論文 - 松浦　基樹

腹腔鏡下子宮筋腫核出術 各施設の工夫 当院における子宮筋腫核出の工夫 内膜に接した変性子宮への対応

玉手 雅人, 長尾 沙智子, 杉尾 明香, 松浦 基樹, 明石 祐史

日本内視鏡外科学会雑誌 ( (一社)日本内視鏡外科学会 )  21 ( 7 ) WS33 - 1  2016年12月

地域母子周産期施設における腹腔鏡手術件数の増加と利点

玉手 雅人, 長尾 沙智子, 杉尾 明香, 松浦 基樹, 明石 祐史

日本内視鏡外科学会雑誌 ( (一社)日本内視鏡外科学会 )  21 ( 7 ) DP78 - 6  2016年12月

腹水セルブロックにおける検討が治療方針決定に有用であった腹膜原発粘液性腺癌の1例

玉手 雅人, 長尾 沙智子, 竹田 倫子, 松浦 基樹, 寺本 瑞絵, 郷久 晴朗, 田中 綾一, 岩崎 雅宏, 齋藤 豪

日本臨床細胞学会雑誌 ( (公社)日本臨床細胞学会 )  55 ( Suppl.2 ) 494 - 494  2016年10月

化学療法による血小板減少に対する加味帰脾湯の効果

山下 芙貴子, 松浦 基樹, 箕輪 智幸, 鈴木 将裕, 田渕 雄大, 高田 さくら, 玉手 雅人, 寺本 瑞絵, 郷久 晴朗, 田中 綾一, 岩崎 雅宏, 齋藤 豪

北海道産科婦人科学会会誌 ( 北海道産科婦人科学会 )  60 ( 1 ) 68 - 68  2016年03月

一期的手術を施行した血管内平滑筋腫の1例

箕輪 智幸, 松浦 基樹, 山下 芙貴子, 鈴木 将裕, 田渕 雄大, 高田 さくら, 玉手 雅人, 寺本 瑞絵, 郷久 晴朗, 田中 綾一, 岩崎 雅宏, 齋藤 豪

北海道産科婦人科学会会誌 ( 北海道産科婦人科学会 )  60 ( 1 ) 62 - 63  2016年03月

術後20年目に局所再発した子宮体癌の1例

鈴木 将裕, 松浦 基樹, 山下 芙貴子, 箕輪 智幸, 田渕 雄大, 高田 さくら, 玉手 雅人, 寺本 瑞絵, 郷久 晴朗, 田中 綾一, 岩崎 雅宏, 齋藤 豪

北海道産科婦人科学会会誌 ( 北海道産科婦人科学会 )  60 ( 1 ) 71 - 71  2016年03月

Intravascular Large B-cell Lymphoma of the Bilateral Ovaries and Uterus in an Asymptomatic Patient with a t(11;22) (q23;q11) Constitutional Translocation

Yasuyuki Shigematsu, Motoki Matsuura, Noriko Nishimura, Naoko Tsuyama, Kengo Takeuchi, Yasuhito Terui, Nobuhiro Takeshima, Kiyohiko Hatake

INTERNAL MEDICINE ( JAPAN SOC INTERNAL MEDICINE )  55 ( 21 ) 3169 - 3174  2016年  [査読有り]

　概要を見る

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of extranodal diffuse large B-cell lymphoma, which is characterized by the intravascular growth of lymphoma cells, aggressive behavior, and an often fatal course. Patients with IVLBCL are usually symptomatic. Although any organ may be involved, localized lesions in the bilateral ovaries and uterus are extremely rare. We experienced a rare case of IVLBCL involving the bilateral ovaries and uterus in an asymptomatic patient with a t(11;22)(q23;q11) constitutional balanced translocation. Its association with the disease remains unknown. Even in asymptomatic situations, IVLBCL is possible, and the uterus and ovaries can be involved.

