Misc - 丹野　雅也

Activation of Sirt1 Suppresses Hypertrophic Response of Cardiomyocytes by Inhibition of H3K9 Acetylation via Proteasome-mediated p300 Degradation.

Atsushi Kuno, Masaya Tanno, Satoko Ishikawa, Yoshiyuki Horio, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  122 ( 21 )  2010年11月

研究発表ペーパー・要旨（国際会議）  

Connexin-43 Contributes to Transmission of MitoK(ATP) Channel-Derived Redox Signal to Akt-GSK-3 beta Pathway in Cardiomyocyte Protection Afforded by G-protein Coupled Receptors

Satoko Ishikawa, Atsushi Kuno, Takayuki Miki, Masaya Tanno, Toshiyuki Yano, Hidemichi Kouzu, Tatsuya Sato, Daisuke Sunaga, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  122 ( 21 )  2010年11月

研究発表ペーパー・要旨（国際会議）  

Ventricular Dysfunction and Blunted Response to Adrenergic Stimulation in Obese Type 2 Diabetes Predispose to Fatal Heart Failure After Infarction: Possible Involvement of MicroRNA-1 Down-Regulation

Akifumi Takada, Takayuki Miki, Masaya Tanno, Hiromu Suzuki, Toshiyuki Yano, Atushi Kuno, Takahito Itoh, Tatsuya Sato, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  122 ( 21 )  2010年11月

研究発表ペーパー・要旨（国際会議）  

Apparently Slight Ventricular Dysfunction Predisposes Obese Type 2 Diabetic Rats to High Mortality After Myocardial Infarction

Hidemichi Kouzu, Akifumi Takada, Takayuki Miki, Masaya Tanno, Toshiyuki Yano, Atsushi Kuno, Takahito Itoh, Tatsuya Satoh, Tetsuji Miura

JOURNAL OF CARDIAC FAILURE ( CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS )  16 ( 9 ) S169 - S169  2010年09月

研究発表ペーパー・要旨（国際会議）  

Activation of SIRT1 modifies histone acetylation/methylation and attenuates cardiomyocyte hypertrophy

Atsushi Kuno, Masaya Tanno, Yoshiyuki Horio

JOURNAL OF PHARMACOLOGICAL SCIENCES ( JAPANESE PHARMACOLOGICAL SOC )  112   200P - 200P  2010年

研究発表ペーパー・要旨（国際会議）  

The SIRT1 Activator Resveratrol Suppresses Cardiomyocyte Hypertrophy by Promoting Histone H3 Lys9 Deacetylation and Tri-methylation

Atsushi Kuno, Masaya Tanno, Toshiyuku Yano, Akifumi Takada, Satoko Ishikawa, Tetsuji Miura, Yoshiyuki Horio, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  120 ( 18 ) S617 - S617  2009年11月

研究発表ペーパー・要旨（国際会議）  

ROS-mediated Dysregulation of Mitochondrial Permeability Transition Pore Underlies Increased Susceptibility of Hypertensive Hypertrophied Hearts to Ischemia/reperfusion Injury

Toshiyuki Yano, Tetsuji Miura, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Takahito Itoh, Akifumi Takada, Tatsuya Satoh, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  120 ( 18 ) S784 - S784  2009年11月

研究発表ペーパー・要旨（国際会議）  

Enhanced ANT-cyclophilin-D interaction underlies reduced anti-infarct tolerance and loss of protective response to erythropoietin in hypertensive hypertrophied hearts

T. Miki, T. Yano, T. Miura, M. Tanno, K. Shimamoto

EUROPEAN HEART JOURNAL ( OXFORD UNIV PRESS )  30   213 - 213  2009年09月

研究発表ペーパー・要旨（国際会議）  

Activation of histone/protein deacetylase SIRT1 by resveratrol induces MnSOD up-regulation via FOXO3a and improves survival of heart failure animals

A. Kuno, M. Tanno, T. Miura, Y. Horio, K. Shimamoto

EUROPEAN HEART JOURNAL ( OXFORD UNIV PRESS )  30   421 - 421  2009年09月

研究発表ペーパー・要旨（国際会議）  

Role of GSK-3beta in negative regulation of mitochondrial permeability transition pore by the mitochondrial KATP channel

