Misc - 丹野　雅也

Resveratrol activates protein deacetylase SIRT1 and prolongs the survival of heart failure animals by up-regulating MnSOD through transactivation of FOXO3a

Atsushi Kuno, Masaya Tanno, Tetsuji Miura, Yoshiyuki Horio, Kazuaki Shimamoto

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY ( ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD )  45   S19 - S19  2008年10月

研究発表ペーパー・要旨（国際会議）  

DOI

Role of GSK-3 beta modulation in cytoprotective regulation of mitochondrial permeability transition pores by mitochondrial K-ATP channel activation

Yoshiaki Terashima, Tetsuji Miura, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Toshiyuki Yano, Hiroyuki Hotta, Satoko Ishikawa, Kazuaki Shimamoto

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY ( ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD )  45   S22 - S22  2008年10月

研究発表ペーパー・要旨（国際会議）  

DOI

Activation of a Protein Deacetylase, SIRT1, by Resveratrol Suppresses Progression of Heart Failure and Improves Survival by Up-Regulation of Mn-SOD

Masaya Tanno, Atsushi Kuno, Takayuki Miki, Tetsuji Miura, Yoshiyuki Horio, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  118 ( 18 ) S388 - S388  2008年10月

研究発表ペーパー・要旨（国際会議）  

Jak2-mediated cardioprotective signaling is lost in diabetic hearts by up-regulation of calcineurin and enhanced ER stress by the AT1 receptor

Hiroyuki Hotta, Tetsuji Miura, Takayuki Miki, Masaya Tanno, Toshiyuki Yano, Yoshiaki Terashima, Kazuaki Shimamoto

JOURNAL OF CARDIAC FAILURE ( CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS )  14 ( 7 ) S163 - S163  2008年09月

研究発表ペーパー・要旨（国際会議）  

PE-222 Alteration of Akt-GSK-3β Signaling by ER Stress Underlies Failure of Erythropoietin to Protect Diabetic Hearts(Myocardial ischemia/reperfusion, basic/clinical(03)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Miki Takayuki, Miura Tetsuji, Tanno Masaya, Yano Toshiyuki, Satoh Takahiro, Hotta Hiroyuki, Terashima Yoshiaki, Simamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   415 - 416  2008年03月

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PE-333 Resveratrol, An Activator of Longevity Protein SIRT1, Suppresses Progression of Heart Failure Through SIRT1-mediated Cardiomyocyte Protection Against Oxidant Stress(Heart failure, basic(03)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Tanno Masaya, Miura Tetsuji, Miki Takayuki, Yano Toshiyuki, Ohhori Katsuhiko, Horio Yoshiyuki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   443 - 443  2008年03月

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OJ-104 Connexin-43 Contributes to Pro-survival Akt/GSK-3β signaling And Cardimyocyte Protection in a Receptor-specifit Manner(Cell death, apoptosis/necrosis(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Ishikawa Satoko, Miura Tetsuji, Ichikawa Yoshihiko, Tanno Masaya, Ohhori Katsuhiko, Miki Takayuki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   314 - 314  2008年03月

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PJ-005 Impairment of Myocardial Response to Erythropoietin-Induced Protection in Hypertensive Hypertrophied Hearts(Acute myocardial infarction, basic(02)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Yano Toshiyuki, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Satoh Takahiro, Terashima Yoshiaki, Ishikawa Satoko, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   511 - 511  2008年03月

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OE-309 Relationship of the Mitochondrial K_<ATP> Channel and GSK-3β in Enhancement of Myocardial Tolerance against Infarction(Myocardial ischemia/reperfusion, basic/clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Terashima Yoshiaki, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Yano Toshiyuki, Hotta Hiroyuki, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  72   258 - 258  2008年03月

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Resveratrol, an activator of longevity protein SIRT1, suppresses progression of heart failure through SIRT1-mediated cardiomyocyte protection against oxidant stress

Atsushi Kuno, Masaya Tanno, Yoshiyuki Horio

JOURNAL OF PHARMACOLOGICAL SCIENCES ( JAPANESE PHARMACOLOGICAL SOC )  106   213P - 213P  2008年

研究発表ペーパー・要旨（国際会議）  

NAD-dependent histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

Shin Hisahara, Susumu Chiba, Hiroyuki Matsumoto, Masaya Tanno, Shun Shimohama, Makoto Sato, Yoshiyuki Horio

