Education 【 display / non-display 】

Education 【 display / non-display 】

• 　

  　

  　

  Gifu University   School of Medicine  

Degree 【 display / non-display 】

Degree 【 display / non-display 】

• 医学博士

Research Experience 【 display / non-display 】

Research Experience 【 display / non-display 】

• 2021.07

  -

  Now

  Sapporo Medical University   Department of Infection Control & Laboratory Medicine   Associate professor

• 2020.05

  -

  2021.06

  Gifu University   Center For Nutrition Support and Infection Control, University Hospital   Associate professor

• 2018.05

  -

  2020.04

  Gifu University   Center For Nutrition Support and Infection Control, University Hospital   Lecturer

• 2012.04

  -

  2018.04

  Gifu University   Department of Urology, University Hospital   Lecturer

• 2006.11

  -

  2012.03

  Gifu University   Department of Urology, University Hospital   併任講師

display all >>

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Life sciences   Urology   感染症学

• Life sciences   Urology  

Affiliation 【 display / non-display 】

Affiliation 【 display / non-display 】

• Sapporo Medical University School of Medicine   Department of Infection Control & Laboratory Medicine   准教授  

Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

• 排尿障害

• 23S rRNA

• 性感染症

• Mycoplasma genitalium

• 最小発育阻止濃度

display all >>

Papers 【 display / non-display 】

Papers 【 display / non-display 】

• Detection of Novel US <i>Neisseria meningitidis</i> Urethritis Clade Subtypes in Japan

  Hideyuki Takahashi, Masatomo Morita, Mitsuru Yasuda, Yuki Ohama, Yoshitomo Kobori, Munekado Kojima, Ken Shimuta, Yukihiro Akeda, Makoto Ohnishi

  Emerging Infectious Diseases ( Centers for Disease Control and Prevention (CDC) )  29 ( 11 )  2023.11

  DOI

• The third nationwide surveillance of antimicrobial susceptibility against Neisseria gonorrhoeae from male urethritis in Japan, 2016-2017.

  Mitsuru Yasuda, Satoshi Takahashi, Jun Miyazaki, Koichiro Wada, Kanao Kobayashi, Masahiro Matsumoto, Hiroshi Hayami, Shingo Yamamoto, Hiroshi Kiyota, Junko Sato, Tetsuya Matsumoto, Hiroshi Yotsuyanagi, Hideaki Hanaki, Naoya Masumori, Yoshiki Hiyama, Hiroyuki Nishiyama, Takahiro Kimura, Hiroki Yamada, Kazumasa Matsumoto, Kiyohito Ishikawa, Yoshikazu Togo, Kazushi Tanaka, Takuya Sadahira, Junichi Inokuchi, Ryoichi Hamasuna, Kenji Ito, Hideo Hirayama, Kenji Hayashi, Yuichiro Kurimura, Hitoshi Kadena, Shin Ito, Yutaka Shiono, Takahiro Maruyama, Masayasu Ito, Koichi Hatano, Hirofumi Chokyu, Hideari Ihara, Satoshi Uno, Koichi Monden, Teruhiko Yokoyama, Motonori Kano, Shinichi Kaji, Motoshi Kawahara, Toru Sumii, Takanori Tojo, Takahide Hosobe, Kazuhiko Naito, Shuichi Kawai, Hirofumi Nishimura, Masanobu Izumitani, Mutsumasa Yoh, Masaru Matsumura, Ryuji Fujita, Kazuo Takayama, Makoto Hara, Shohei Nishi

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   29 ( 11 ) 1011 - 1016  2023.08  [International journal]

