Misc - 大西　浩文

Classification and Regression Treeを使用した高血圧発症予測の検討:端野・壮瞥町研究

三俣兼人, 千葉瑞恵, 古堅真, 古川哲章, 赤坂憲, 大西浩文, 斉藤重幸, 島本和明

日本循環器病予防学会誌   44 ( 2 ) 100  2009年04月

J-GLOBAL

PJ-623 Alterations in Intra-atrial Electromechanical Delay and Left Atrial Function in Healthy Overweight Subjects : A Study of Two-dimensional Speckle Tracking Imaging(PJ105,Echo/Doppler (Others) 2 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Muranaka Atsuko, Yuda Satoshi, Funayama Maki, Yamamoto Hitomi, Kohzu Hidemichi, Doi Takahiro, Kaneko Naofumi, Akasaka Hiroshi, Ohnishi Hirofumi, Shimoshige Shinya, Hashimoto Akiyoshi, Saitoh Shigeyuki, Nakata Tomoaki, Tsuchihashi Kazufumi, Watanabe Naoki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   702 - 702  2009年03月

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唾液中アミラーゼ測定器と身体活動記録機を活用したアジア2カ国(中国,日本)におけるストレスや身体活動と精神的健康度との関連性の研究

大西浩文, 長多好恵, 尚爾華, 尚爾麗, 周勇, 和泉比佐子, 坂内文男, 森満

医科学応用研究財団研究報告   26   66 - 75  2009年02月

J-GLOBAL

高齢者でのアディポネクチン、DHEASと動脈硬化性疾患との関連

磯部 健, 斎藤 重幸, 大西 浩文

研究結果報告書集 ( 三井住友海上福祉財団 )  15   87 - 90  2009年

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地域一般住民において肥満が心形態および心機能に及ぼす影響:正常血圧例と高血圧例での検討-端野・壮瞥町研究-

村中敦子, 湯田聡, 一村真希, 土井崇裕, 山本均美, 神津英至, 赤坂憲, 大西浩文, 下重晋也, 橋本暁佳, 斉藤重幸, 土橋和文, 渡辺直樹, 島本和明

日本心エコー図学会学術集会抄録集   20th  2009年

J-GLOBAL

メタボリックシンドローム、危険因子集積と尿中微量アルブミンとの関連 : 端野・壮瞥町研究

大西 浩文, 斎藤 重幸, 赤坂 憲, 三俣 兼人, 千葉 瑞恵, 古堅 真, 古川 哲章, 森 満, 島本 和明

日本循環器病予防学会誌 = Japanese journal of cardiovascular disease prevention   43 ( 2 ) 132 - 138  2008年10月

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The relationship between hypertension and insulin resistance based on HOMA-R and Matsuda-DeFronzo index: The Tanno and Sobetsu study

M. Furugen, H. Akasaka, S. Saitoh, Y. Miyazaki, H. Ohnishi, K. Shimamoto

JOURNAL OF HYPERTENSION ( LIPPINCOTT WILLIAMS & WILKINS )  26   S122 - S122  2008年06月

研究発表ペーパー・要旨（国際会議）  

学内研究紹介 端野・壮瞥町研究からみた腹部肥満とメタボリックシンドローム

大西 浩文, 斎藤 重幸, 三俣 兼人

札幌医学雑誌 ( 札幌医科大学 )  76 ( 4 ) 23 - 28[含 英語文要旨]  2008年06月

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Impact of both chronic kidney disease and hypertension on cardiovascular events in rural communities in Japan - The Tanno and Sobetsu study