DOI PubMed

PRIMARY TREATMENT FOR ADVANCED EPITHERIAL OVARIAN CANCER IN A SINGLE INSTITUTION EXPERIENCE

Motoki Matsuura

International Journal of Gynecological Cancer    2016年

Assessment of peritoneal cytology in advanced-stage ovarian cancer patients at interval debulking surgery

Motoki Matsuura

International Journal of Gynecological Cancer    2016年

Preservation of fertility and subsequent childbirth after methotrexate treatment of placenta percreta: a case report

Masato Tamate, Motoki Matsuura, Shutaro Habata, Yushi Akashi, Ryoichi Tanaka, Shinichi Ishioka, Toshiaki Endo, Tsuyoshi Saito

Journal of Medical Case Reports ( BioMed Central Ltd. )  9 ( 1 ) 232  2015年12月  [査読有り]

　概要を見る

Introduction: Placenta percreta is associated with maternal morbidity and mortality. A hysterectomy is often needed to control the bleeding in such cases. However, it has been advocated that placenta percreta be managed conservatively to avoid massive pelvic bleeding and to preserve the patient's fertility. Here, we present a case of placenta percreta diagnosed by magnetic resonance imaging, and treated with systemic administration of methotrexate. Case presentation: A 27-year-old nulliparous Japanese woman at 39 gestational weeks had an uncomplicated vaginal delivery of a 3244-g infant. However, her placenta was not delivered, and we could not remove it manually. Contrast-enhanced magnetic resonance imaging indicated deep myometrial invasion by placental tissue and the whole placenta was strongly enhanced. Seven days post-partum, her serum human chorionic gonadotropin level was 12,656IU/L. Our patient hoped to preserve her uterus for a future pregnancy. She therefore received 13 courses of methotrexate (50mg/week, intravenous injection). Her serum human chorionic gonadotropin level was undetectable 97 days after the first methotrexate injection. At 117 days post-partum, she had a labor-like pain every three minutes and delivered the placenta. Our patient regained normal menses and at follow-up remained in good health. Two years later, she delivered a healthy daughter. Conclusion: We should try to detect placenta percreta in high-risk patients by any means. For low-risk patients, we should give a diagnosis swiftly and control any intrauterine infection and massive bleeding.

DOI PubMed

Secondary debulking surgery for isolated para-aortic nodal recurrence in endometrial cancer requiring partial resection of the inferior vena cava

Kazuyoshi Kato, Motoki Matsuura, Nobuhiro Takeshima

GYNECOLOGIC ONCOLOGY ( ACADEMIC PRESS INC ELSEVIER SCIENCE )  139 ( 3 ) 580 - 581  2015年12月  [査読有り]

　概要を見る

Objective. We report the details of a surgical technique for the cytoreduction of metastatic para-aortic lymph nodes with involvement of the inferior vena cava (IVC) requiring partial resection and repair of the IVC. Methods. A 52-year-old woman presented with endometrial cancer and isolated nodal recurrence involving the IVC. A vascular clamp was applied to the segment of the IVC that the metastatic lymph nodes had involved, and an en bloc resection of the para-aortic lymph nodes with the involved segment of the IVC was performed. Results and conclusion. In this case, a partial resection of the IVC was performed to enable a complete cytoreduction without encroaching on the tumor planes. No intraoperative or postoperative complications, including vascular complications, occurred. This surgical procedure can be adopted for the management of metastatic para-aortic lymph nodes in selected patients. (C) 2015 Elsevier Inc All rights reserved.

