吉井 新二 (ヨシイ シンジ)

写真a

所属

医学部 消化器内科学講座

職名

准教授

経歴 【 表示 / 非表示

  • 2024年09月
    -
    継続中

    札幌医科大学医学部   消化器内科学講座   准教授

  • 2021年02月
    -
    2024年08月

    札幌医科大学医学部   消化器内科学講座   講師

  • 2019年07月
    -
    2021年01月

    札幌医科大学医学部   消化器内科学講座   助教

所属学協会 【 表示 / 非表示

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    日本消化管学会

  •  
     
     

    日本内科学会

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    日本消化器病学会

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    日本消化器内視鏡学会

研究分野 【 表示 / 非表示

  • ライフサイエンス   消化器内科学  

researchmapの所属 【 表示 / 非表示

  • 札幌医科大学医学部   消化器内科学講座   准教授  

 

研究キーワード 【 表示 / 非表示

  • 大腸腫瘍

  • 内視鏡

  • 大腸T1癌

  • 大腸SM癌

  • 大腸内視鏡

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論文 【 表示 / 非表示

  • Hybrid Endoscopic Resection With Endo-knife and Snare for Colorectal Lesions: A Systematic Review and Meta-analysis

    Shinji Yoshii, Takefumi Kikuchi, Yuki Hayashi, Masahiro Nojima, Hiro-o Yamano, Hiroshi Nakase

    Techniques and Innovations in Gastrointestinal Endoscopy ( Elsevier BV )  25 ( 2 ) 135 - 145  2023年  [査読有り]

    DOI

  • Efficacy and Safety of Complete Endoscopic Resection of Colorectal Neoplasia Using a Stepwise Endoscopic Protocol with SOUTEN, a Novel Multifunctional Snare.

    Shinji Yoshii, Marina Kubo, Mio Matsumoto, Takefumi Kikuchi, Yasunari Takakuwa

    Clinical endoscopy   53 ( 2 ) 206 - 212  2020年03月  [査読有り]  [国際誌]

     概要を見る

    BACKGROUND/AIMS: A multifunctional snare SOUTEN has a sharp tip at the top of the snare loop that enables incision of the mucosa, dissection of the submucosal layer, and snaring of lesion. This study assessed the efficacy and safety of complete endoscopic resection of colorectal neoplasia using SOUTEN. METHODS: We analyzed the rates of gross en bloc resection and complete resections of 108 consecutive tumors from 69 patients resected by precutting endoscopic mucosal resection (precutting), hybrid endoscopic submucosal dissection (hybrid), or conventional endoscopic submucosal dissection (conventional) using SOUTEN. RESULTS: Out of the 108 tumors, 50 were resected by precutting, 27 were resected by hybrid after attempting precutting, and the remaining 31 were resected by conventional after attempting precutting and hybrid resections. The median tumor sizes were 14.5 mm for precutting, 16.4 mm for hybrid, and 21.1 mm for conventional. The success rate of gross en bloc resection and histological complete resection were 100% and 94.0% for precutting, 96.4% and 96.4% for hybrid, and 100% and 100% for conventional method, respectively. No procedure-related complication occurred. CONCLUSION: By using SOUTEN, precutting and hybrid were successfully performed on 10-30 mm tumors with a shorter procedure time than conventional without major complications.

    DOI PubMed

  • Validity of endoscopic features for the diagnosis of Helicobacter pylori infection status based on the Kyoto classification of gastritis.

    Yoshii S, Mabe K, Watano K, Ohno M, Matsumoto M, Ono S, Kudo T, Nojima M, Kato M, Sakamoto N

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   32 ( 1 ) 74 - 83  2019年07月  [査読有り]  [国際誌]

     概要を見る

    OBJECTIVES: Evaluation of Helicobacter pylori infection status (non-infection, past infection, current infection) has become important. This study aimed to determine the usefulness of the Kyoto classification of gastritis for diagnosing H. pylori infection status by endoscopy. METHODS: In this prospective study, 498 subjects were recruited. Seven well-experienced endoscopists blinded to the history of eradication therapy performed the examinations. Endoscopic findings were assessed according to the Kyoto classification of gastritis: diffuse redness, regular arrangement of collecting venules (RAC), fundic gland polyp (FGP), atrophy, xanthoma, hyperplastic polyp, map-like redness, intestinal metaplasia, nodularity, mucosal swelling, white and flat elevated lesion, sticky mucus, depressive erosion, raised erosion, red streak, and enlarged folds. We established prediction models according to a machine learning procedure and compared them with general assessment by endoscopists using the Kyoto classification of gastritis. RESULTS: Significantly higher diagnostic odds were obtained for RAC (32.2), FGP (7.7), and red streak (4.7) in subjects with non-infection, map-like redness (12.9) in subjects with past infection, and diffuse redness (26.8), mucosal swelling (13.3), sticky mucus (10.2) and enlarged fold (8.6) in subjects with current infection. The overall diagnostic accuracy rate was 82.9% with the Kyoto classification of gastritis. The diagnostic accuracy of the prediction model was 88.6% for the model without H. pylori eradication history and 93.4% for the model with eradication history. CONCLUSIONS: The Kyoto classification of gastritis is useful for diagnosing H. pylori infection status based on endoscopic findings. Our prediction model is helpful for novice endoscopists. (UMIN000016674).