  　View Summary

  Neisseria gonorrhoeae is one of the important pathogens of sexually transmitted infections. N. gonorrhoeae is rapidly becoming antimicrobial resistant, and there are few drugs that are effective in the initial treatment of gonorrhea. To understand the trends of antimicrobial susceptibility of N. gonorrhoeae, the Surveillance Committee of the Japanese Society of Infectious Diseases, the Japanese Society for Chemotherapy, and the Japanese Society of Clinical Microbiology conducted the third nationwide antimicrobial susceptibility surveillance of N. gonorrhoeae isolated from male urethritis. The specimens were collected from male patients with urethritis at 30 facilities from May 2016 to July 2017. From the 159 specimens collected, 87 N. gonorrhoeae strains were isolated, and 85 were tested for susceptibility to 21 antimicrobial agents. All strains were non-susceptible to penicillin G. Seven strains (8.2%) were β-lactamase-producing strains. The rates of susceptibility to cefixime and cefpodoxime were 96.5% and 52.9%, respectively. Three strains were non-susceptible with a minimum inhibitory concentration (MIC) of 0.5 mg/L for cefixime. None of the strains were resistant to ceftriaxone or spectinomycin. The susceptibility rate for ciprofloxacin was 23.5% (20 strains), and no strains showed intermediate susceptibility. The susceptibility rate against azithromycin was 81.2%, with one strain isolated with a MIC of 8 mg/L against azithromycin. The results of this surveillance indicate that ceftriaxone and spectinomycin, which are currently recommended for gonococcal infections in Japan, appear to be effective. It will be necessary to further expand the scale of the next surveillance to understand the current status of drug-resistant N. gonorrhoeae in Japan.

  DOI PubMed

• AAUS guideline for chlamydial urethritis.

  Yoshiki Hiyama, Satoshi Takahashi, Mitsuru Yasuda

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   28 ( 2 ) 142 - 145  2022.02  [International journal]

  　View Summary

  Urogenital chlamydial infection is the most common sexually transmitted infection. Many cases of chlamydial infection are reported worldwide every year. Genital chlamydial infection in women can also cause obstetric issues, including infertility and miscarriage. For that purpose, appropriate care should be conducted with the latest knowledge. Only few guidelines come from Asian countries. The Asian Association of Urinary Tract Infection and Sexually Transmitted Infection (AAUS) belonging to the Urological Association of Asia (UAA) had developed the guidelines regarding chlamydial urethritis. We have collected the feedback and updated the guidelines which is now submitted for consideration of publication. In addition to the levels of evidence, the recommendation grades were defined using the modified GRADE methodology. Herein, we present the new edition of the UAA-AAUS guidelines for chlamydial urethritis.

  DOI PubMed

• Nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan: Comparison with the first surveillance report.

  Satoshi Takahashi, Mitsuru Yasuda, Koichiro Wada, Masahiro Matsumoto, Hiroshi Hayami, Kanao Kobayashi, Jun Miyazaki, Hiroshi Kiyota, Tetsuya Matsumoto, Hiroshi Yotsuyanagi, Kazuhiro Tateda, Junko Sato, Hideaki Hanaki, Naoya Masumori, Yoshiki Hiyama, Shin Egawa, Hiroki Yamada, Kazumasa Matsumoto, Kiyohito Ishikawa, Shingo Yamamoto, Yoshikazu Togo, Kazushi Tanaka, Katsumi Shigemura, Shinya Uehara, Hiroyuki Kitano, Keijiro Kiyoshima, Ryoichi Hamasuna, Kenji Ito, Hideo Hirayama, Shuichi Kawai, Yutaka Shiono, Takahiro Maruyama, Shin Ito, Mutsumasa Yoh, Masayasu Ito, Koichi Hatano, Hideari Ihara, Satoshi Uno, Koichi Monden, Teruhiko Yokoyama, Kazuo Takayama, Toru Sumii, Hitoshi Kadena, Motoshi Kawahara, Takahide Hosobe, Masanobu Izumitani, Motonori Kano, Hirofumi Nishimura, Ryuji Fujita, Shinichi Kaji, Kenji Hayashi, Takanori Tojo, Masaru Matumura

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   28 ( 1 ) 1 - 5  2021.09  [International journal]

  　View Summary

  The Urogenital Sub-committee and the Surveillance Committee of the Japanese Society of Chemotherapy, The Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology conducted the second nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis. In this second surveillance study, clinical urethral discharge specimens were collected from patients with urethritis in 26 hospitals and clinics from May 2016 to July 2017. Based on serial cultures, the minimum inhibitory concentration (MIC) could be determined for 41 isolates; the MICs (MIC90) of ciprofloxacin, levofloxacin, tosufloxacin, sitafloxacin, doxycycline, minocycline, erythromycin, clarithromycin, azithromycin and solithromycin were 2 μg/ml (2 μg/ml), 1 μg/ml (0.5 μg/ml), 0.25 μg/ml (0.25 μg/ml), 0.125 μg/ml (0.063 μg/ml), 0.125 μg/ml (0.125 μg/ml), 0.25 μg/ml (0.25 μg/ml), 0.031 μg/ml (0.031 μg/ml), 0.25 μg/ml (0.125 μg/ml), and 0.016 μg/ml (0.008 μg/ml), respectively. In summary, this surveillance project did not identify any strains resistant to fluoroquinolone, tetracycline, or macrolide agents in Japan. In addition, the MIC of solithromycin was favorable and lower than that of other antimicrobial agents. However, the MIC of azithromycin had a slightly higher value than that reported in the first surveillance report, though this might be within the acceptable margin of error. Therefore, the susceptibility of azithromycin, especially, should be monitored henceforth.