T. Miura, Y. Terashima, O. Maas, T. Miki, M. Tanno, S. Ishikawa, K. Shimamoto

EUROPEAN HEART JOURNAL ( OXFORD UNIV PRESS )  30   212 - 213  2009年09月

研究発表ペーパー・要旨（国際会議）  

OE-010 Distinct Roles of PKC ε and p38MAPK in Preconditioning-induced Modulation of Gap Junction Permeability during Ischemia(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Yano Toshiyuki, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Naitoh Kazuyuki, Hotta Hiroyuki, Terashima Yoshiaki, Ito Takahito, Hongo Tamaki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   176 - 176  2009年03月

CiNii

OE-036 Roles of GSK-3 β in Myocardial Protection Afforded by Activation of the Mitochondrial K_<ATP> Channel(OE06,Myocardial Ischemia-reperfusion (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Terashima Yoshiaki, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Yano Toshiyuki, Hotta Hiroyuki, Ishikawa Satoko, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   183 - 183  2009年03月

CiNii

PE-545 Distinct Roles of FOXO Subtypes in SIRT1-mediated Mn-SOD Up-regulation under Oxidative Stress(PE091,Molecular Biology (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)

Kuno Atsushi, Tanno Masaya, Miura Tetsuji, Horio Yoshiyuki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   537 - 537  2009年03月

CiNii

FRS-044 ROS-mediated Enhancement of ANT-cyclophilin-D Interaction Underlies Reduced Anti-infarct Tolerance and Lost Response of Cardiomyocytes to Pro-survival Signaling in Hypertrophied Hearts(FRS9,Novel Mechanisms of Myocardial Ischemia (IHD),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Yano Toshiyuki, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Terashima Yoshiaki, Ito Takahito, Ishikawa Satoko, Takada Akifumi, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   147 - 147  2009年03月

CiNii

DPE-012 Activation of SIRT1, a Histone/Protein Deacetylase, by Resveratrol Up-regulates MnSOD and Suppresses the Progression of Heart Failure(DPE02,Heart Failure, Basic (M),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Tanno Masaya, Kuno Atsushi, Ishikawa Satoko, Miura Tetsuji, Miki Takayuki, Horio Yoshiyuki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   358 - 359  2009年03月

CiNii

OE-008 Homodimeric Erythropoietin (EPO) Receptor Provokes More Potent and Distinct Cytoprotective Signaling Compared with Heterodimeric EPO-common-β Subunit Receptor in the Heart(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Satoh Takahiro, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Yano Toshiyuki, Hotta Hiroyuki, Hongo Tamaki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  73   175 - 176  2009年03月

CiNii

Activation of SIRT1 by resveratrol prevents progression of heart failure and improves the survival in cardiomyopathic hamsters by upregulating MnSOD

Atsushi Kuno, Masaya Tanno, Yoshiyuki Horio

JOURNAL OF PHARMACOLOGICAL SCIENCES ( JAPANESE PHARMACOLOGICAL SOC )  109   112P - 112P  2009年

研究発表ペーパー・要旨（国際会議）  

Rasveratrol, an Activator of Protein Deacetylase SIRT1, Suppresses Oxidative Stress-Induced Call Death by Upregulating MnSOD Expression through Transactivation of FOXO3a

Atsushi Kuno, Masaya Tanno, Tetsuji Miura, Yoshiyuki Horio, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  118 ( 18 ) S391 - S391  2008年10月

研究発表ペーパー・要旨（国際会議）  

Connexin43-dependent And -independent Mechanisms Of Mitochondrial GSK-3 beta Phosphorylation In Protection Of Cardiomyocyte Against Necrosis

Satoko Ishilkawa, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Takahiro Sato, Hiroyuki Hotta, Yoshiaki Terashima, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  118 ( 18 ) S355 - S355  2008年10月

研究発表ペーパー・要旨（国際会議）  

ER Stress Contributes to Dysregulation Of GSK-3 beta-mediated Suppression of Mitochondrial Permeability Transition in Diabetic Hearts

Takayuki Miki, Masaya Tanno, Atsushi Kuno, Toshiyuki Yano, Takahiro Sato, Hiroyuki Hotta, Satoko Ishikawa, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  118 ( 18 ) S290 - S291  2008年10月

研究発表ペーパー・要旨（国際会議）