H. Ohnishi, S. Saitoh, H. Akasaka, K. Mitsumata, M. Chiba, M. Furugen, T. Furukawa, M. Mori, K. Shimamoto

JOURNAL OF HYPERTENSION ( LIPPINCOTT WILLIAMS & WILKINS )  26   S116 - S116  2008年06月

研究発表ペーパー・要旨（国際会議）  

地域一般住民高齢者におけるメタボリックシンドローム, インスリン抵抗性と尿中微量アルブミンとの関連 : 端野・壮瞥町研究

田辺谷 徹也, 大西 浩文, 斎藤 重幸, 赤坂 憲, 三俣 兼人, 千葉 瑞恵, 古堅 真, 森 満, 島本 和明

日本老年医学会雑誌 ( 日本老年医学会 )  45 ( 3 ) 302 - 307  2008年05月

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FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Ohnishi Hirofumi, Saitoh Shigeyuki, Akasaka Hiroshi, Mitsumata Kaneto, Chiba Mizue, Furugen Makoto, Furukawa Tetsuaki, Ura Nobuyuki, Mori Mitsuru, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   168 - 168  2008年03月

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地域一般住民高齢者におけるメタボリックシンドローム,インスリン抵抗性と尿中微量アルブミンとの関連‐端野・壮瞥町研究‐

田辺谷徹也, 大西浩文, 大西浩文, 斎藤重幸, 赤坂憲, 三俣兼人, 千葉瑞恵, 古堅真, 森満, 島本和明

日本老年医学会雑誌 ( 日本老年医学会 )  45 ( 3 ) 302 - 307  2008年

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中国・ハルビン市大学生における日常生活活動量とストレス度に関する研究

尚 爾華, 長多 好恵, 大西 浩文

光塩学園女子短期大学紀要 ( 光塩学園女子短期大学 )  ( 10 ) 49 - 53  2008年

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中国・ハルビン市大学生における加速度センサー装置での身体活動量測定と唾液中アミラーゼ活性測定値との関係

尚爾華, 尚爾麗, 周勇, 長多好恵, 大西浩文, 坂内文男, 森満

北海道公衆衛生学雑誌   21 ( 1 ) 66  2007年11月

J-GLOBAL

地域疫学研究からみた生活習慣病,メタボリックシンドローム--端野・壮瞥研究より (特集 40歳からの生活習慣病健診--平成20年の開始に備えて)

斎藤 重幸, 大西 浩文, 赤坂 憲

成人病と生活習慣病 ( 東京医学社 )  37 ( 10 ) 1133 - 1138  2007年10月

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メタボリックシンドロームにおける血清アポ蛋白B48濃度の意義

木下誠, 大西浩文, 斎藤重幸, 島本和明

Ther Res   28 ( 8 ) 1532 - 1536  2007年08月

J-GLOBAL

端野・壮瞥町研究からみた腹部肥満とメタボリックシンドローム

大西 浩文, 斎藤 重幸, 三俣 兼人, 野島 正寛, 園田 智子, 坂内 文男, 森 満, 島本 和明

札幌医学雑誌 = The Sapporo medical journal ( 札幌医科大学 )  76 ( 4 ) 23 - 28  2007年06月

　概要を見る

We have been carrying out a cohort study in two towns in Hokkaido, called "The Tanno and Sobetsu study", for 30 years or more and have reported many data on relationships between various lifestyle-related diseases and occurrence of cardiovascular disease. In this paper, we present data obtained from an epidemiological study on abdominal obesity and metabolic syndrome (MetS) in the Japanese general population. We investigated the prevalence of MetS in the towns of Tanno and Sobetsu. Prevalence of MetS was 26.4% for men and 8.8% for women. These results are supported by the results of a national health and nutrition survey in Japan. Risks of abdominal obesity for occurrence of type 2 diabetes and hypertension (HT) were investigated using our cohort data. The incidences of type 2 diabetes and HT were significantly higher in the abdominal obesity group than in the non-abdominal obesity group. The relative risk of occurrence of type 2 diabetes adjusted for age, sex, SBP, TC and smoking was 2.06 for abdominal obesity, and the relative risk of occurrence of HT adjusted for some confounding factors was 2.33 for abdominal obesity. We investigated the risk of MetS for occurrence of cardiac disease. Cumulative survival rate in individuals with MetS tended to be lower than that in individuals without MetS. Hazards ratio in the individuals with MetS was 1.87 (95% CI: 0.87-4.00, p=0.108). We also investigated the risk of MetS for occurrence of type 2 diabetes. The relative risk of MetS for occurrence of type 2 diabetes was 2.2 after adjustment for age, sex, smoking, total cholesterol and high fasting plasma glucose (fasting plasma glucose ? 110 mg/dl). We investigated the relationship between MetS and health-related quality of life (QOL). The participants were divided into two groups according to age, a non-elderly group (<65 years old) and an elderly group (3 65 years old) and each of these groups was further divided into two groups, a non-MetS group and a MetS group. The percentages of individuals having decreased QOL summary score were compared among these groups. In the non-elderly group, there was no difference between percentages of individuals with decreased QOL summary score in the non-MetS group and MetS group. On the other hand, in the elderly group, the percentage of individuals with decreased QOL summary score was significantly higher in the MetS group than in the non-MetS group. In conclusion, the results presented in this paper suggest that management of abdominal obesity and MetS is important for prevention of CVD events and decrease of health-related QOL.