  DOI PubMed

• Guidelines for Infection Control in the Urological Field, including Urinary Tract Management (revised second edition).

  Satoshi Takahashi, Soichi Arakawa, Kiyohito Ishikawa, Jun Kamei, Kanao Kobayashi, Katsumi Shigemura, Satoru Takahashi, Yoshiki Hiyama, Ryoichi Hamasuna, Hiroshi Hayami, Satoshi Yazawa, Mitsuru Yasuda, Yoshikazu Togo, Shingo Yamamoto, Koichiro Wada, Toyohiko Watanabe

  International journal of urology : official journal of the Japanese Urological Association   28 ( 12 ) 1198 - 1211  2021.09  [International journal]

  　View Summary

  The Committee for the Development of Guidelines for Infection Control in the Urological Field, including Urinary Tract Management of the Japanese Urological Association, together with its systematic review team and external reviewers, have prepared a set of practice guidelines, an abridged version of which is published herein. These guidelines cover the following topics: (i) foundations of infection control, standard precautions, route-specific precautions, and occupational infection control (including vaccines); (ii) the relationship between urologists and infection control; (iii) infection control in urological wards and outpatient clinics; (iv) response to hepatitis B virus reactivation; (v) infection control in urological procedures and examinations; (vi) prevention of infections occurring in conjunction with medical procedures and examinations; (vii) responses to urinary tract tuberculosis and bacillus Calmette-Guérin; (viii) aseptic handling, cleaning, disinfection, and sterilization of urinary tract endoscopes (principles of endoscope manipulation, endoscope lumen cleaning, and disinfection); (ix) infection control in the operating room (principles of hand washing, preoperative rubbing methods, etc.); (x) prevention of needlestick and blood/bodily fluid exposure and response to accidental exposure; (xi) urinary catheter-associated urinary tract infection and purple urinary bag syndrome; and (xii) urinary catheter-associated urinary tract infections in conjunction with home care. In addressing these topics, the relevant medical literature was searched to the extent possible, and content was prepared for the purpose of providing useful information for clinical practice.

  DOI PubMed

display all >>

Misc 【 display / non-display 】

Misc 【 display / non-display 】

• Association of mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis

  Shin Ichi Maeda, Masayoshi Tamaki, Keitaro Kojima, Takashi Yoshida, Hiroaki Ishiko, Mitsuru Yasuda, Takashi Deguchi, Takashi Deguchi

  Sexually Transmitted Diseases   28   472 - 476  2026

  　View Summary

  Background: Most patients with recurrent symptomatic nongonococcal urethritis receive negative test results for Chlamydia trachomatis and Ureaplasma urealyticum, and the cause of such recurrence usually is unknown. Goal: To assess the association of Mycoplasma genitalium with recurrent nongonococcal urethritis. Study Design: In this study, 72 men with nongonococcal urethritis were treated with levofloxacin. Before and after treatment, symptoms and signs were assessed and first-pass urine was examined for C trachomatis, M genitalium, U urealyticum, and Mycoplasma hominis by polymerase chain reaction-based assays. Results: In 6 of 45 men who had no symptoms and no evidence of inflammation after treatment, nongonococcal urethritis recurred. Of these 6 men, 5 had positive test results for M genitalium before levofloxacin treatment, which remained positive afterward. After the second treatment for recurrent nongonococcal urethritis, one man was still had a positive test result for the mycoplasma and experienced a subsequent recurrence. Conclusions: This study suggests that the persistence of M genitalium in the urethra may be associated with recurrence of nongonococcal urethritis.