    DOI PubMed

  • Factors Associated With Risk for Colorectal Cancer Recurrence After Endoscopic Resection of T1 Tumors

    Shinji Yoshii, Masanori Nojima, Katsuhiko Nosho, Saori Omori, Takaya Kusumi, Hiroyuki Okuda, Hiroyuki Tsukagoshi, Masahiro Fujita, Hiroyuki Yamamoto, Masao Hosokawa

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY ( ELSEVIER SCIENCE INC )  12 ( 2 ) 292 - +  2014年02月  [査読有り]  [国際誌]

     概要を見る

    BACKGROUND & AIMS: More information is needed on the long-term outcomes of patients who undergo endoscopic resection of colorectal tumors. We evaluated recurrence of colorectal cancer (CRC) after endoscopic resection or a combination of endoscopic research and surgery for T1 colorectal tumors. METHODS: We conducted a retrospective study of 389 patients with T1 CRC treated by endoscopic resection from January 1989 to December 2008 in Sapporo, Japan. We compared outcomes between patients who underwent subsequent surgery (ER + SURG, n = 205) and those who did not (ER only, n = 184) and statistically adjusted baseline differences between the groups according to the propensity scores. RESULTS: There was almost no risk of cancer recurrence among patients without indications for surgery recommended by the Japanese Society for Cancer of the Colon and Rectum (these indications include tumors with vertical margins, deep submucosal invasion, lymphatic or venous invasion, poor differentiation, or high-grade budding). Among patients with indications for surgery, the cumulative risks of recurrence (CRRs) were 3.7% in the ER + SURG group and 20.1% in the ER only group (P = .001). However, the patients with only deep submucosal invasion had a low CRR, even without surgery (2.3% in the ER + SURG group and 3.4% in the ER only groups, P = .867). In contrast, patients with indications for surgery other than deep submucosal invasion (high-risk patients) had much better outcomes when they also underwent surgery (CRRs: 5.8% in the ER + SURG group vs 58.0% in the ER only group, P < .001). CONCLUSIONS: On the basis of a retrospective study of patients who underwent endoscopic resection for T1 CRC, those with tumors with only submucosal invasion are at low risk for cancer recurrence. However, patients with other high-risk tumor features have greater risks for cancer recurrence and benefit from subsequent surgery.

    DOI PubMed

  • A rare case of delayed duodenal perforation due to an over-the-scope clip.

    Yujiro Kawakami, Shinji Yoshii, Masahiro Taniguchi, Yoshiharu Masaki, Taro Sugawara, Yasutoshi Kimura, Hiroshi Nakase

    Endoscopy   56 ( S 01 ) E331-E333  2024年12月  [国際誌]

    DOI PubMed

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書籍等出版物 【 表示 / 非表示

  • これだけは読んでおきたい! 消化器内視鏡医のための重要論文200篇〈消化管腫瘍編〉

    吉井 新二( 担当: 分担執筆)

    株式会社シービーアール  2018年

  • 下部消化管内視鏡スクリーニング検査マニュアル

    吉井 新二( 担当: 分担執筆)

    医学図書出版株式会社  2018年

Misc 【 表示 / 非表示

  • 高齢者時代に向けた大腸検査の課題と工夫 腸管洗浄剤服用時に確認すべきリスクとその対策

    亀山 尚弘, 秋田 浩太郎, 一柳 亜貴子, 三宅 高和, 山川 司, 横山 佳浩, 林 優希, 風間 友江, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本大腸検査学会雑誌 ( 日本大腸検査学会 )  40 ( 2 ) 123 - 123  2024年06月

  • 当科における大腸ESD後粘膜欠損部に対する内視鏡的手縫い縫合の導入経験

    山川 司, 吉井 新二, 秋田 浩太朗, 三宅 高和, 山野 泰穂, 仲瀬 裕志

    日本大腸肛門病学会雑誌 ( (一社)日本大腸肛門病学会 )  77 ( 5 ) 326 - 326  2024年05月

  • 最新技術を用いた消化器診療 内視鏡用軟性持針器を用いた内視鏡的手縫い縫合の臨床導入への取り組み

    山川 司, 吉井 新二, 三宅 高和, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   34 - 34  2024年03月

  • 家族性大腸腺腫症患者における胃腫瘍の検討

    佐久間 智也, 山川 司, 室田 文子, 常盤 孝介, 秋田 浩太朗, 一柳 亜貴子, 三宅 高和, 横山 佳浩, 風間 友江, 林 優希, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   64 - 64  2024年03月

  • 内視鏡的粘膜下層剥離術後にリンパ節再発をきたした早期胃癌(内視鏡的根治度B)の1例

    秋田 浩太朗, 三宅 高和, 佐久間 智也, 一柳 亜貴子, 山川 司, 横山 佳浩, 風間 友江, 林 優希, 吉井 新二, 山野 泰穂, 仲瀬 裕志

    日本消化器病学会北海道支部例会・日本消化器内視鏡学会北海道支部例会プログラム・抄録集 ( 日本消化器病学会-北海道支部 )  134回・128回   51 - 51  2024年03月

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受賞 【 表示 / 非表示

  • Best reviewers Award 2023

    2023年   Digestive endoscopy  

  • Awards for Outstanding Reviewers

    2020年   the Japanese Society of Internal Medicine  

  • Travel grant in IDEN2018

    2018年06月   Efficacy of a multifunctional snare (SOUTEN) for precutting endoscopic mucosal resection and endoscopic submucosal dissection.  

    受賞者: 吉井 新二

  • 第81回大腸癌研究会 優秀発表賞

    2013年07月   大腸癌研究会   T1大腸癌に対する内視鏡治療の適応拡大  

    受賞者: 吉井 新二

  • 平成24年度日本消化器内視鏡学会 学会賞

    2012年10月   日本消化器内視鏡学会   大腸SM癌内視鏡的摘除後経過観察例の予後  

    受賞者: 吉井 新二

 

委員歴 【 表示 / 非表示

  • 2024年
     
     

      大腸腫瘍に対する内視鏡切除術ガイドライン委員

  • 2023年
    -
    継続中

      和文誌編集委員会委員