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Insulin action and secretion, plasma lipids and blood pressure (BP) in Japanese subjects with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT)

Yoshinori Miyazaki, Shigeyuki Saitoh, Hiroshi Akasaka, Hirofumi Ohnishi, Ralph A. Defronzo, Kazuaki Shimamoto

DIABETES ( AMER DIABETES ASSOC )  56   A241 - A241  2007年06月

研究発表ペーパー・要旨（国際会議）  

札幌市における基本健康診査受診と国民健康保険医療費の関連性についての断面研究

森 満, 坂内 文男, 園田 智子, 大西 浩文, 大浦 麻絵, 尚 爾華, 長多 好恵, 朝倉 純代, 和泉 比佐子

札幌医学雑誌 ( 札幌医科大学 )  76 ( 1 ) 13 - 18  2007年06月

　概要を見る

We assessed the relationship between participation in basic health check-ups and the cost of medical expenditure (CME) in the National Health Insurance (NHI) of Sapporo, Japan. The CME in fiscal year 2004, was calculated for each of the 115,966 participants in the basic health check-ups the same year, which as 37.2% of the citizens aged 40 years or over who were covered with the NHI. Moreover, the CME in fiscal year 2004 was also calculated for each of the 28,105 non-participants in the basic health check-ups of the same year who were randomly selected from the residual 62.8% of citizens aged 40 years or over covered with the NHI. Then, through record linkage using identification numbers of the NHI, the CME was calculated according to results of blood chemical tests or other measurements among the participants in the basic health check-up. An analysis of covariance was performed to compare age-adjusted means among the different groups by sex. As a result, the mean CME in the participant group was twice as high as that in the non-participant group. The proportion of experience in attending medical institutions as an outpatient and/or inpatient in the same year was significantly lower in the participant group than that in the non-participant group. The mean CME in ex-smokers was significantly higher than that in non-smokers. The mean CME in lean or obese citizens was significantly higher than that in citizens with normal obesity. Likewise, the mean CMEs in citizens with abnormally high blood sugar as well as abnormally low HDL-cholesterol were significantly higher than those in citizens within normal range of these results. However, a part of the mean CMEs in citizens with either abnormally high blood pressure or abnormally high triglyceride levels were not significantly different with those in citizens within normal range of these results. In conclusion, participation in the health check-up may be associated with low CME through a direct and/or indirect pathway, although it is difficult to infer a causal association with a cross-sectional study.

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PJ-642 A Polymorphism in Promoter Region of CYP4A11 Gene is Associated with a New Onset of Hypertension : the Tanno-Sobetsu Study(Hypertension, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Akasaka Hiroshi, Sugimoto Ken, Katsuya Tomohiro, Saitoh Shigeyuki, Ohnishi Hirofumi, Rakugi Hiromi, Ura Nobuyuki, Ogihara Toshio, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  71   632 - 632  2007年03月

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