  PubMed

• 致死的な重症呼吸器感染症を引き起こすアデノウイルスB7dによる尿道炎症例

  花岡希, 野尻直未, 小長谷昌未, 藤本嗣人, 伊藤晋, 安田満, 安田満, 出口隆

  IASR (Web)   42 ( 4 )  2021

  J-GLOBAL

• 膀胱Nephrogenic adenomaの1例

  大澤 華織, 竹内 慎一, 飯沼 光司, 前川 由佳, 堀江 憲吾, 加藤 卓, 山田 佳輝, 中根 慶太, 水谷 晃輔, 土屋 朋大, 安田 満, 仲野 正博, 酒々井 夏子

  泌尿器科紀要 ( 泌尿器科紀要刊行会 )  64 ( 12 ) 524 - 524  2018.12

• 陰茎癌におけるHPV感染の役割と発癌メカニズムについての検討

  坂本 次郎, 重原 一慶, 中嶋 一史, 川口 昌平, 中嶋 孝夫, 島村 正喜, 安田 満, 小堀 善友, 出口 隆, 溝上 敦

  日本性感染症学会誌 ( (一社)日本性感染症学会 )  29 ( 2 ) 255 - 255  2018.10

• 女子尿道憩室に発生したAdenocarcinomaの1例

  竹内 慎一, 中井 千愛, 高井 学, 亀山 紘司, 山田 佳輝, 中根 慶太, 水谷 晃輔, 土屋 朋大, 安田 満, 横井 繁明, 仲野 正博, 出口 隆, 酒々井 夏子

  泌尿器科紀要 ( 泌尿器科紀要刊行会 )  64 ( 10 ) 421 - 421  2018.10

display all >>

Research Projects 【 display / non-display 】

Research Projects 【 display / non-display 】

• 淋菌薬剤感受性サーベイランスによる薬剤耐性淋菌に対する有効な抗菌化学療法の検討

  基盤研究(C)

  Project Year :

  2022.04

  -

  2025.03

   

  安田 満, 高橋 聡, 佐藤 勇樹

• Drug-resistant Neisseria gonorrhoeae detection by gonococcal antimicrobial susceptibility surveillance and study of drug resistance mechanism and molecular type

  Grant-in-Aid for Scientific Research (C)

  Project Year :

  2018.04

  -

  2021.03

   

  Yasuda Mitsuru

  　View Summary

  From 2018 to 2020, 2,131 strains (608 strains in 2018, 654 strains in 2019, 869 strains in 2020) of Neisseria gonorrhoeae were isolated and preserved from clinical specimens. Of these, drug susceptibility tests were conducted on all strains in 2018 and 2019 and 414 strains in 2020. Almost strains were susceptible to CTRX and SPCM recommended in Japan. 30% were susceptible to CPFX and 90% were susceptible to CFIX. It was considered that these drugs could be used as initial therapeutic agents if they were guaranteed to be susceptible to CPFX and CFIX.

• 淋菌咽頭感染の効果的な治療法の確立

  基盤研究(C)

  Project Year :

  2014.04

  -

  2017.03

   

  安田満

  Authorship： Principal investigator

• 淋菌咽頭感染の効果的な治療法の確立

  基盤研究(C)

  Project Year :

  2014.04

  -

  2017.03

   

  安田満

  Authorship： Principal investigator

• 淋菌咽頭感染の効果的な治療法の確立

  基盤研究(C)

  Project Year :

  2014

  -

  2016

   

  安田 満

  Authorship： Principal investigator

display all >>

Presentations 【 display / non-display 】

Presentations 【 display / non-display 】

• 「Mycoplasma genitaliumと男子非淋菌性尿道炎」

  安田 満

  第53回日本泌尿器科学会中部総会 

  Presentation date： 2003.11

• Epidemiology and Treatumeut for STIs. Neisseria gonorrhoeae intection

  安田 満

  Joint Meeting of International Disease Management Symposium and 3rd Asian UTI/STD Fourm 

  Presentation date： 2005.05

• Multidisciplinary studies on the human diseases caused by mycoplasmas. Mycoplasma genitalium and Ureaplasma urealyticum in urethritis

  安田 満

  oint congress of The 1st Meeting of The Asian Organization for Mycoplasmology and The 31st Meeting of the Japanese Society of Mycoplasmology  (Tokyo) 

  Presentation date： 2004.10

• 「Mycoplasma genitaliumと尿道炎」

  安田 満

  第30回日本マイコプラズマ学会学術集会 

  Presentation date： 2003.10

Social Activities 【 display / non-display 】

Social Activities 【 display / non-display 】

• 非常勤講師

  愛知医科大学  非常勤講師 

  2018.04

  -

  2019.03

• 非常勤講師

  愛知医科大学  非常勤講師  （愛知医科大学） 

  2018.04

  -

  2019.03

  　View Summary

  2