DOI PubMed

不妊治療前の治療的腹腔鏡/子宮鏡にて、子宮内膜増殖症を伴う子宮ポリープ状異型腺筋腫(APAM)と診断した1例

玉手 雅人, 明石 祐史, 長尾 沙智子, 西澤 庸子, 杉尾 明香, 松浦 基樹, 齋藤 豪

日本内視鏡外科学会雑誌 ( (一社)日本内視鏡外科学会 )  20 ( 7 ) OS217 - 6  2015年12月

Palonosetron in combination with 1-day versus 3-day dexamethasone for prevention of nausea and vomiting following paclitaxel and carboplatin in patients with gynecologic cancers: A randomized, multicenter, phase-II trial

Motoki Matsuura, Seiro Satohisa, Mizue Teramoto, Ryoichi Tanaka, Masahiro Iwasaki, Akira Nishikawa, Masahiro Mizunuma, Satoshi Tanaka, Osamu Hayakawa, Tsuyoshi Saito

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH ( WILEY-BLACKWELL )  41 ( 10 ) 1607 - 1613  2015年10月  [査読有り]

　概要を見る

AimChemotherapy-induced nausea and vomiting (CINV) can affect a patient's quality of life, leading to poor compliance with further treatments. Previous studies have provided minimal data about carboplatin-based regimens. Female sex is a known risk factor for CINV. The purpose of this study was to evaluate palonosetron plus single-dose dexamethasone (DEX) for preventing CINV caused by carboplatin plus paclitaxel combination therapy (TC regimen) in patients with gynecologic cancers. Material and MethodsPatients were recruited for this phase-II, multicenter, randomized trial from 12 hospitals in Hokkaido, Japan. Eligible patients were women with uterine cervical, endometrial or ovarian cancer scheduled to receive conventional TC regimen or dose-dense TC regimen; 116 patients were randomly assigned to receive palonosetron in combination with 1-day DEX or 3-day DEX. ResultsDuring the overall period, complete response (CR) was observed in 67.9% (95% confidence interval, 53.7-80.1) of patients in the 3-day DEX arm, and 60.7% (95% confidence interval, 46.8-73.5) of patients in the 1-day DEX arm; CR was significantly lower in the 1-day DEX arm if motion sickness was already present (P=0.0370). In the severe hyperemesis gravidarum cohort, CR in the 1-day DEX arm tended to be lower than in the 3-day DEX arm. ConclusionCombination therapy of palonosetron and 1-day DEX was effective for subjects undergoing a TC regimen for gynecologic cancers. However, the possibility of reduced efficacy of 1-day only DEX therapy in women undergoing a TC regimen could not be refuted and requires further investigation.

DOI PubMed

腹腔鏡および子宮鏡にて子宮内膜増殖症を伴う子宮ポリープ状異型腺筋腫と診断した1例

玉手 雅人, 寺本 瑞絵, 竹田 倫子, 松浦 基樹, 郷久 晴朗, 田中 綾一, 岩崎 雅宏, 齋藤 豪

日本臨床細胞学会雑誌 ( (公社)日本臨床細胞学会 )  54 ( Suppl.2 ) 561 - 561  2015年10月

[One-stage resection of intravenous leiomyomatosis extending into the right atrium].

Yanagiya A, Yamada O, Nanbu T, Hamada H, Takada J, Matsuura M, Tabuchi Y

Kyobu geka. The Japanese journal of thoracic surgery ( 南江堂 )  68 ( 3 ) 188 - 191  2015年03月  [査読有り]

PubMed CiNii

Rap1GAPの発現と子宮体部類内膜腺癌の分化度(Expression of Rap1GAP and differentiation of endometrioid adenocarcinoma in endometrial cancer)

玉手 雅人, 田中 綾一, 幅田 周太朗, 杉尾 明香, 松浦 基樹, 郷久 晴朗, 岩崎 雅宏, 齋藤 豪

日本癌学会総会記事 ( (一社)日本癌学会 )  73回   P - 2080  2014年09月

Prediction of the therapeutic effect of dienogest in ovarian endometrial cysts using the apparent diffusion coefficient

Motoki Matsuura, Masato Tamate, Yuta Tabuchi, Sakura Takada, Ryoichi Tanaka, Masahiro Iwasaki, Tsuyoshi Saito

