups according to the propensity scores. RESULTS: There was almost no risk of cancer recurrence among patients without indications for surgery recommended by the Japanese Society for Cancer of the Colon and Rectum (these indications include tumors with vertical margins, deep submucosal invasion, lymphatic or venous invasion, poor differentiation, or high-grade budding). Among patients with indications for surgery, the cumulative risks of recurrence (CRRs) were 3.7% in the ER + SURG group and 20.1% in the ER only group (P = .001). However, the patients with only deep submucosal invasion had a low CRR, even without surgery (2.3% in the ER + SURG group and 3.4% in the ER only groups, P = .867). In contrast, patients with indications for surgery other than deep submucosal invasion (high-risk patients) had much better outcomes when they also underwent surgery (CRRs: 5.8% in the ER + SURG group vs 58.0% in the ER only group, P < .001). CONCLUSIONS: On the basis of a retrospective study of patients who underwent endoscopic resection for T1 CRC, those with tumors with only submucosal invasion are at low risk for cancer recurrence. However, patients with other high-risk tumor features have greater risks for cancer recurrence and benefit from subsequent surgery.

    DOI PubMed

  • A rare case of delayed duodenal perforation due to an over-the-scope clip.

    Yujiro Kawakami, Shinji Yoshii, Masahiro Taniguchi, Yoshiharu Masaki, Taro Sugawara, Yasutoshi Kimura, Hiroshi Nakase

    Endoscopy   56 ( S 01 ) E331-E333  2024.12  [International journal]

    DOI PubMed

display all >>

To the head of this page.▲

Books and Other Publications 【 display / non-display 】

  • これだけは読んでおきたい！ 消化器内視鏡医のための重要論文200篇〈消化管腫瘍編〉

    吉井 新二( Part： Contributor)

    株式会社シービーアール  2018

  • 下部消化管内視鏡スクリーニング検査マニュアル

    吉井 新二( Part： Contributor)

    医学図書出版株式会社  2018

To the head of this page.▲

Misc 【 display / non-display 】

  • 高齢者時代に向けた大腸検査の課題と工夫 腸管洗浄剤服用時に確認すべきリスクとその対策

    亀山 尚弘, 秋田 浩太郎, 一柳 亜貴子, 三宅 高和, 山川 司, 横山 佳浩, 林 優希, 風間 友江, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本大腸検査学会雑誌 ( 日本大腸検査学会 )  40 ( 2 ) 123 - 123  2024.06

  • 当科における大腸ESD後粘膜欠損部に対する内視鏡的手縫い縫合の導入経験

    山川 司, 吉井 新二, 秋田 浩太朗, 三宅 高和, 山野 泰穂, 仲瀬 裕志

    日本大腸肛門病学会雑誌 ( (一社)日本大腸肛門病学会 )  77 ( 5 ) 326 - 326  2024.05

  • 最新技術を用いた消化器診療 内視鏡用軟性持針器を用いた内視鏡的手縫い縫合の臨床導入への取り組み

    山川 司, 吉井 新二, 三宅 高和, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   34 - 34  2024.03

  • 家族性大腸腺腫症患者における胃腫瘍の検討

    佐久間 智也, 山川 司, 室田 文子, 常盤 孝介, 秋田 浩太朗, 一柳 亜貴子, 三宅 高和, 横山 佳浩, 風間 友江, 林 優希, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   64 - 64  2024.03

  • 内視鏡的粘膜下層剥離術後にリンパ節再発をきたした早期胃癌(内視鏡的根治度B)の1例

    秋田 浩太朗, 三宅 高和, 佐久間 智也, 一柳 亜貴子, 山川 司, 横山 佳浩, 風間 友江, 林 優希, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   51 - 51  2024.03

display all >>

To the head of this page.▲

Awards 【 display / non-display 】

  • Best reviewers Award 2023

    2023   Digestive endoscopy  

  • Awards for Outstanding Reviewers

    2020   the Japanese Society of Internal Medicine  

  • Travel grant in IDEN2018

    2018.06   Efficacy of a multifunctional snare (SOUTEN) for precutting endoscopic mucosal resection and endoscopic submucosal dissection.

    Winner： 吉井 新二

  • 第81回大腸癌研究会 優秀発表賞

    2013.07   大腸癌研究会   T1大腸癌に対する内視鏡治療の適応拡大

    Winner： 吉井 新二

  • 平成24年度日本消化器内視鏡学会 学会賞

    2012.10   日本消化器内視鏡学会   大腸SM癌内視鏡的摘除後経過観察例の予後

    Winner： 吉井 新二

To the head of this page.▲
 

Committee Memberships 【 display / non-display 】

  • 2024
    　
    　

      大腸腫瘍に対する内視鏡切除術ガイドライン委員

  • 2023
    -
    Now

      和文誌編集委員会委員

To the head of this page.▲