JOURNAL OF PHARMACOLOGICAL SCIENCES ( JAPANESE PHARMACOLOGICAL SOC )  106   114P - 114P  2008年

研究発表ペーパー・要旨（国際会議）  

Suppression of mitochondrial GSK3 beta activity by its Ser9-phosphorylation contributes to cardiomyocyte protection afforded by erythropoietin against oxidative stress-induced apoptosis

Katsuhiko Ohori, Tetsuji Miura, Masaya Tanno, Takayuki Miki, Takahiro Satoh, Yoshiyuki Horio, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  116 ( 16 ) 116 - 116  2007年10月

研究発表ペーパー・要旨（国際会議）  

Ser517-phosphorylation of SIRT1 is required for its PI3K/Akt-mediated nuclear translocation and cardiomyocyte protection against oxidant stress in failing hearts

Masaya Tanno, Tetsup Miura, Takayuki Miki, Toshiyuki Yano, Yoshiyuki Horio, Kazuaki Shimamoto

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  116 ( 16 ) 168 - 168  2007年10月

研究発表ペーパー・要旨（国際会議）  

Modification of Akt/GSK-3 beta signaling and mitochondrial GSK-3 beta by ER stress underlies failure of erythropoietin to protect diabetic hearts

Takayuki Miki, Masaya Tanno, Toshyuki Yano, Takahiro Satoh, Hiroyuki Hotta, Katsuhiko Ohori, Satoko Ishikawa, Tetsuji Miura

CIRCULATION ( LIPPINCOTT WILLIAMS & WILKINS )  116 ( 16 ) 164 - 164  2007年10月

研究発表ペーパー・要旨（国際会議）  

Nuclear translocation of SIRT1 by PI3K/Akt-mediated phosphorylation affords cytoprotection against oxidant stress in post-MI failing hearts

M. Tanno, T. Miura, T. Miki, T. Yano, K. Shimamoto, Y. Horio

EUROPEAN HEART JOURNAL ( OXFORD UNIV PRESS )  28   280 - 280  2007年09月

研究発表ペーパー・要旨（国際会議）  

Reduction of ER stress restored insulin sensitivity and myocardial response to erythropoietin induced-protection in diabetic rats

T. Miki, T. Miura, M. Tanno, T. Yano, K. Naitoh, M. Nishihara, T. Satoh, K. Shimamoto

EUROPEAN HEART JOURNAL ( OXFORD UNIV PRESS )  28   433 - 433  2007年09月

研究発表ペーパー・要旨（国際会議）  

Erythropoietin inhibits cardiomyocyte apoptosis through inactivation of glycogen synthase kinase 3 beta

Katsuhiko Ohori, Tetsuji Miura, Masaya Tanno, Takayuki Miki, Toshiyuki Yano, Yoshiyuki Horio, Kazuaki Shimamoto

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY ( ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD )  42   S82 - S82  2007年06月

研究発表ペーパー・要旨（国際会議）  

DOI

OE-053 Cardioprotective Signaling Provoked by Erythropoietin is Impaired in Diabetic Myocardium(Acute myocardial infarction, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Miki Takayuki, Miura Tetsuji, Tanno Masaya, Yano Toshiyuki, Naitoh Kazuyuki, Nishihara Masahiro, Ohhori Katsuhiko, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  71   164 - 165  2007年03月

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OE-126 Modulation of Mitochondrial Permeability Transition Pore Complex in GSK-3β-mediated Cardiomyocyte Protection(Myocardial ischemia/reperfusion, basic/clinical-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Nishihara Masahiro, Miura Tetsuji, Miki Takayuki, Tanno Masaya, Yano Toshiyuki, Naitoh Kazuyuki, Ohhori Katsuhiko, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  71   183 - 183  2007年03月

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PE-067 Relationships between p38MAPK and PKC in Connexin43-mediated Gap Junction Modulation by Ischemic Preconditioning(Myocardial ischemia/reperfusion, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Naitoh Kazuyuki, Miura Tetsuji, Miki Takayuki, Yano Toshiyuki, Tanno Masaya, Takahashi Akari, Satoh Takahiro, Shimamoto Kazuaki

Circulation journal : official journal of the Japanese Circulation Society ( 社団法人日本循環器学会 )  71   341 - 342  2007年03月

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