GYNECOLOGICAL ENDOCRINOLOGY ( INFORMA HEALTHCARE )  30 ( 8 ) 597 - 599  2014年08月  [査読有り]

　概要を見る

The purpose of this study was to investigate whether apparent diffusion coefficient (ADC) mean values can be used for predicting the treatment response in ovarian endometrial cyst patients with dienogest (DNG) administration. Eighteen patients received DNG (2 mg/day, orally) for 60 days, among whom 26 ovarian endometrial cysts were retrospectively identified. Mean ADC values of individual ovarian endometrial cysts were obtained by ADC maps inside the tumor. There was a significant correlation between ADC values and reduction ratio. When calculating the mean ADC values for three groups; more than 50%, 50-25% and less than 25%, ADC values significantly increased with increasing reduction ratio; 2.05 x 10(-3) mm(2)/s, 1.28 x 10(-3) mm(2)/s and 0.94 x 10(-3) mm(2)/s, respectively (p = 0.0180). Multiple regression analysis by reduction ratio (%), ADC mean values (x 10(-3) mm(2)/s), tumor longest diameter (cm) and CA125 (Wml) revealed that tumor reduction ratio by DNG administration could be predicted by the following equation; R=19.3 + 24.0x - 0.4y + 0.1z (R: Reduction ratio, x: ADC mean, y: Longest diameter, z: CA125). In conclusion, the ADC mean value is useful for the prediction of the treatment response in ovarian endometrial cyst patients with DNG administration.

DOI PubMed

Low-dose SN-38 with paclitaxel induces lethality in human uterine cervical adenocarcinoma cells by increasing caspase activity

Mizue Teramoto, Takahiro Suzuki, Seiro Satohisa, Yushi Akashi, Motoki Matsuura, Miwa Suzuki, Ryoichi Tanaka, Tsuyoshi Saito

MEDICAL MOLECULAR MORPHOLOGY ( SPRINGER JAPAN KK )  47 ( 1 ) 31 - 37  2014年03月  [査読有り]

　概要を見る

Combination of anticancer drugs may provide a rational molecular basis for novel chemotherapeutic strategies. Paclitaxel and SN-38 (an active metabolite of CPT-11) are effective for many kinds of cancer. Therefore, we investigated the possibility that combination of these drugs could be effective against cervical adenocarcinoma cells. In this study, we examined cell growth inhibition after 96 h using the MTT assay and examined the release of fragmented DNA into the cytoplasm during apoptotic cell death by PI staining. Single and combined use of paclitaxel and SN-38 produced significant cytolethality against the cervical adenocarcinoma cell line CAC-1. Addition of a low concentration of SN-38 reduced the IC50 value of paclitaxel compared to that without SN-38, although the low concentration of paclitaxel did not enhance the cytotoxicity of SN-38. FACS scan analysis suggested that these drugs induced apoptosis and cell cycle arrest, and that caspase-3 and -7 were activated in the process. MTT assay and the IC50 demonstrated that paclitaxel had strong cytotoxicity against CAC-1 as well as other cancer cells. In this study, though only a single cell line was used for the experiment and the data are limited, our results suggest that paclitaxel together with low-dose CPT-11 is a promising basis for a new combination cancer chemotherapy.

DOI PubMed

手術手技を定型化することによる手術成績の変化に関する検討

田渕 雄大, 松浦 基樹, 玉手 雅人, 明石 祐史

日本内視鏡外科学会雑誌 ( (一社)日本内視鏡外科学会 )  18 ( 7 ) 633 - 633  2013年11月

腹腔鏡下子宮筋腫核出術における術前GnRHagonistの有用性と筋腫縮小率の予測

玉手 雅人, 田渕 雄大, 足立 英文, 杉尾 明香, 松浦 基樹, 森下 美幸, 明石 祐史

日本内視鏡外科学会雑誌 ( (一社)日本内視鏡外科学会 )  18 ( 7 ) 634 - 634  2013年11月